SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o19'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5o19 GENOME POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 6 ASP A 276
LEU A 275
VAL A 274
ILE A 273
 None
 1.01A 1s9qA-5o19A:
undetectable		 1s9qA-5o19A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 5o19 GENOME POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 8 LEU A 321
LEU A 275
ASP A 276
ASP A 278
 None
 1.05A 2j2pA-5o19A:
undetectable
2j2pB-5o19A:
undetectable		 2j2pA-5o19A:
15.21
2j2pB-5o19A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 5o19 GENOME POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 6 ILE A 273
PRO A 250
LEU A 212
ILE A 202
 None
 0.90A 2q83B-5o19A:
undetectable		 2q83B-5o19A:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 5o19 GENOME POLYPROTEIN
(Japanese
encephalitis
virus) 		3 / 3 THR A 230
PRO A 226
THR A 228
 None
 0.90A 316dC-5o19A:
undetectable		 316dC-5o19A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5o19 GENOME POLYPROTEIN
(Japanese
encephalitis
virus) 		4 / 7 ILE A 308
THR A 302
VAL A 285
ASP A 278
 None
SO4  A 401 (-3.3A)
None
None
 1.28A 4iarA-5o19A:
undetectable		 4iarA-5o19A:
12.47