SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o1r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 5o1r GNA2132
(Neisseria
meningitidis) 		5 / 12 VAL A 401
GLY A 422
ASN A 320
VAL A 344
PHE A 393
 None
 1.45A 1a27A-5o1rA:
undetectable		 1a27A-5o1rA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5o1r GNA2132
(Neisseria
meningitidis) 		3 / 3 TRP A 381
HIS A 325
MET A 363
 None
 1.44A 1l5qB-5o1rA:
undetectable		 1l5qB-5o1rA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 5o1r GNA2132
(Neisseria
meningitidis) 		4 / 6 VAL A 401
PHE A 340
VAL A 318
PHE A 368
 None
 1.09A 3soaA-5o1rA:
undetectable		 3soaA-5o1rA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 5o1r GNA2132
(Neisseria
meningitidis) 		5 / 12 ASP A 356
GLY A 338
HIS A 325
GLY A 418
TYR A 405
 None
 1.08A 4lxzC-5o1rA:
undetectable		 4lxzC-5o1rA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 5o1r GNA2132
(Neisseria
meningitidis) 		5 / 12 ALA A 341
TYR A 319
VAL A 318
PHE A 420
GLY A 321
 None
 1.22A 4mm4B-5o1rA:
undetectable		 4mm4B-5o1rA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 5o1r GNA2132
(Neisseria
meningitidis) 		5 / 9 ALA A 341
TYR A 319
GLY A 403
PHE A 420
GLY A 321
 None
 1.30A 4mmeA-5o1rA:
undetectable		 4mmeA-5o1rA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 5o1r GNA2132
(Neisseria
meningitidis) 		5 / 9 ALA A 341
TYR A 319
GLY A 403
PHE A 420
GLY A 321
 None
 1.28A 4mmfA-5o1rA:
undetectable		 4mmfA-5o1rA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 5o1r GNA2132
(Neisseria
meningitidis) 		3 / 3 HIS A 327
ASP A 359
HIS A 362
 None
 0.75A 5n1tW-5o1rA:
undetectable		 5n1tW-5o1rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 5o1r GNA2132
(Neisseria
meningitidis) 		3 / 3 LYS A 414
HIS A 362
HIS A 327
 None
 1.21A 5oexA-5o1rA:
undetectable		 5oexA-5o1rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 5o1r GNA2132
(Neisseria
meningitidis) 		3 / 3 LYS A 414
HIS A 362
HIS A 327
 None
 1.25A 5oexB-5o1rA:
undetectable		 5oexB-5o1rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 5o1r GNA2132
(Neisseria
meningitidis) 		3 / 3 LYS A 414
HIS A 362
HIS A 327
 None
 1.26A 5oexC-5o1rA:
undetectable		 5oexC-5o1rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 5o1r GNA2132
(Neisseria
meningitidis) 		3 / 3 LYS A 414
HIS A 362
HIS A 327
 None
 1.20A 5oexD-5o1rA:
2.0		 5oexD-5o1rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 5o1r GNA2132
(Neisseria
meningitidis) 		3 / 3 TYR A 334
HIS A 362
MET A 363
 None
 1.11A 6af6A-5o1rA:
undetectable		 6af6A-5o1rA:
undetectable