SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nsj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 5nsj PRE-GLYCOPROTEIN
POLYPROTEIN GP
COMPLEX
(Whitewater
Arroyo
mammarenavirus) 		5 / 12 ALA A 173
LEU A 140
LEU A 106
PHE A 147
MET A 144
 None
 0.89A 1dtlA-5nsjA:
undetectable		 1dtlA-5nsjA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 5nsj PRE-GLYCOPROTEIN
POLYPROTEIN GP
COMPLEX
(Whitewater
Arroyo
mammarenavirus) 		5 / 12 MET A 190
THR A 178
ILE A 177
VAL A 186
LEU A 210
 None
 1.36A 1wsvA-5nsjA:
undetectable		 1wsvA-5nsjA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 5nsj PRE-GLYCOPROTEIN
POLYPROTEIN GP
COMPLEX
(Whitewater
Arroyo
mammarenavirus) 		5 / 12 MET A 190
THR A 178
ILE A 177
VAL A 186
LEU A 210
 None
 1.34A 1wsvB-5nsjA:
undetectable		 1wsvB-5nsjA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5nsj PRE-GLYCOPROTEIN
POLYPROTEIN GP
COMPLEX
(Whitewater
Arroyo
mammarenavirus) 		5 / 12 LEU A 151
PHE A 157
ILE A 127
PRO A 200
VAL A 209
 None
 1.34A 3w1wB-5nsjA:
undetectable		 3w1wB-5nsjA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5nsj PRE-GLYCOPROTEIN
POLYPROTEIN GP
COMPLEX
(Whitewater
Arroyo
mammarenavirus) 		4 / 7 ILE A 162
GLN A 160
PRO A 159
ILE A 177
 None
 1.08A 4w5oA-5nsjA:
undetectable		 4w5oA-5nsjA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5nsj PRE-GLYCOPROTEIN
POLYPROTEIN GP
COMPLEX
(Whitewater
Arroyo
mammarenavirus) 		4 / 7 ILE A 162
GLN A 160
PRO A 159
ILE A 177
 None
 1.07A 4z4gA-5nsjA:
undetectable		 4z4gA-5nsjA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5nsj PRE-GLYCOPROTEIN
POLYPROTEIN GP
COMPLEX
(Whitewater
Arroyo
mammarenavirus) 		4 / 9 ILE A 177
ILE A 211
ILE A 104
LEU A  94
 None
 0.82A 5vkqB-5nsjA:
undetectable
5vkqC-5nsjA:
undetectable		 5vkqB-5nsjA:
6.87
5vkqC-5nsjA:
6.87