SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nxf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 5nxf LONG-TAIL FIBER
PROXIMAL SUBUNIT
(Escherichia
virus
T4) 		4 / 5 LEU A1134
ASP A1133
LEU A1191
THR A1143
 None
 1.15A 4wozF-5nxfA:
undetectable
4wozH-5nxfA:
undetectable		 4wozF-5nxfA:
19.73
4wozH-5nxfA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 5nxf LONG-TAIL FIBER
PROXIMAL SUBUNIT
(Escherichia
virus
T4) 		4 / 6 GLY A 843
THR A 850
GLN A 851
TYR A 856
 None
 0.93A 6ag0C-5nxfA:
undetectable		 6ag0C-5nxfA:
10.52