SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o0x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 5o0x PUTATIVE FERRIC
REDUCTASE
(Cylindrospermum
stagnale) 		4 / 4 LEU A 533
PRO A 467
ILE A 550
LEU A 547
 None
 0.93A 1ya4B-5o0xA:
undetectable		 1ya4B-5o0xA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 5o0x PUTATIVE FERRIC
REDUCTASE
(Cylindrospermum
stagnale) 		4 / 4 LEU A 533
PRO A 467
ILE A 550
LEU A 547
 None
 1.03A 1ya4C-5o0xA:
undetectable		 1ya4C-5o0xA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 5o0x PUTATIVE FERRIC
REDUCTASE
(Cylindrospermum
stagnale) 		5 / 12 LEU A 596
LEU A 563
ILE A 550
ILE A 546
LEU A 533
 None
 1.06A 2bdmA-5o0xA:
undetectable		 2bdmA-5o0xA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 5o0x PUTATIVE FERRIC
REDUCTASE
(Cylindrospermum
stagnale) 		4 / 7 PHE A 578
TRP A 580
SER A 425
ARG A 478
 None
None
P6G  A 812 ( 3.6A)
CL  A 802 (-3.5A)
 1.37A 2v7uB-5o0xA:
4.5		 2v7uB-5o0xA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5o0x PUTATIVE FERRIC
REDUCTASE
(Cylindrospermum
stagnale) 		4 / 7 ILE A 477
GLY A 485
VAL A 510
LEU A 422
 None
CL  A 803 ( 4.4A)
None
None
 0.91A 3elzA-5o0xA:
undetectable		 3elzA-5o0xA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 5o0x PUTATIVE FERRIC
REDUCTASE
(Cylindrospermum
stagnale) 		3 / 3 LYS A 548
ARG A 434
VAL A 472
 PEG  A 816 (-2.5A)
CL  A 804 ( 4.1A)
None
 0.87A 4x3uA-5o0xA:
1.2
4x3uB-5o0xA:
1.5		 4x3uA-5o0xA:
12.03
4x3uB-5o0xA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 5o0x PUTATIVE FERRIC
REDUCTASE
(Cylindrospermum
stagnale) 		4 / 8 ASN A 439
PHE A 438
THR A 523
GLY A 443
 PEG  A 821 (-4.9A)
None
None
None
 0.63A 5nzxA-5o0xA:
undetectable		 5nzxA-5o0xA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 5o0x PUTATIVE FERRIC
REDUCTASE
(Cylindrospermum
stagnale) 		4 / 7 ASN A 439
PHE A 438
THR A 523
GLY A 443
 PEG  A 821 (-4.9A)
None
None
None
 0.69A 5nzyA-5o0xA:
2.9		 5nzyA-5o0xA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5o0x PUTATIVE FERRIC
REDUCTASE
(Cylindrospermum
stagnale) 		4 / 6 TYR A 684
ASP A 646
GLN A 676
GLU A 649
 GOL  A 826 ( 4.6A)
None
None
None
 1.18A 6djzB-5o0xA:
undetectable		 6djzB-5o0xA:
21.97