SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o0d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 5o0d PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 12 LEU A 152
VAL A 148
VAL A  13
ARG A  50
GLY A  43
 None
 1.16A 2cbrA-5o0dA:
undetectable		 2cbrA-5o0dA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 5o0d PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 12 GLY A  16
HIS A  17
GLY A  88
ASP A  94
THR A 118
 None
 1.08A 5hg0B-5o0dA:
8.4		 5hg0B-5o0dA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 5o0d PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacteroides
abscessus) 		6 / 12 ALA A  34
GLU A  30
LEU A  64
VAL A  86
ASP A  29
PHE A  28
 None
 1.47A 5vlmG-5o0dA:
undetectable		 5vlmG-5o0dA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5o0d PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 6 GLY A 137
TYR A 136
LEU A 153
VAL A 140
 None
 0.83A 5x80A-5o0dA:
undetectable
5x80B-5o0dA:
undetectable		 5x80A-5o0dA:
28.57
5x80B-5o0dA:
28.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5o0d PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacteroides
abscessus) 		4 / 5 GLY A   8
HIS A  17
SER A 126
SER A 127
 None
 0.30A 6jmjA-5o0dA:
25.7		 6jmjA-5o0dA:
39.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5o0d PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacteroides
abscessus) 		6 / 7 GLY A   8
PHE A  10
HIS A  17
ARG A  90
SER A 126
SER A 127
 None
 0.37A 6jnhA-5o0dA:
25.7		 6jnhA-5o0dA:
39.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5o0d PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacteroides
abscessus) 		5 / 6 GLY A   8
HIS A  17
ARG A  90
SER A 126
SER A 127
 None
 0.45A 6jogA-5o0dA:
25.6		 6jogA-5o0dA:
39.16