SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nxn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 12 LEU A 184
GLY A 191
TYR A 182
SER A 149
ALA A 241
 None
 1.10A 2bm9D-5nxnA:
undetectable		 2bm9D-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 5nxn PORIN 1
(Providencia
stuartii) 		3 / 3 ASN A 172
TYR A 154
SER A 198
 None
 0.94A 2gvcE-5nxnA:
undetectable		 2gvcE-5nxnA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 5nxn PORIN 1
(Providencia
stuartii) 		4 / 6 ARG A 137
ASP A  93
THR A 135
ASP A 103
 None
 0.93A 2j2pE-5nxnA:
undetectable
2j2pF-5nxnA:
undetectable		 2j2pE-5nxnA:
17.43
2j2pF-5nxnA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 5nxn PORIN 1
(Providencia
stuartii) 		4 / 6 TYR A  81
ALA A  80
LEU A  79
THR A 122
 None
 0.93A 3b6hB-5nxnA:
undetectable		 3b6hB-5nxnA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 5nxn PORIN 1
(Providencia
stuartii) 		4 / 5 VAL A 101
VAL A 100
THR A 249
THR A 104
 None
 1.16A 3bjwA-5nxnA:
undetectable		 3bjwA-5nxnA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 5nxn PORIN 1
(Providencia
stuartii) 		4 / 5 VAL A 101
VAL A 100
THR A 249
THR A 104
 None
 1.17A 3bjwC-5nxnA:
undetectable		 3bjwC-5nxnA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 5nxn PORIN 1
(Providencia
stuartii) 		4 / 5 VAL A 101
VAL A 100
THR A 249
THR A 104
 None
 1.12A 3bjwD-5nxnA:
undetectable		 3bjwD-5nxnA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 12 GLY A 253
ILE A 258
ALA A 169
MET A 168
GLU A 335
 None
 1.09A 3ckkA-5nxnA:
undetectable		 3ckkA-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 5nxn PORIN 1
(Providencia
stuartii) 		3 / 3 LYS A  16
ARG A  20
LYS A 278
 None
 1.32A 3okxA-5nxnA:
undetectable		 3okxA-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 12 GLY A 193
GLY A 177
SER A 195
LEU A 152
ALA A 181
 None
 1.00A 3ou6A-5nxnA:
undetectable		 3ou6A-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 12 GLY A 193
GLY A 177
SER A 195
LEU A 152
ALA A 181
 None
 1.01A 3ou6B-5nxnA:
undetectable		 3ou6B-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 12 GLY A 193
GLY A 177
SER A 195
LEU A 152
ALA A 181
 None
 1.02A 3ou7B-5nxnA:
undetectable		 3ou7B-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 12 TYR A 243
GLY A 244
ASN A 105
ALA A 259
LEU A 300
 None
 1.02A 3vywA-5nxnA:
undetectable		 3vywA-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 12 TYR A 295
TYR A 252
GLY A 337
GLY A 253
PHE A 332
 None
 0.76A 3vywA-5nxnA:
undetectable		 3vywA-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 12 TYR A 243
GLY A 244
ASN A 105
ALA A 259
LEU A 300
 None
 1.04A 3vywB-5nxnA:
undetectable		 3vywB-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 12 TYR A 243
GLY A 244
ASN A 105
ALA A 259
LEU A 300
 None
 0.97A 3vywD-5nxnA:
undetectable		 3vywD-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 12 TYR A 295
TYR A 252
GLY A 337
GLY A 253
PHE A 332
 None
 0.73A 3vywD-5nxnA:
undetectable		 3vywD-5nxnA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 5nxn PORIN 1
(Providencia
stuartii) 		4 / 8 ARG A  20
ARG A  41
ASP A 109
ARG A  78
 None
 1.41A 4kr4C-5nxnA:
38.0		 4kr4C-5nxnA:
48.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 5nxn PORIN 1
(Providencia
stuartii) 		4 / 8 LYS A  16
ARG A  20
ARG A  78
ARG A 129
 None
 1.17A 4kr4C-5nxnA:
38.0		 4kr4C-5nxnA:
48.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 5nxn PORIN 1
(Providencia
stuartii) 		4 / 8 LYS A  16
ARG A  20
ASP A 109
ARG A 129
 None
 1.15A 4kr4C-5nxnA:
38.0		 4kr4C-5nxnA:
48.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KR8_C_DM1C401_1
(OUTER MEMBRANE
PROTEIN F)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 10 LYS A  16
ARG A  20
ARG A  78
TYR A  98
ARG A 129
 None
 1.08A 4kr8C-5nxnA:
40.3		 4kr8C-5nxnA:
48.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KR8_C_DM1C401_1
(OUTER MEMBRANE
PROTEIN F)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 10 LYS A  16
ARG A  78
TYR A  98
THR A 122
ARG A 129
 None
 0.62A 4kr8C-5nxnA:
40.3		 4kr8C-5nxnA:
48.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5nxn PORIN 1
(Providencia
stuartii) 		4 / 4 ASN A 284
GLY A 115
ASP A  34
ASP A 321
 None
 1.07A 4n49A-5nxnA:
undetectable		 4n49A-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 12 ARG A 137
ALA A 151
SER A 179
GLY A 177
TYR A  81
 None
 1.30A 4r29A-5nxnA:
undetectable		 4r29A-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5nxn PORIN 1
(Providencia
stuartii) 		4 / 6 TYR A 295
ASN A 330
GLU A 335
TYR A 252
 None
 1.36A 4twdG-5nxnA:
undetectable
4twdH-5nxnA:
undetectable		 4twdG-5nxnA:
13.31
4twdH-5nxnA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ5_B_ACTB404_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 5nxn PORIN 1
(Providencia
stuartii) 		3 / 3 TYR A  14
ARG A  59
LYS A  45
 None
 1.27A 4wq5B-5nxnA:
undetectable		 4wq5B-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5nxn PORIN 1
(Providencia
stuartii) 		3 / 3 ASP A  37
ARG A 129
ARG A  41
 None
 0.94A 4x5iA-5nxnA:
undetectable		 4x5iA-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 5nxn PORIN 1
(Providencia
stuartii) 		4 / 5 GLY A  83
TYR A 136
SER A  91
ASP A  93
 None
 1.35A 4xueA-5nxnA:
undetectable		 4xueA-5nxnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 5nxn PORIN 1
(Providencia
stuartii) 		5 / 12 GLY A  83
TYR A 136
SER A  91
ASP A  93
ALA A  82
 None
 1.38A 4ymgB-5nxnA:
undetectable		 4ymgB-5nxnA:
undetectable