SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nuv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 8 GLY A 426
HIS A 407
ALA A 448
THR A 445
 None
 0.88A 1gtfN-5nuvA:
undetectable
1gtfO-5nuvA:
undetectable		 1gtfN-5nuvA:
12.58
1gtfO-5nuvA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		3 / 3 ASP A 454
LEU A 496
LEU A 494
 None
 0.75A 1ikeA-5nuvA:
undetectable		 1ikeA-5nuvA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		5 / 12 HIS A 576
VAL A 328
PHE A 330
VAL A 351
LEU A 603
 None
 1.13A 1oq5A-5nuvA:
undetectable		 1oq5A-5nuvA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ECP_B_ACRB992_1
(MALTODEXTRIN
PHOSPHORYLASE)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		5 / 10 ASN A 386
ASP A 454
ARG A 539
HIS A 407
ALA A 384
 None
 1.45A 2ecpB-5nuvA:
undetectable		 2ecpB-5nuvA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		5 / 12 PHE A 374
SER A 586
LEU A 603
VAL A 593
CYH A 356
 None
 1.14A 3u9fB-5nuvA:
undetectable
3u9fC-5nuvA:
undetectable		 3u9fB-5nuvA:
19.68
3u9fC-5nuvA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		5 / 12 SER A 331
PHE A 374
SER A 586
LEU A 603
VAL A 593
 None
 1.43A 3u9fB-5nuvA:
undetectable
3u9fC-5nuvA:
undetectable		 3u9fB-5nuvA:
19.68
3u9fC-5nuvA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		5 / 12 SER A 331
SER A 586
LEU A 603
PHE A 318
VAL A 593
 None
 1.36A 3u9fB-5nuvA:
undetectable
3u9fC-5nuvA:
undetectable		 3u9fB-5nuvA:
19.68
3u9fC-5nuvA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		5 / 10 SER A 331
SER A 586
LEU A 603
PHE A 318
VAL A 593
 None
 1.38A 3u9fE-5nuvA:
undetectable		 3u9fE-5nuvA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		5 / 12 SER A 331
SER A 586
LEU A 603
PHE A 318
VAL A 593
 None
 1.29A 3u9fH-5nuvA:
undetectable
3u9fI-5nuvA:
undetectable		 3u9fH-5nuvA:
19.68
3u9fI-5nuvA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		5 / 12 SER A 331
SER A 586
LEU A 603
PHE A 318
VAL A 593
 None
 1.41A 3u9fJ-5nuvA:
undetectable
3u9fK-5nuvA:
undetectable		 3u9fJ-5nuvA:
19.68
3u9fK-5nuvA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		5 / 10 SER A 331
SER A 586
LEU A 603
PHE A 318
VAL A 593
 None
 1.42A 3u9fK-5nuvA:
undetectable		 3u9fK-5nuvA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 5 LYS A 359
LEU A 348
GLU A 350
LEU A 336
 None
 1.27A 4k4yA-5nuvA:
undetectable		 4k4yA-5nuvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 4 LYS A 359
LEU A 348
GLU A 350
LEU A 336
 None
 1.27A 4k4yE-5nuvA:
undetectable		 4k4yE-5nuvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 5 LYS A 359
LEU A 348
GLU A 350
LEU A 336
 None
 1.29A 4k4yI-5nuvA:
undetectable		 4k4yI-5nuvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 8 TRP A 435
SER A 390
HIS A 407
ILE A 455
 None
 1.11A 4ms4A-5nuvA:
undetectable		 4ms4A-5nuvA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		5 / 12 SER A 579
THR A 339
ALA A 327
ALA A 582
ASN A 326
 None
 1.49A 4u15A-5nuvA:
undetectable		 4u15A-5nuvA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 8 GLY A 426
HIS A 407
ALA A 448
THR A 445
 None
 0.87A 5eevL-5nuvA:
undetectable
5eevV-5nuvA:
undetectable		 5eevL-5nuvA:
12.58
5eevV-5nuvA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 8 GLY A 426
HIS A 407
ALA A 448
THR A 445
 None
 0.87A 5eewL-5nuvA:
undetectable
5eewV-5nuvA:
undetectable		 5eewL-5nuvA:
12.58
5eewV-5nuvA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 8 GLY A 426
HIS A 407
ALA A 448
THR A 445
 None
 0.87A 5eezL-5nuvA:
undetectable
5eezV-5nuvA:
undetectable		 5eezL-5nuvA:
12.58
5eezV-5nuvA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 8 GLY A 426
HIS A 407
ALA A 448
THR A 445
 None
 0.87A 5ef1L-5nuvA:
undetectable
5ef1V-5nuvA:
undetectable		 5ef1L-5nuvA:
12.58
5ef1V-5nuvA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 8 GLY A 426
HIS A 407
ALA A 448
THR A 445
 None
 0.87A 5ef2L-5nuvA:
undetectable
5ef2V-5nuvA:
undetectable		 5ef2L-5nuvA:
12.58
5ef2V-5nuvA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 8 GLY A 426
HIS A 407
ALA A 448
THR A 445
 None
 0.87A 5ef3L-5nuvA:
undetectable
5ef3V-5nuvA:
undetectable		 5ef3L-5nuvA:
12.58
5ef3V-5nuvA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 7 ALA A 601
VAL A 593
TRP A 604
PRO A 311
 None
 0.94A 6cduA-5nuvA:
undetectable
6cduE-5nuvA:
undetectable		 6cduA-5nuvA:
21.15
6cduE-5nuvA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 6 VAL A 593
TRP A 604
PRO A 311
ALA A 601
 None
 0.93A 6cduB-5nuvA:
undetectable
6cduC-5nuvA:
undetectable		 6cduB-5nuvA:
21.15
6cduC-5nuvA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5nuv AUTOPHAGY-RELATED
PROTEIN 16-1
(Homo
sapiens) 		4 / 7 VAL A 593
TRP A 604
PRO A 311
ALA A 601
 None
 0.96A 6cduH-5nuvA:
undetectable
6cduI-5nuvA:
undetectable		 6cduH-5nuvA:
21.15
6cduI-5nuvA:
21.15