SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o1w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 5o1w PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 462
ARG A 413
PHE A 410
ILE A 334
LEU A 430
 None
 1.00A 1drfA-5o1wA:
undetectable		 1drfA-5o1wA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 5o1w PROTEIN NRD1
(Saccharomyces
cerevisiae) 		4 / 5 ASP A 461
GLU A 459
GLY A 444
GLN A 442
 None
 1.50A 3w9tE-5o1wA:
undetectable		 3w9tE-5o1wA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 5o1w PROTEIN NRD1
(Saccharomyces
cerevisiae) 		5 / 12 SER A 469
ILE A 425
PRO A 426
ILE A 334
SER A 438
 None
 1.35A 4uroB-5o1wA:
undetectable		 4uroB-5o1wA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 5o1w PROTEIN NRD1
(Saccharomyces
cerevisiae) 		3 / 3 THR A 431
ASP A 432
ALA A 433
 None
 0.00A 5g5gB-5o1wA:
undetectable		 5g5gB-5o1wA:
23.49