SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nv3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  71
TRP A  72
 None
 0.71A 1av2A-5nv3A:
undetectable
1av2B-5nv3A:
undetectable		 1av2A-5nv3A:
3.90
1av2B-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.79A 1av2C-5nv3A:
undetectable
1av2D-5nv3A:
undetectable		 1av2C-5nv3A:
3.90
1av2D-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 TRP A  72
ALA A  16
VAL A  71
 None
 0.61A 1bdwA-5nv3A:
undetectable
1bdwB-5nv3A:
undetectable		 1bdwA-5nv3A:
3.90
1bdwB-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 6 PHE A 312
ILE A 310
LYS A 317
ALA A 316
 None
 1.17A 1hk2A-5nv3A:
undetectable		 1hk2A-5nv3A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 8 MET A 388
LEU A 199
GLY A 405
TRP A 463
 None
None
CAP  A1001 (-3.7A)
None
 1.01A 1hrkA-5nv3A:
undetectable		 1hrkA-5nv3A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 8 MET A 388
LEU A 199
GLY A 405
TRP A 463
 None
None
CAP  A1001 (-3.7A)
None
 1.01A 1hrkB-5nv3A:
undetectable		 1hrkB-5nv3A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		5 / 11 GLU A 193
ILE A 414
GLY A 417
THR A 407
GLY A 198
 None
 1.28A 1i7qA-5nv3A:
undetectable		 1i7qA-5nv3A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_C_BEZC1502_0
(ANTHRANILATE
SYNTHASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		5 / 10 GLU A 193
ILE A 414
GLY A 417
THR A 407
GLY A 198
 None
 1.24A 1i7qC-5nv3A:
undetectable		 1i7qC-5nv3A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.90A 1jnoA-5nv3A:
undetectable		 1jnoA-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.90A 1jnoB-5nv3A:
undetectable		 1jnoB-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.91A 1jo3A-5nv3A:
undetectable		 1jo3A-5nv3A:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.91A 1jo3B-5nv3A:
undetectable		 1jo3B-5nv3A:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.93A 1jo4A-5nv3A:
undetectable		 1jo4A-5nv3A:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.93A 1jo4B-5nv3A:
undetectable		 1jo4B-5nv3A:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.90A 1magA-5nv3A:
undetectable		 1magA-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.90A 1magB-5nv3A:
undetectable		 1magB-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.90A 1ng8A-5nv3A:
undetectable		 1ng8A-5nv3A:
5.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.90A 1ng8B-5nv3A:
undetectable		 1ng8B-5nv3A:
5.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.86A 1nrmA-5nv3A:
undetectable		 1nrmA-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.86A 1nrmB-5nv3A:
undetectable		 1nrmB-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.93A 1nruA-5nv3A:
undetectable		 1nruA-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.93A 1nruB-5nv3A:
undetectable		 1nruB-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		5 / 12 VAL A 314
ILE A 123
PHE A 127
ILE A 122
ARG A 136
 None
 1.01A 1qhsA-5nv3A:
undetectable		 1qhsA-5nv3A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  71
TRP A  72
 None
 0.72A 1w5uA-5nv3A:
undetectable
1w5uB-5nv3A:
undetectable		 1w5uA-5nv3A:
3.90
1w5uB-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.83A 1w5uC-5nv3A:
undetectable
1w5uD-5nv3A:
undetectable		 1w5uC-5nv3A:
3.90
1w5uD-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 TRP A  68
ALA A  16
VAL A  18
 None
 0.72A 2izqA-5nv3A:
undetectable
2izqB-5nv3A:
undetectable		 2izqA-5nv3A:
3.90
2izqB-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 TRP A  72
ALA A  16
VAL A  71
 None
 0.64A 2izqC-5nv3A:
undetectable
2izqD-5nv3A:
undetectable		 2izqC-5nv3A:
3.90
2izqD-5nv3A:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 5 PRO A  91
PRO A  96
GLY A  97
TYR A  99
 None
 1.08A 2jkjD-5nv3A:
undetectable		 2jkjD-5nv3A:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 5 PRO A  91
PRO A  96
GLY A  97
TYR A  99
 None
 1.08A 2jkjF-5nv3A:
undetectable		 2jkjF-5nv3A:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 1
(Rhodobacter
sphaeroides) 		4 / 6 PRO I 107
HIS I  42
ASP A 165
TYR I  79
 None
 1.12A 2lh8A-5nv3I:
undetectable		 2lh8A-5nv3I:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 1
(Rhodobacter
sphaeroides) 		4 / 5 LEU A 425
ALA A 427
LEU A 430
MET I  96
 None
 1.26A 2oaxA-5nv3A:
undetectable		 2oaxA-5nv3A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		5 / 12 HIS A 293
ILE A 383
LEU A 401
GLY A 173
ALA A 379
 KCX  A 203 ( 4.8A)
None
None
None
None
 0.99A 2oc8A-5nv3A:
undetectable		 2oc8A-5nv3A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 1
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		3 / 3 LEU I  11
PRO I  12
ARG A 436
 None
 0.42A 2qd5A-5nv3I:
undetectable		 2qd5A-5nv3I:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 6 GLN A 415
ALA A 226
ALA A 230
THR A 234
 None
 1.06A 2xfhA-5nv3A:
undetectable		 2xfhA-5nv3A:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 1
(Rhodobacter
sphaeroides) 		4 / 5 LEU I  35
GLY I  52
GLU I  49
CYH I  71
 None
 0.90A 3aiaA-5nv3I:
undetectable
3aiaB-5nv3I:
undetectable		 3aiaA-5nv3I:
22.33
3aiaB-5nv3I:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 MET A 252
VAL A 267
GLU A 257
 None
 0.91A 3c6gA-5nv3A:
undetectable		 3c6gA-5nv3A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 CYH A 350
PRO A 353
ASP A 398
 None
 0.97A 3hlwB-5nv3A:
undetectable		 3hlwB-5nv3A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 ALA A  16
VAL A  18
TRP A  68
 None
 0.73A 3l8lA-5nv3A:
undetectable
3l8lB-5nv3A:
undetectable		 3l8lA-5nv3A:
3.90
3l8lB-5nv3A:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		3 / 3 TRP A  72
ALA A  16
VAL A  71
 None
 0.65A 3l8lC-5nv3A:
undetectable
3l8lD-5nv3A:
undetectable		 3l8lC-5nv3A:
3.90
3l8lD-5nv3A:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		5 / 12 THR A  65
PHE A  42
ILE A 310
ILE A 115
ALA A 116
 None
 1.20A 3nxuB-5nv3A:
undetectable		 3nxuB-5nv3A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 4 GLY A 382
GLY A 334
THR A 331
LEU A 391
 CAP  A1001 (-3.8A)
None
None
None
 0.81A 3si7C-5nv3A:
undetectable
3si7D-5nv3A:
undetectable		 3si7C-5nv3A:
19.36
3si7D-5nv3A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		5 / 9 ARG A 163
VAL A 375
ILE A 281
PRO A 154
THR A 155
 None
 1.07A 3spkA-5nv3A:
undetectable		 3spkA-5nv3A:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 8 GLY A 168
GLY A 198
ASN A 421
MET A 388
 None
 1.00A 3v3nC-5nv3A:
undetectable		 3v3nC-5nv3A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 1
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		4 / 7 GLU A 434
TYR I  25
ARG A 432
GLY A 168
 None
 1.02A 4fgzA-5nv3A:
undetectable		 4fgzA-5nv3A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		5 / 12 TYR A 150
ALA A 116
TYR A 275
ILE A 315
GLY A 323
 None
 1.43A 4iilA-5nv3A:
3.1		 4iilA-5nv3A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		6 / 12 PHE A 201
GLY A 239
VAL A 265
ILE A 266
LEU A 171
ILE A 157
 None
 1.44A 4pd4C-5nv3A:
undetectable		 4pd4C-5nv3A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		5 / 12 PHE A 312
ILE A 123
LEU A 271
LEU A 319
TYR A 275
 None
 0.96A 4xumA-5nv3A:
undetectable		 4xumA-5nv3A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		5 / 12 GLU A 206
ILE A 115
GLY A 323
LEU A 327
MET A 294
 MG  A1002 ( 3.0A)
None
None
None
None
 1.36A 5esgA-5nv3A:
undetectable		 5esgA-5nv3A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		5 / 12 ILE A 115
TYR A 275
GLY A 323
LEU A 327
HIS A 328
 None
None
None
None
CAP  A1001 (-4.0A)
 1.39A 5esgA-5nv3A:
undetectable		 5esgA-5nv3A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 5 GLY A 247
THR A 248
GLY A 309
LEU A 271
 None
 0.76A 5jlcA-5nv3A:
undetectable		 5jlcA-5nv3A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		5 / 12 ILE A 115
TYR A 275
GLY A 323
LEU A 327
HIS A 328
 None
None
None
None
CAP  A1001 (-4.0A)
 1.41A 5v5zA-5nv3A:
undetectable		 5v5zA-5nv3A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 6 PHE A 220
ARG A 219
ILE A 244
ASP A 204
 None
None
None
KCX  A 203 ( 4.4A)
 1.47A 6dhbA-5nv3A:
undetectable		 6dhbA-5nv3A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA807_0
(GEPHYRIN)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 4 PRO A 377
LEU A 327
VAL A 349
ARG A 351
 None
 1.48A 6fgdA-5nv3A:
1.7		 6fgdA-5nv3A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
RIBULOSE
BISPHOSPHATE
CARBOXYLASE SMALL
CHAIN 1
(Rhodobacter
sphaeroides) 		5 / 9 GLN I  22
SER I   9
PHE I   8
LEU I  14
VAL A 429
 None
 1.43A 6ftpA-5nv3I:
undetectable
6ftpB-5nv3I:
undetectable		 6ftpA-5nv3I:
19.49
6ftpB-5nv3I:
14.15