SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o0w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5o0w NB474
(Vicugna
pacos) 		5 / 12 VAL E   2
ALA E  24
ARG E  76
VAL E  83
TYR E 126
 None
 0.81A 3qxvB-5o0wE:
20.4		 3qxvB-5o0wE:
64.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 4qvlV-5o0wE:
undetectable
4qvlb-5o0wE:
undetectable		 4qvlV-5o0wE:
18.97
4qvlb-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.45A 4qvlH-5o0wE:
undetectable
4qvlN-5o0wE:
undetectable		 4qvlH-5o0wE:
18.97
4qvlN-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.45A 4qvmV-5o0wE:
undetectable
4qvmb-5o0wE:
undetectable		 4qvmV-5o0wE:
18.97
4qvmb-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.45A 4qvmH-5o0wE:
undetectable
4qvmN-5o0wE:
undetectable		 4qvmH-5o0wE:
18.97
4qvmN-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.45A 4qvpV-5o0wE:
undetectable
4qvpb-5o0wE:
undetectable		 4qvpV-5o0wE:
18.97
4qvpb-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.44A 4qvpH-5o0wE:
undetectable
4qvpN-5o0wE:
undetectable		 4qvpH-5o0wE:
18.97
4qvpN-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 4qvqV-5o0wE:
undetectable
4qvqb-5o0wE:
undetectable		 4qvqV-5o0wE:
18.97
4qvqb-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 4qvqH-5o0wE:
undetectable
4qvqN-5o0wE:
undetectable		 4qvqH-5o0wE:
18.97
4qvqN-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.47A 4qvwV-5o0wE:
undetectable
4qvwb-5o0wE:
undetectable		 4qvwV-5o0wE:
18.97
4qvwb-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 4qvwH-5o0wE:
undetectable
4qvwN-5o0wE:
undetectable		 4qvwH-5o0wE:
18.97
4qvwN-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.47A 4qw0V-5o0wE:
undetectable
4qw0b-5o0wE:
undetectable		 4qw0V-5o0wE:
18.97
4qw0b-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.45A 4qw0H-5o0wE:
undetectable
4qw0N-5o0wE:
undetectable		 4qw0H-5o0wE:
18.97
4qw0N-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 4qw1V-5o0wE:
undetectable
4qw1b-5o0wE:
undetectable		 4qw1V-5o0wE:
18.97
4qw1b-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 4qw1H-5o0wE:
undetectable
4qw1N-5o0wE:
undetectable		 4qw1H-5o0wE:
18.97
4qw1N-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.47A 4qw3V-5o0wE:
undetectable
4qw3b-5o0wE:
undetectable		 4qw3V-5o0wE:
18.97
4qw3b-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 4qw3H-5o0wE:
undetectable
4qw3N-5o0wE:
undetectable		 4qw3H-5o0wE:
18.97
4qw3N-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.47A 4qwuV-5o0wE:
undetectable
4qwub-5o0wE:
undetectable		 4qwuV-5o0wE:
18.97
4qwub-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.47A 4qwuH-5o0wE:
undetectable
4qwuN-5o0wE:
undetectable		 4qwuH-5o0wE:
18.97
4qwuN-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 5bxnV-5o0wE:
undetectable
5bxnb-5o0wE:
undetectable		 5bxnV-5o0wE:
18.38
5bxnb-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 5bxnH-5o0wE:
undetectable
5bxnN-5o0wE:
undetectable		 5bxnH-5o0wE:
18.38
5bxnN-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 5cz7H-5o0wE:
undetectable
5cz7N-5o0wE:
undetectable		 5cz7H-5o0wE:
18.97
5cz7N-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 5d0xV-5o0wE:
undetectable
5d0xb-5o0wE:
undetectable		 5d0xV-5o0wE:
18.97
5d0xb-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 5d0xH-5o0wE:
undetectable
5d0xN-5o0wE:
undetectable		 5d0xH-5o0wE:
18.97
5d0xN-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 5l66V-5o0wE:
undetectable
5l66b-5o0wE:
undetectable		 5l66V-5o0wE:
18.97
5l66b-5o0wE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5o0w NB474
(Vicugna
pacos) 		5 / 11 THR E 104
THR E 123
ARG E  76
GLY E  35
ALA E  33
 None
 1.46A 5l66H-5o0wE:
undetectable
5l66N-5o0wE:
undetectable		 5l66H-5o0wE:
18.97
5l66N-5o0wE:
19.43