SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nva'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 11 ALA A 392
ILE A 344
GLY A 385
ILE A 386
ILE A 159
None
0.93A 1c6yA-5nvaA:
undetectable
1c6yA-5nvaA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 11 PHE A 150
ILE A 320
GLY A 330
TYR A  17
ALA A 338
None
1.50A 1ju6D-5nvaA:
undetectable
1ju6D-5nvaA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 PHE A 222
LEU A 239
TYR A  83
GLY A  81
ILE A  79
None
None
None
SLB  A 503 (-3.7A)
None
1.14A 1kglA-5nvaA:
undetectable
1kglA-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 GLY A 292
ALA A  71
THR A 215
SER A  66
ILE A 291
None
1.19A 1nt2A-5nvaA:
undetectable
1nt2A-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 ILE A 333
GLY A 330
GLY A 327
PHE A 337
ALA A  12
None
0.91A 1nv8A-5nvaA:
undetectable
1nv8A-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 ILE A 333
GLY A 330
GLY A 327
PHE A 337
ALA A  12
None
0.93A 1nv8B-5nvaA:
undetectable
1nv8B-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 10 ALA A 392
ILE A 344
GLY A 385
ILE A 386
ILE A 159
None
0.91A 1sdvA-5nvaA:
undetectable
1sdvA-5nvaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
4 / 7 ALA A  35
ARG A 362
ASN A 356
GLU A 110
None
1.23A 1t9wA-5nvaA:
undetectable
1t9wA-5nvaA:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 ILE A 333
GLY A 330
GLY A 327
PHE A 337
ALA A  12
None
0.81A 1vq1B-5nvaA:
undetectable
1vq1B-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 MET A 151
LEU A 158
PHE A  15
GLN A 341
PHE A 337
None
1.49A 1xosA-5nvaA:
undetectable
1xosA-5nvaA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 11 ALA A 392
ILE A 344
GLY A 385
ILE A 386
ILE A 159
None
0.83A 2aquB-5nvaA:
undetectable
2aquB-5nvaA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 ALA A 392
ILE A 344
GLY A 385
ILE A 386
ILE A 159
None
0.88A 2nmyA-5nvaA:
undetectable
2nmyA-5nvaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
4 / 7 THR A  57
VAL A 178
VAL A 263
VAL A  45
NA  A 502 ( 4.8A)
NA  A 502 (-4.2A)
None
None
0.96A 2qbnA-5nvaA:
undetectable
2qbnA-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 11 PHE A 131
SER A 468
LEU A 456
ALA A 449
LEU A 413
None
1.33A 2v0mA-5nvaA:
0.0
2v0mA-5nvaA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 9 PHE A 131
SER A 468
LEU A 456
ALA A 449
LEU A 413
None
1.29A 2v0mB-5nvaA:
undetectable
2v0mB-5nvaA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 PRO A 317
VAL A 321
ALA A 338
ALA A 340
THR A 140
None
1.28A 2x2nC-5nvaA:
undetectable
2x2nC-5nvaA:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_B_TC9B1206_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 11 THR A 170
TYR A 169
SER A 346
SER A 345
SER A  53
None
None
NA  A 502 (-2.3A)
NA  A 502 (-2.3A)
None
1.38A 2xytB-5nvaA:
undetectable
2xytC-5nvaA:
undetectable
2xytG-5nvaA:
undetectable
2xytB-5nvaA:
17.89
2xytC-5nvaA:
17.89
2xytG-5nvaA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
4 / 8 THR A 140
GLN A 341
SER A 388
CYH A 166
None
1.12A 2xz5C-5nvaA:
undetectable
2xz5D-5nvaA:
undetectable
2xz5C-5nvaA:
undetectable
2xz5D-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
4 / 6 THR A 264
ILE A 179
SER A  53
THR A 273
None
0.92A 3deuB-5nvaA:
undetectable
3deuB-5nvaA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 ALA A 392
ILE A 344
GLY A 385
ILE A 386
ILE A 159
None
0.88A 3ekqA-5nvaA:
undetectable
3ekqA-5nvaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 10 ALA A 392
ILE A 344
GLY A 385
ILE A 386
ILE A 159
None
0.87A 3ekwA-5nvaA:
undetectable
3ekwA-5nvaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 11 ALA A 392
ILE A 344
GLY A 385
ILE A 386
ILE A 159
None
0.85A 3ekxB-5nvaA:
undetectable
3ekxB-5nvaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
4 / 5 ILE A  88
THR A 419
PHE A 100
TYR A  96
None
1.34A 3em0A-5nvaA:
undetectable
3em0A-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
4 / 7 ILE A 464
PHE A 458
TYR A 461
GLY A 416
None
1.07A 3em0B-5nvaA:
undetectable
3em0B-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 ALA A 392
ILE A 344
GLY A 385
ILE A 386
ILE A 159
None
0.80A 3k4vC-5nvaA:
undetectable
3k4vC-5nvaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 ALA A 392
ILE A 344
GLY A 385
ILE A 386
ILE A 159
None
0.80A 3ndtC-5nvaA:
undetectable
3ndtC-5nvaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
6 / 9 ALA A 392
ILE A 344
GLY A 385
ILE A 386
VAL A 160
ILE A 159
None
1.27A 3ndwB-5nvaA:
undetectable
3ndwB-5nvaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 11 ALA A 392
ILE A 344
GLY A 385
ILE A 386
ILE A 159
None
0.90A 3ndxB-5nvaA:
undetectable
3ndxB-5nvaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 9 ALA A 392
ILE A 162
GLY A 385
ILE A 386
ILE A 159
None
1.03A 3nu4A-5nvaA:
undetectable
3nu4A-5nvaA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 SER A 127
PHE A 123
GLY A 416
GLY A 420
GLY A 415
None
1.14A 3tegA-5nvaA:
undetectable
3tegA-5nvaA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 9 ILE A 381
THR A 170
GLN A  32
GLY A 173
ARG A  44
None
1.40A 4acaB-5nvaA:
undetectable
4acaC-5nvaA:
undetectable
4acaB-5nvaA:
undetectable
4acaC-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 10 ALA A 392
GLY A 385
ILE A 386
VAL A 160
ILE A 159
None
1.01A 4dqcA-5nvaA:
undetectable
4dqcA-5nvaA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
4 / 6 ALA A 436
ALA A 477
PRO A 478
THR A 476
None
1.11A 4dtzB-5nvaA:
undetectable
4dtzB-5nvaA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 GLY A 174
ASP A 182
ILE A 179
VAL A  45
ARG A 260
None
NA  A 502 (-2.1A)
None
None
NA  A 502 ( 4.5A)
1.12A 4dx5B-5nvaA:
undetectable
4dx5B-5nvaA:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
3 / 3 PHE A  28
ASP A  37
ARG A  44
None
0.75A 4eahF-5nvaA:
undetectable
4eahF-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
3 / 3 PHE A  28
ASP A  37
ARG A  44
None
0.75A 4eahG-5nvaA:
undetectable
4eahG-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 11 GLY A 465
ARG A 451
GLN A 249
MET A 418
PHE A 123
None
1.36A 4j4vA-5nvaA:
undetectable
4j4vA-5nvaA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_E_SVRE301_1
(NUCLEOCAPSID PROTEIN)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 10 GLY A 465
ARG A 451
GLN A 249
MET A 418
PHE A 123
None
1.32A 4j4vA-5nvaA:
undetectable
4j4vE-5nvaA:
0.0
4j4vA-5nvaA:
15.92
4j4vE-5nvaA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 GLY A 412
GLY A 415
LEU A 130
SER A 127
HIS A 132
None
1.03A 4krhA-5nvaA:
undetectable
4krhA-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 GLY A 412
GLY A 415
LEU A 130
SER A 127
HIS A 132
None
1.02A 4krhB-5nvaA:
undetectable
4krhB-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 11 ALA A 392
ILE A 344
GLY A 385
ILE A 386
ILE A 159
None
0.87A 4njtC-5nvaA:
undetectable
4njtC-5nvaA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 12 GLY A 174
ASP A 182
ILE A 179
VAL A  45
ARG A 260
None
NA  A 502 (-2.1A)
None
None
NA  A 502 ( 4.5A)
1.11A 4u95B-5nvaA:
1.7
4u95B-5nvaA:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 11 LEU A 239
PHE A 243
GLN A  82
THR A  63
ILE A  62
None
SLB  A 503 (-3.6A)
SLB  A 503 (-3.1A)
SLB  A 503 (-3.0A)
SLB  A 503 (-3.5A)
1.40A 4uuuA-5nvaA:
undetectable
4uuuB-5nvaA:
undetectable
4uuuA-5nvaA:
undetectable
4uuuB-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
4 / 6 GLY A  51
THR A 273
SER A  53
VAL A  54
None
1.13A 5ewuA-5nvaA:
undetectable
5ewuA-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
4 / 5 MET A 467
SER A 468
VAL A 469
GLY A 420
None
1.02A 5k50A-5nvaA:
undetectable
5k50A-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 10 GLY A 173
GLY A 177
ILE A 167
SER A 345
LEU A 348
None
None
None
NA  A 502 (-2.3A)
None
0.90A 5l0zB-5nvaA:
undetectable
5l0zB-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 10 GLY A 174
GLY A 177
ILE A 167
SER A 345
LEU A 348
None
None
None
NA  A 502 (-2.3A)
None
0.99A 5l0zB-5nvaA:
undetectable
5l0zB-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
4 / 6 GLU A 113
ARG A 121
LEU A 122
ARG A 362
None
0.98A 5l6eA-5nvaA:
undetectable
5l6eB-5nvaA:
undetectable
5l6eA-5nvaA:
undetectable
5l6eB-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AY6_A_VORA501_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 9 TYR A 169
ALA A 338
ALA A 340
THR A 140
LEU A 161
None
1.49A 6ay6A-5nvaA:
undetectable
6ay6A-5nvaA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 10 ALA A 392
ILE A 344
GLY A 385
ILE A 386
ILE A 159
None
0.97A 6dj2A-5nvaA:
undetectable
6dj2A-5nvaA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 11 ASP A 358
SER A 357
VAL A 258
SER A  53
ALA A  49
None
1.03A 6hu9A-5nvaA:
undetectable
6hu9E-5nvaA:
undetectable
6hu9I-5nvaA:
undetectable
6hu9A-5nvaA:
undetectable
6hu9E-5nvaA:
undetectable
6hu9I-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 11 SER A 107
VAL A 380
GLY A 385
SER A 388
ALA A 391
None
1.38A 6hu9A-5nvaA:
undetectable
6hu9E-5nvaA:
undetectable
6hu9I-5nvaA:
undetectable
6hu9A-5nvaA:
undetectable
6hu9E-5nvaA:
undetectable
6hu9I-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 10 ASP A 358
SER A 357
VAL A 258
SER A  53
ALA A  49
None
1.07A 6hu9L-5nvaA:
undetectable
6hu9P-5nvaA:
undetectable
6hu9T-5nvaA:
undetectable
6hu9L-5nvaA:
undetectable
6hu9P-5nvaA:
undetectable
6hu9T-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis)
5 / 10 SER A 107
VAL A 380
GLY A 385
SER A 388
ALA A 391
None
1.40A 6hu9L-5nvaA:
undetectable
6hu9P-5nvaA:
undetectable
6hu9T-5nvaA:
undetectable
6hu9L-5nvaA:
undetectable
6hu9P-5nvaA:
undetectable
6hu9T-5nvaA:
undetectable