SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ny0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 6 LEU A 274
ILE A 364
TYR A 306
VAL A 349
None
1.03A 1db1A-5ny0A:
undetectable
1db1A-5ny0A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 7 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.74A 1v54N-5ny0A:
undetectable
1v54W-5ny0A:
undetectable
1v54N-5ny0A:
undetectable
1v54W-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 THR A 474
LEU A 475
ILE A 441
VAL A 389
LEU A 467
None
1.32A 1wsvA-5ny0A:
undetectable
1wsvA-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 THR A 474
LEU A 475
ILE A 441
VAL A 389
LEU A 467
None
1.32A 1wsvB-5ny0A:
undetectable
1wsvB-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 6 ALA A 509
SER A 483
ASN A 486
ILE A 487
ASP A 451
None
1.26A 1yc2A-5ny0A:
undetectable
1yc2A-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 7 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.78A 2dyrN-5ny0A:
undetectable
2dyrW-5ny0A:
undetectable
2dyrN-5ny0A:
undetectable
2dyrW-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 8 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.78A 2eijN-5ny0A:
undetectable
2eijW-5ny0A:
undetectable
2eijN-5ny0A:
undetectable
2eijW-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 8 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.78A 2eikN-5ny0A:
undetectable
2eikW-5ny0A:
undetectable
2eikN-5ny0A:
undetectable
2eikW-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 8 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.77A 2eilN-5ny0A:
undetectable
2eilW-5ny0A:
undetectable
2eilN-5ny0A:
undetectable
2eilW-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 6 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.74A 2einN-5ny0A:
undetectable
2einW-5ny0A:
undetectable
2einN-5ny0A:
undetectable
2einW-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 VAL A 527
PHE A 529
THR A 468
VAL A 535
LEU A 537
None
1.23A 2jn3A-5ny0A:
undetectable
2jn3A-5ny0A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 PRO A 425
THR A 370
GLY A 369
GLY A 368
THR A 406
None
1.02A 2uvnA-5ny0A:
undetectable
2uvnA-5ny0A:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 ILE A 294
ALA A 273
LEU A 284
ILE A 335
LEU A 340
None
1.14A 2zzaA-5ny0A:
undetectable
2zzaA-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 11 ILE A 294
ALA A 273
LEU A 284
ILE A 335
LEU A 340
None
1.13A 2zzaB-5ny0A:
undetectable
2zzaB-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 ILE A 294
LEU A 290
ILE A 282
VAL A 331
LEU A 333
None
1.12A 3a51C-5ny0A:
undetectable
3a51C-5ny0A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 7 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.81A 3ablA-5ny0A:
undetectable
3ablJ-5ny0A:
undetectable
3ablA-5ny0A:
undetectable
3ablJ-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 8 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.78A 3ablN-5ny0A:
undetectable
3ablW-5ny0A:
undetectable
3ablN-5ny0A:
undetectable
3ablW-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 6 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.69A 3ag1N-5ny0A:
undetectable
3ag1W-5ny0A:
undetectable
3ag1N-5ny0A:
undetectable
3ag1W-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 8 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.77A 3ag3N-5ny0A:
undetectable
3ag3W-5ny0A:
undetectable
3ag3N-5ny0A:
undetectable
3ag3W-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 8 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.80A 3asnN-5ny0A:
undetectable
3asnW-5ny0A:
undetectable
3asnN-5ny0A:
undetectable
3asnW-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
3 / 3 ASN A 513
MET A 454
PHE A 497
None
1.16A 3g4lD-5ny0A:
undetectable
3g4lD-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_1
(DIHYDROFOLATE
REDUCTASE)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 ILE A 294
ALA A 273
LEU A 284
ILE A 335
LEU A 340
None
1.05A 3ia4B-5ny0A:
undetectable
3ia4B-5ny0A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_1
(DIHYDROFOLATE
REDUCTASE)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 ILE A 294
ALA A 273
LEU A 284
ILE A 335
LEU A 340
None
1.08A 3ia4D-5ny0A:
undetectable
3ia4D-5ny0A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 ASN A 342
LEU A 371
THR A 382
LEU A 383
TRP A 373
None
1.14A 3p2kB-5ny0A:
undetectable
3p2kB-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
3 / 3 ASN A 445
ALA A 447
LYS A 449
None
0.93A 3runA-5ny0A:
undetectable
3runA-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 6 ASP A 586
GLY A 542
VAL A 511
ASP A 512
None
1.22A 3vqrA-5ny0A:
undetectable
3vqrA-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 5 ASP A 586
GLY A 542
VAL A 511
ASP A 512
None
1.22A 3vqrB-5ny0A:
undetectable
3vqrB-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 6 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.83A 3wg7N-5ny0A:
undetectable
3wg7W-5ny0A:
undetectable
3wg7N-5ny0A:
undetectable
3wg7W-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 LEU A 333
VAL A 331
ILE A 323
ILE A 321
ALA A 293
None
1.03A 4ltwA-5ny0A:
undetectable
4ltwA-5ny0A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 GLY A 347
GLY A 319
ASN A 318
ALA A 447
ALA A 408
None
0.94A 4uciA-5ny0A:
undetectable
4uciA-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 GLY A 347
GLY A 319
ASN A 318
ALA A 447
ALA A 408
None
0.94A 4uciB-5ny0A:
undetectable
4uciB-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 GLY A 347
GLY A 319
ASN A 318
ALA A 447
ALA A 408
None
0.95A 4uckA-5ny0A:
undetectable
4uckA-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 GLY A 347
GLY A 319
ASN A 318
ALA A 447
ALA A 408
None
0.95A 4uckB-5ny0A:
undetectable
4uckB-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 12 LEU A 296
ILE A 335
ILE A 305
VAL A 372
LEU A 383
None
1.26A 4y0pA-5ny0A:
undetectable
4y0pA-5ny0A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 4 VAL A 609
ILE A 555
ASN A 544
VAL A 620
None
1.09A 5ajqA-5ny0A:
undetectable
5ajqA-5ny0A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 7 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.80A 5b1bA-5ny0A:
undetectable
5b1bJ-5ny0A:
undetectable
5b1bA-5ny0A:
undetectable
5b1bJ-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 7 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.82A 5b1bN-5ny0A:
undetectable
5b1bW-5ny0A:
undetectable
5b1bN-5ny0A:
undetectable
5b1bW-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 7 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.81A 5b3sN-5ny0A:
undetectable
5b3sW-5ny0A:
undetectable
5b3sN-5ny0A:
undetectable
5b3sW-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 7 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.78A 5iy5A-5ny0A:
undetectable
5iy5J-5ny0A:
undetectable
5iy5A-5ny0A:
undetectable
5iy5J-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 7 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.80A 5iy5N-5ny0A:
undetectable
5iy5W-5ny0A:
undetectable
5iy5N-5ny0A:
undetectable
5iy5W-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 10 ALA A 473
THR A 474
SER A 503
GLY A 387
ALA A 436
None
1.38A 5l66K-5ny0A:
undetectable
5l66L-5ny0A:
undetectable
5l66K-5ny0A:
18.38
5l66L-5ny0A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 10 ALA A 473
THR A 474
SER A 503
GLY A 387
ALA A 436
None
1.39A 5l66Y-5ny0A:
undetectable
5l66Z-5ny0A:
undetectable
5l66Y-5ny0A:
18.38
5l66Z-5ny0A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
5 / 9 GLY A 307
LEU A 284
ILE A 312
LEU A 340
ILE A 323
None
0.92A 5vkqC-5ny0A:
undetectable
5vkqD-5ny0A:
undetectable
5vkqC-5ny0A:
undetectable
5vkqD-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 8 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.81A 5xdxN-5ny0A:
undetectable
5xdxW-5ny0A:
undetectable
5xdxN-5ny0A:
undetectable
5xdxW-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 6 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.80A 5z86N-5ny0A:
undetectable
5z86W-5ny0A:
undetectable
5z86N-5ny0A:
undetectable
5z86W-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 8 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.79A 5zcoA-5ny0A:
undetectable
5zcoJ-5ny0A:
undetectable
5zcoA-5ny0A:
undetectable
5zcoJ-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 6 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.80A 5zcoN-5ny0A:
undetectable
5zcoW-5ny0A:
undetectable
5zcoN-5ny0A:
undetectable
5zcoW-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 8 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.83A 5zcqN-5ny0A:
undetectable
5zcqW-5ny0A:
undetectable
5zcqN-5ny0A:
undetectable
5zcqW-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 7 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.69A 6nmfA-5ny0A:
undetectable
6nmfJ-5ny0A:
undetectable
6nmfA-5ny0A:
undetectable
6nmfJ-5ny0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5ny0 L. REUTERIS SRRP
BINDING REGION

(Lactobacillus
reuteri)
4 / 7 ILE A 427
MET A 477
THR A 476
LEU A 475
None
0.69A 6nmpA-5ny0A:
undetectable
6nmpJ-5ny0A:
undetectable
6nmpA-5ny0A:
undetectable
6nmpJ-5ny0A:
undetectable