SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o1t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 5o1t PROTEIN NRD1
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 359
PHE A 362
ALA A 363
LEU A 341
 None
 0.97A 1ukbA-5o1tA:
undetectable		 1ukbA-5o1tA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 5o1t PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 341
VAL A 346
GLY A 345
ALA A 377
LEU A 355
 None
 1.06A 2bxgA-5o1tA:
undetectable		 2bxgA-5o1tA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 5o1t PROTEIN NRD1
(Saccharomyces
cerevisiae) 		3 / 3 THR A 431
ASP A 432
ALA A 433
 None
 0.08A 5g5gB-5o1tA:
undetectable		 5g5gB-5o1tA:
18.61