SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5nyj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		3 / 3 ALA A  93
VAL A  59
TRP A  36
 None
 0.89A 1av2C-5nyjA:
undetectable
1av2D-5nyjA:
undetectable		 1av2C-5nyjA:
4.44
1av2D-5nyjA:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 10 THR A   1
GLY A 151
HIS A 153
VAL A 191
ILE A 117
 None
 1.10A 1likA-5nyjA:
undetectable		 1likA-5nyjA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		6 / 11 THR A   1
THR A  20
ALA A  28
LYS A  32
GLY A  50
SER A 190
 None
 1.27A 2f162-5nyjA:
21.5		 2f162-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
ALA A  28
LYS A  32
ALA A  49
GLY A  50
 None
 1.09A 2f16H-5nyjA:
9.7
2f16I-5nyjA:
20.9		 2f16H-5nyjA:
25.19
2f16I-5nyjA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		6 / 11 THR A   1
THR A  20
ALA A  28
LYS A  32
GLY A  50
SER A 190
 None
 1.28A 2f16N-5nyjA:
21.5		 2f16N-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
ALA A  28
LYS A  32
ALA A  49
GLY A  50
 None
 1.09A 2f16V-5nyjA:
5.3
2f16W-5nyjA:
20.9		 2f16V-5nyjA:
25.19
2f16W-5nyjA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		4 / 8 GLY A 156
ILE A 213
VAL A  13
SER A 183
 None
 0.77A 2yoeB-5nyjA:
undetectable
2yoeC-5nyjA:
undetectable		 2yoeB-5nyjA:
21.20
2yoeC-5nyjA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 12 GLY A 124
ILE A 122
ASP A 203
ARG A 202
ARG A 126
 None
 1.16A 3iv6D-5nyjA:
undetectable		 3iv6D-5nyjA:
27.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		6 / 12 THR A   1
THR A  20
ALA A  28
LYS A  32
GLY A  50
SER A 190
 None
 1.29A 3mg02-5nyjA:
21.6
3mg0V-5nyjA:
5.7		 3mg02-5nyjA:
24.15
3mg0V-5nyjA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		6 / 11 THR A   1
THR A  20
ALA A  28
LYS A  32
GLY A  50
SER A 190
 None
 1.30A 3mg0N-5nyjA:
21.4		 3mg0N-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
ALA A  28
LYS A  32
ALA A  49
GLY A  50
 None
 1.15A 3mg0V-5nyjA:
5.7
3mg0W-5nyjA:
20.9		 3mg0V-5nyjA:
25.19
3mg0W-5nyjA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 LEU A 160
TYR A   2
ILE A 117
PHE A   6
LEU A 129
 None
 1.34A 4lhmA-5nyjA:
undetectable		 4lhmA-5nyjA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 12 GLY A 119
ILE A 132
ILE A 122
ALA A  86
ARG A  95
 None
 1.14A 4qtuB-5nyjA:
undetectable		 4qtuB-5nyjA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.88A 4qvlV-5nyjA:
5.7
4qvlb-5nyjA:
21.5		 4qvlV-5nyjA:
26.89
4qvlb-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.88A 4qvlH-5nyjA:
7.2
4qvlN-5nyjA:
21.6		 4qvlH-5nyjA:
26.89
4qvlN-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.86A 4qvmV-5nyjA:
5.8
4qvmb-5nyjA:
21.6		 4qvmV-5nyjA:
26.89
4qvmb-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.87A 4qvmH-5nyjA:
7.2
4qvmN-5nyjA:
21.6		 4qvmH-5nyjA:
26.89
4qvmN-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		6 / 12 THR A   1
THR A  20
ALA A  28
LYS A  32
GLY A  50
THR A  55
 None
 1.17A 4qvnV-5nyjA:
5.7
4qvnb-5nyjA:
21.6		 4qvnV-5nyjA:
26.89
4qvnb-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		6 / 12 THR A   1
THR A  20
ALA A  28
LYS A  32
GLY A  50
THR A  55
 None
 1.17A 4qvnH-5nyjA:
9.2
4qvnN-5nyjA:
21.6		 4qvnH-5nyjA:
26.89
4qvnN-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.85A 4qvpV-5nyjA:
5.8
4qvpb-5nyjA:
21.6		 4qvpV-5nyjA:
26.89
4qvpb-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.84A 4qvpH-5nyjA:
7.2
4qvpN-5nyjA:
21.6		 4qvpH-5nyjA:
26.89
4qvpN-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.85A 4qvqV-5nyjA:
5.8
4qvqb-5nyjA:
21.6		 4qvqV-5nyjA:
26.89
4qvqb-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.85A 4qvqH-5nyjA:
7.2
4qvqN-5nyjA:
21.6		 4qvqH-5nyjA:
26.89
4qvqN-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.89A 4qvwV-5nyjA:
5.8
4qvwb-5nyjA:
21.6		 4qvwV-5nyjA:
26.89
4qvwb-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.89A 4qvwH-5nyjA:
7.2
4qvwN-5nyjA:
21.6		 4qvwH-5nyjA:
26.89
4qvwN-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.90A 4qw0V-5nyjA:
5.8
4qw0b-5nyjA:
21.6		 4qw0V-5nyjA:
26.89
4qw0b-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.90A 4qw0H-5nyjA:
7.2
4qw0N-5nyjA:
21.6		 4qw0H-5nyjA:
26.89
4qw0N-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.86A 4qw1V-5nyjA:
5.7
4qw1b-5nyjA:
21.6		 4qw1V-5nyjA:
26.89
4qw1b-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.86A 4qw1H-5nyjA:
9.7
4qw1N-5nyjA:
21.5		 4qw1H-5nyjA:
26.89
4qw1N-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.88A 4qw3V-5nyjA:
5.9
4qw3b-5nyjA:
21.7		 4qw3V-5nyjA:
26.89
4qw3b-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.88A 4qw3H-5nyjA:
7.2
4qw3N-5nyjA:
21.7		 4qw3H-5nyjA:
26.89
4qw3N-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.85A 4qwuV-5nyjA:
5.7
4qwub-5nyjA:
21.5		 4qwuV-5nyjA:
26.89
4qwub-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.85A 4qwuH-5nyjA:
9.6
4qwuN-5nyjA:
21.4		 4qwuH-5nyjA:
26.89
4qwuN-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.86A 5bxnV-5nyjA:
4.7
5bxnb-5nyjA:
21.6		 5bxnV-5nyjA:
26.89
5bxnb-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.86A 5bxnH-5nyjA:
19.9
5bxnN-5nyjA:
21.5		 5bxnH-5nyjA:
26.89
5bxnN-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.87A 5cz7H-5nyjA:
19.8
5cz7N-5nyjA:
21.6		 5cz7H-5nyjA:
26.89
5cz7N-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.89A 5d0xV-5nyjA:
5.8
5d0xb-5nyjA:
21.6		 5d0xV-5nyjA:
26.89
5d0xb-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.87A 5d0xH-5nyjA:
7.2
5d0xN-5nyjA:
21.6		 5d0xH-5nyjA:
26.89
5d0xN-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		4 / 6 PHE A   6
MET A 177
LEU A  12
LEU A   8
 None
 1.20A 5dzke-5nyjA:
undetectable
5dzks-5nyjA:
undetectable		 5dzke-5nyjA:
23.66
5dzks-5nyjA:
1.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 12 ALA A   3
PHE A 181
GLY A 156
GLU A 152
TYR A 155
 None
 1.32A 5hfjA-5nyjA:
undetectable		 5hfjA-5nyjA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 12 ALA A   3
PHE A 181
GLY A 156
GLU A 152
TYR A 155
 None
 1.31A 5hfjG-5nyjA:
undetectable		 5hfjG-5nyjA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 12 ASP A 182
PHE A 181
GLY A 156
GLU A 152
TYR A 155
 None
 1.25A 5hfjG-5nyjA:
undetectable		 5hfjG-5nyjA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 12 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.83A 5l5zV-5nyjA:
5.8
5l5zb-5nyjA:
21.7		 5l5zV-5nyjA:
26.89
5l5zb-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 12 THR A   1
LYS A  32
ALA A  49
GLY A  50
THR A  55
 None
 0.75A 5l5zH-5nyjA:
9.2
5l5zI-5nyjA:
21.1		 5l5zH-5nyjA:
26.89
5l5zI-5nyjA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 12 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.84A 5l5zH-5nyjA:
7.2
5l5zN-5nyjA:
21.7		 5l5zH-5nyjA:
26.89
5l5zN-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 12 THR A   1
LYS A  32
ALA A  49
GLY A  50
THR A  55
 None
 0.74A 5l5zV-5nyjA:
6.2
5l5zW-5nyjA:
21.1		 5l5zV-5nyjA:
26.89
5l5zW-5nyjA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.83A 5l66V-5nyjA:
5.8
5l66b-5nyjA:
21.7		 5l66V-5nyjA:
26.89
5l66b-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 11 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.83A 5l66H-5nyjA:
7.2
5l66N-5nyjA:
21.7		 5l66H-5nyjA:
26.89
5l66N-5nyjA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		6 / 12 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
SER A 190
 None
 1.11A 5lf3b-5nyjA:
21.6		 5lf3b-5nyjA:
26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		6 / 12 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
SER A 190
 None
 1.11A 5lf3N-5nyjA:
21.6		 5lf3N-5nyjA:
26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 10 THR A   1
LYS A  32
ALA A  49
GLY A  50
THR A  55
 None
 0.70A 5lf3V-5nyjA:
20.6
5lf3W-5nyjA:
20.9		 5lf3V-5nyjA:
26.12
5lf3W-5nyjA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 12 THR A   1
THR A  20
LYS A  32
GLY A  50
THR A  55
 None
 0.86A 5lf7V-5nyjA:
20.5
5lf7b-5nyjA:
21.5		 5lf7V-5nyjA:
26.12
5lf7b-5nyjA:
26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		5 / 12 THR A  20
ALA A  28
LYS A  32
GLY A  50
THR A  55
 None
 1.06A 5lf7V-5nyjA:
20.5
5lf7b-5nyjA:
21.5		 5lf7V-5nyjA:
26.12
5lf7b-5nyjA:
26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		6 / 12 THR A   1
THR A  20
ALA A  28
LYS A  32
GLY A  50
THR A  55
 None
 1.12A 5lf7H-5nyjA:
20.6
5lf7N-5nyjA:
21.5		 5lf7H-5nyjA:
26.12
5lf7N-5nyjA:
26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		4 / 8 SER A 224
ARG A 186
ASN A 225
ASP A 229
 None
 1.32A 5vunB-5nyjA:
undetectable		 5vunB-5nyjA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		6 / 12 THR A   1
THR A  20
ALA A  28
LYS A  32
GLY A  50
THR A  55
 None
 1.14A 6hwdV-5nyjA:
5.8
6hwdb-5nyjA:
21.6		 6hwdV-5nyjA:
15.52
6hwdb-5nyjA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		6 / 12 THR A   1
ALA A  28
LYS A  32
ALA A  49
GLY A  50
THR A  55
 None
 1.09A 6hwdH-5nyjA:
19.7
6hwdI-5nyjA:
20.9		 6hwdH-5nyjA:
15.52
6hwdI-5nyjA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		6 / 12 THR A   1
THR A  20
ALA A  28
LYS A  32
GLY A  50
THR A  55
 None
 1.14A 6hwdH-5nyjA:
19.8
6hwdN-5nyjA:
21.6		 6hwdH-5nyjA:
15.52
6hwdN-5nyjA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5nyj ANBU
(Hyphomicrobium
sp.
MC1) 		6 / 11 THR A   1
ALA A  28
LYS A  32
ALA A  49
GLY A  50
THR A  55
 None
 1.09A 6hwdV-5nyjA:
6.1		 6hwdV-5nyjA:
15.52