SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nuq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 5nuq PROBABLE
PHOSPHOLIPID-BINDING
LIPOPROTEIN MLAA
(Serratia
marcescens) 		5 / 11 ASN G 210
ASP G 144
GLY G 118
PHE G 117
TYR G 128
 None
 1.35A 1ju6A-5nuqG:
undetectable		 1ju6A-5nuqG:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 5nuq PROBABLE
PHOSPHOLIPID-BINDING
LIPOPROTEIN MLAA
(Serratia
marcescens) 		5 / 10 ASN G 210
ASP G 144
GLY G 118
PHE G 117
TYR G 128
 None
 1.35A 1ju6C-5nuqG:
undetectable		 1ju6C-5nuqG:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JUJ_A_LYAA315_1
(THYMIDYLATE SYNTHASE)		 5nuq PROBABLE
PHOSPHOLIPID-BINDING
LIPOPROTEIN MLAA
(Serratia
marcescens) 		5 / 10 ASN G 210
ASP G 144
GLY G 118
PHE G 117
TYR G 128
 None
 1.29A 1jujA-5nuqG:
undetectable		 1jujA-5nuqG:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JUJ_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 5nuq PROBABLE
PHOSPHOLIPID-BINDING
LIPOPROTEIN MLAA
(Serratia
marcescens) 		5 / 10 ASN G 210
ASP G 144
GLY G 118
PHE G 117
TYR G 128
 None
 1.29A 1jujB-5nuqG:
undetectable		 1jujB-5nuqG:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JUJ_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 5nuq PROBABLE
PHOSPHOLIPID-BINDING
LIPOPROTEIN MLAA
(Serratia
marcescens) 		5 / 10 ASN G 210
ASP G 144
GLY G 118
PHE G 117
TYR G 128
 None
 1.29A 1jujC-5nuqG:
undetectable		 1jujC-5nuqG:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JUJ_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 5nuq PROBABLE
PHOSPHOLIPID-BINDING
LIPOPROTEIN MLAA
(Serratia
marcescens) 		5 / 10 ASN G 210
ASP G 144
GLY G 118
PHE G 117
TYR G 128
 None
 1.29A 1jujD-5nuqG:
undetectable		 1jujD-5nuqG:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 5nuq PROBABLE
PHOSPHOLIPID-BINDING
LIPOPROTEIN MLAA
(Serratia
marcescens) 		3 / 3 GLU G 145
HIS G 205
THR G 141
 None
 0.88A 3hkuA-5nuqG:
undetectable		 3hkuA-5nuqG:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 5nuq PROBABLE
PHOSPHOLIPID-BINDING
LIPOPROTEIN MLAA
(Serratia
marcescens) 		4 / 6 SER G 139
TYR G 131
ASP G 192
THR G  22
 None
 1.11A 3q70A-5nuqG:
undetectable		 3q70A-5nuqG:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 5nuq PROBABLE
PHOSPHOLIPID-BINDING
LIPOPROTEIN MLAA
(Serratia
marcescens) 		3 / 3 ASN G  90
ALA G 102
ARG G  86
 None
 0.81A 3tj7C-5nuqG:
undetectable
3tj7D-5nuqG:
undetectable		 3tj7C-5nuqG:
20.16
3tj7D-5nuqG:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5nuq PROBABLE
PHOSPHOLIPID-BINDING
LIPOPROTEIN MLAA
(Serratia
marcescens) 		4 / 6 GLY G 146
GLU G 145
ASP G 151
ASP G 144
 None
 0.92A 4uckB-5nuqG:
undetectable		 4uckB-5nuqG:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)		 5nuq PROBABLE
PHOSPHOLIPID-BINDING
LIPOPROTEIN MLAA
(Serratia
marcescens) 		5 / 12 ASN G 210
ASP G 144
GLY G 118
PHE G 117
TYR G 128
 None
 1.26A 6r2eA-5nuqG:
undetectable		 6r2eA-5nuqG:
20.26