SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nt7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_C_CCSC47_0 (GLUTATHIONE S-TRANSFERASE)	5nt7	ATP-DEPENDENT RNA HELICASE VASA, ISOFORM A (Drosophila melanogaster)	4 / 6	THR B 615 LEU B 609 GLY B 613 LYS B 466	None	1.16A	1gtiC-5nt7B: undetectable	1gtiC-5nt7B: 20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QA0_A_SHHA404_2 (HISTONE DEACETYLASE 8)	5nt7	ATP-DEPENDENT RNA HELICASE VASA, ISOFORM A (Drosophila melanogaster)	3 / 3	PRO B 567 MET B 566 TYR B 573	None	0.89A	4qa0B-5nt7B: 3.9	4qa0B-5nt7B: 19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QA0_B_SHHB404_1 (HISTONE DEACETYLASE 8)	5nt7	ATP-DEPENDENT RNA HELICASE VASA, ISOFORM A (Drosophila melanogaster)	3 / 3	PRO B 567 MET B 566 TYR B 573	None	0.87A	4qa0A-5nt7B: 4.2	4qa0A-5nt7B: 19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QA2_A_SHHA404_2 (HISTONE DEACETYLASE 8)	5nt7	ATP-DEPENDENT RNA HELICASE VASA, ISOFORM A (Drosophila melanogaster)	3 / 3	PRO B 567 MET B 566 TYR B 573	None	1.04A	4qa2B-5nt7B: 4.2	4qa2B-5nt7B: 19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FDY_U_DB8U302_1 (-)	5nt7	ATP-DEPENDENT RNA HELICASE VASA, ISOFORM A (Drosophila melanogaster)	5 / 9	VAL B 496 PHE B 508 SER B 507 LEU B 509 ILE B 544	None	0.92A	6fdyU-5nt7B: undetectable	6fdyU-5nt7B: 20.64

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GTI_C_CCSC47_0","GLUTATHIONE S-TRANSFERASE","5nt7","ATP-DEPENDENT RNA HELICASE VASA, ISOFORM A","Drosophila melanogaster",4,"THR B 615;LEU B 609;GLY B 613;LYS B 466","None","1.16A","1gtiC-5nt7B:undetectable","1gtiC-5nt7B:20.64"],["4QA0_A_SHHA404_2","HISTONE DEACETYLASE 8;HISTONE DEACETYLASE 8","5nt7","ATP-DEPENDENT RNA HELICASE VASA, ISOFORM A","Drosophila melanogaster",3,"PRO B 567;MET B 566;TYR B 573","None","0.89A","4qa0B-5nt7B:3.9","4qa0B-5nt7B:19.10"],["4QA0_B_SHHB404_1","HISTONE DEACETYLASE 8;HISTONE DEACETYLASE 8","5nt7","ATP-DEPENDENT RNA HELICASE VASA, ISOFORM A","Drosophila melanogaster",3,"PRO B 567;MET B 566;TYR B 573","None","0.87A","4qa0A-5nt7B:4.2","4qa0A-5nt7B:19.10"],["4QA2_A_SHHA404_2","HISTONE DEACETYLASE 8;HISTONE DEACETYLASE 8","5nt7","ATP-DEPENDENT RNA HELICASE VASA, ISOFORM A","Drosophila melanogaster",3,"PRO B 567;MET B 566;TYR B 573","None","1.04A","4qa2B-5nt7B:4.2","4qa2B-5nt7B:19.10"],["6FDY_U_DB8U302_1","-","5nt7","ATP-DEPENDENT RNA HELICASE VASA, ISOFORM A","Drosophila melanogaster",5,"VAL B 496;PHE B 508;SER B 507;LEU B 509;ILE B 544","None","0.92A","6fdyU-5nt7B:undetectable","6fdyU-5nt7B:20.64"]]