SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o0l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 6 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
1.04A 1v54A-5o0lA:
undetectable
1v54J-5o0lA:
undetectable
1v54A-5o0lA:
20.26
1v54J-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 7 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
0.95A 1v54N-5o0lA:
undetectable
1v54W-5o0lA:
undetectable
1v54N-5o0lA:
20.26
1v54W-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 7 LEU A 228
ASP A 205
THR A 181
HIS A 136
None
1.19A 1v55C-5o0lA:
undetectable
1v55N-5o0lA:
undetectable
1v55P-5o0lA:
undetectable
1v55C-5o0lA:
23.01
1v55N-5o0lA:
20.26
1v55P-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 6 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
0.96A 2dysN-5o0lA:
undetectable
2dysW-5o0lA:
undetectable
2dysN-5o0lA:
20.26
2dysW-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 6 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
1.04A 2eijA-5o0lA:
undetectable
2eijJ-5o0lA:
undetectable
2eijA-5o0lA:
20.26
2eijJ-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
0.91A 2eijN-5o0lA:
undetectable
2eijW-5o0lA:
undetectable
2eijN-5o0lA:
20.26
2eijW-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 7 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
1.00A 2eikA-5o0lA:
undetectable
2eikJ-5o0lA:
undetectable
2eikA-5o0lA:
20.26
2eikJ-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
0.92A 2eikN-5o0lA:
undetectable
2eikW-5o0lA:
undetectable
2eikN-5o0lA:
20.26
2eikW-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 6 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
1.01A 2eilA-5o0lA:
undetectable
2eilJ-5o0lA:
undetectable
2eilA-5o0lA:
20.26
2eilJ-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
5 / 11 LEU A  83
LEU A 107
LEU A 129
ILE A  62
VAL A  72
None
1.07A 2qd3A-5o0lA:
undetectable
2qd3A-5o0lA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
5 / 11 LEU A 112
LEU A 137
LEU A 159
ILE A  96
THR A 173
None
1.30A 2qd3A-5o0lA:
undetectable
2qd3A-5o0lA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 LEU A 228
ASP A 205
THR A 181
HIS A 136
None
1.20A 2y69C-5o0lA:
undetectable
2y69N-5o0lA:
undetectable
2y69P-5o0lA:
undetectable
2y69C-5o0lA:
23.01
2y69N-5o0lA:
20.26
2y69P-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 6 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
1.08A 3asnA-5o0lA:
undetectable
3asnJ-5o0lA:
undetectable
3asnA-5o0lA:
20.26
3asnJ-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 LEU A 228
ASP A 205
THR A 181
HIS A 136
None
1.16A 3asnC-5o0lA:
undetectable
3asnN-5o0lA:
undetectable
3asnP-5o0lA:
undetectable
3asnC-5o0lA:
23.01
3asnN-5o0lA:
20.26
3asnP-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
0.95A 3asnN-5o0lA:
undetectable
3asnW-5o0lA:
undetectable
3asnN-5o0lA:
20.26
3asnW-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 ASP A 205
THR A 181
HIS A 136
LEU A 228
None
1.18A 3asoA-5o0lA:
undetectable
3asoC-5o0lA:
undetectable
3asoP-5o0lA:
undetectable
3asoA-5o0lA:
20.26
3asoC-5o0lA:
23.01
3asoP-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 LEU A 228
ASP A 205
THR A 181
HIS A 136
None
1.17A 3asoC-5o0lA:
undetectable
3asoN-5o0lA:
undetectable
3asoP-5o0lA:
undetectable
3asoC-5o0lA:
23.01
3asoN-5o0lA:
20.26
3asoP-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 7 THR A 125
LEU A 135
LEU A 112
LEU A 110
None
0.79A 3bgdB-5o0lA:
undetectable
3bgdB-5o0lA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 7 THR A 173
LEU A 183
LEU A 161
LEU A 159
None
0.88A 3bgdB-5o0lA:
undetectable
3bgdB-5o0lA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 7 THR A 173
LEU A 185
LEU A 166
LEU A 161
None
0.88A 3bgdB-5o0lA:
undetectable
3bgdB-5o0lA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
5 / 12 LEU A 110
LEU A 129
PRO A  56
THR A  40
THR A  84
None
1.19A 3dcjA-5o0lA:
undetectable
3dcjB-5o0lA:
undetectable
3dcjA-5o0lA:
23.81
3dcjB-5o0lA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
5 / 10 LEU A 142
ILE A  96
LEU A 112
PHE A 126
THR A 173
None
1.14A 3jw5B-5o0lA:
undetectable
3jw5B-5o0lA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 ASP A 205
THR A 181
HIS A 136
LEU A 228
None
1.20A 3wg7A-5o0lA:
undetectable
3wg7C-5o0lA:
undetectable
3wg7P-5o0lA:
undetectable
3wg7A-5o0lA:
20.26
3wg7C-5o0lA:
23.01
3wg7P-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 LEU A 228
ASP A 205
THR A 181
HIS A 136
None
1.21A 3wg7C-5o0lA:
undetectable
3wg7N-5o0lA:
undetectable
3wg7P-5o0lA:
undetectable
3wg7C-5o0lA:
23.01
3wg7N-5o0lA:
20.26
3wg7P-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
5 / 12 LEU A  83
LEU A 107
LEU A 129
ILE A  62
VAL A  72
None
1.01A 4f4dA-5o0lA:
undetectable
4f4dA-5o0lA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
5 / 12 LEU A  83
LEU A 107
LEU A 129
ILE A  62
VAL A  72
None
1.08A 4f4dB-5o0lA:
undetectable
4f4dB-5o0lA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
5 / 12 LEU A 112
LEU A 137
LEU A 159
ILE A  96
THR A 173
None
1.22A 4f4dB-5o0lA:
undetectable
4f4dB-5o0lA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 5 THR A 125
THR A 173
LEU A 161
LEU A 137
None
1.10A 4lvcB-5o0lA:
undetectable
4lvcB-5o0lA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 7 ASP A 111
ARG A 139
SER A  90
HIS A  89
None
1.41A 4o4dA-5o0lA:
undetectable
4o4dA-5o0lA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
5 / 10 LEU A 166
ASN A 164
VAL A 121
LEU A 118
LEU A 112
None
1.21A 4po0A-5o0lA:
undetectable
4po0A-5o0lA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 ASP A 205
THR A 181
HIS A 136
LEU A 228
None
1.23A 5b1aA-5o0lA:
undetectable
5b1aC-5o0lA:
undetectable
5b1aP-5o0lA:
undetectable
5b1aA-5o0lA:
20.26
5b1aC-5o0lA:
23.01
5b1aP-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 7 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
0.87A 5b1bA-5o0lA:
undetectable
5b1bJ-5o0lA:
undetectable
5b1bA-5o0lA:
20.26
5b1bJ-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 ASP A 205
THR A 181
HIS A 136
LEU A 228
None
1.16A 5b3sA-5o0lA:
undetectable
5b3sC-5o0lA:
undetectable
5b3sP-5o0lA:
undetectable
5b3sA-5o0lA:
20.26
5b3sC-5o0lA:
23.01
5b3sP-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
5 / 12 GLU A 284
LEU A 233
SER A 283
LEU A 238
PRO A 286
None
1.37A 5hnxB-5o0lA:
undetectable
5hnxB-5o0lA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 7 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
0.97A 5iy5A-5o0lA:
undetectable
5iy5J-5o0lA:
undetectable
5iy5A-5o0lA:
20.26
5iy5J-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 7 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
0.80A 5xdqA-5o0lA:
undetectable
5xdqJ-5o0lA:
undetectable
5xdqA-5o0lA:
20.26
5xdqJ-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 LEU A 228
ASP A 205
THR A 181
HIS A 136
None
1.20A 5xdqC-5o0lA:
undetectable
5xdqN-5o0lA:
undetectable
5xdqP-5o0lA:
undetectable
5xdqC-5o0lA:
23.01
5xdqN-5o0lA:
20.26
5xdqP-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 ASP A 205
THR A 181
HIS A 136
LEU A 228
None
1.20A 5z84A-5o0lA:
undetectable
5z84C-5o0lA:
undetectable
5z84P-5o0lA:
undetectable
5z84A-5o0lA:
20.26
5z84C-5o0lA:
23.01
5z84P-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 7 LEU A 228
ASP A 205
THR A 181
HIS A 136
None
1.21A 5z84C-5o0lA:
undetectable
5z84N-5o0lA:
undetectable
5z84P-5o0lA:
undetectable
5z84C-5o0lA:
23.01
5z84N-5o0lA:
20.26
5z84P-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 ASP A 205
THR A 181
HIS A 136
LEU A 228
None
1.20A 5z85A-5o0lA:
undetectable
5z85C-5o0lA:
undetectable
5z85P-5o0lA:
undetectable
5z85A-5o0lA:
20.26
5z85C-5o0lA:
23.01
5z85P-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 7 LEU A 228
ASP A 205
THR A 181
HIS A 136
None
1.20A 5z85C-5o0lA:
undetectable
5z85N-5o0lA:
undetectable
5z85P-5o0lA:
undetectable
5z85C-5o0lA:
23.01
5z85N-5o0lA:
20.26
5z85P-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 ASP A 205
THR A 181
HIS A 136
LEU A 228
None
1.21A 5z86A-5o0lA:
undetectable
5z86C-5o0lA:
undetectable
5z86P-5o0lA:
undetectable
5z86A-5o0lA:
20.26
5z86C-5o0lA:
23.01
5z86P-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 ASP A 205
THR A 181
HIS A 136
LEU A 228
None
1.22A 5zcoA-5o0lA:
undetectable
5zcoC-5o0lA:
undetectable
5zcoP-5o0lA:
undetectable
5zcoA-5o0lA:
20.26
5zcoC-5o0lA:
23.01
5zcoP-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
0.81A 5zcoA-5o0lA:
undetectable
5zcoJ-5o0lA:
undetectable
5zcoA-5o0lA:
20.26
5zcoJ-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 LEU A 228
ASP A 205
THR A 181
HIS A 136
None
1.20A 5zcoC-5o0lA:
undetectable
5zcoN-5o0lA:
undetectable
5zcoP-5o0lA:
undetectable
5zcoC-5o0lA:
23.01
5zcoN-5o0lA:
20.26
5zcoP-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 ASP A 205
THR A 181
HIS A 136
LEU A 228
None
1.21A 5zcpA-5o0lA:
undetectable
5zcpC-5o0lA:
undetectable
5zcpP-5o0lA:
undetectable
5zcpA-5o0lA:
20.26
5zcpC-5o0lA:
23.01
5zcpP-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 ASP A 205
THR A 181
HIS A 136
LEU A 228
None
1.18A 5zcqA-5o0lA:
undetectable
5zcqC-5o0lA:
undetectable
5zcqP-5o0lA:
undetectable
5zcqA-5o0lA:
20.26
5zcqC-5o0lA:
23.01
5zcqP-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 8 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
0.82A 5zcqN-5o0lA:
undetectable
5zcqW-5o0lA:
undetectable
5zcqN-5o0lA:
20.26
5zcqW-5o0lA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
3 / 3 PRO A  56
SER A  58
SER A  59
None
0.68A 6bpyA-5o0lA:
undetectable
6bpyA-5o0lA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
5 / 10 GLY A  47
ARG A  68
ALA A  92
GLY A  66
LEU A 153
None
0.89A 6hqbA-5o0lA:
undetectable
6hqbJ-5o0lA:
undetectable
6hqbA-5o0lA:
12.38
6hqbJ-5o0lA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
5 / 10 GLY A  47
ARG A  68
ALA A  92
GLY A  66
LEU A 156
None
1.17A 6hqbA-5o0lA:
undetectable
6hqbJ-5o0lA:
undetectable
6hqbA-5o0lA:
12.38
6hqbJ-5o0lA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 7 ASP A 205
THR A 181
HIS A 136
LEU A 225
None
1.11A 6nmfA-5o0lA:
undetectable
6nmfC-5o0lA:
undetectable
6nmfP-5o0lA:
undetectable
6nmfA-5o0lA:
20.26
6nmfC-5o0lA:
23.01
6nmfP-5o0lA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5o0l RETICULON-4 RECEPTOR
(Mus
musculus)
4 / 5 LEU A 112
ARG A  61
THR A  84
LEU A 107
None
0.87A 6nmpN-5o0lA:
undetectable
6nmpW-5o0lA:
undetectable
6nmpN-5o0lA:
20.26
6nmpW-5o0lA:
10.53