SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o27'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_P_TFPP201_1 (PROTEIN S100-A4)	5o27	NEUROGLOBIN (Mus musculus)	4 / 7	GLY A 110 GLY A 138 MET A 69 PHE A 28	None	0.97A	3ko0M-5o27A: undetectable 3ko0P-5o27A: undetectable	3ko0M-5o27A: 18.37 3ko0P-5o27A: 18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TBG_A_RTZA1_1 (CYTOCHROME P450 2D6)	5o27	NEUROGLOBIN (Mus musculus)	5 / 12	LEU A 38 PHE A 42 GLY A 110 LEU A 113 PHE A 106	HEM A 201 ( 4.7A) HEM A 201 (-3.8A) None XE A 206 ( 4.5A) XE A 211 (-4.3A)	1.19A	3tbgA-5o27A: undetectable	3tbgA-5o27A: 14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TBG_C_RTZC1_1 (CYTOCHROME P450 2D6)	5o27	NEUROGLOBIN (Mus musculus)	5 / 12	LEU A 38 PHE A 42 GLY A 110 LEU A 113 PHE A 106	HEM A 201 ( 4.7A) HEM A 201 (-3.8A) None XE A 206 ( 4.5A) XE A 211 (-4.3A)	1.21A	3tbgC-5o27A: undetectable	3tbgC-5o27A: 14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FOS_B_PQNB2002_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2)	5o27	NEUROGLOBIN (Mus musculus)	4 / 6	MET A 144 TRP A 140 ALA A 75 LEU A 85	None XE A 205 (-4.4A) XE A 205 ( 4.5A) None	1.15A	6fosB-5o27A: undetectable	6fosB-5o27A: 16.89

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KO0_P_TFPP201_1","PROTEIN S100-A4;PROTEIN S100-A4","5o27","NEUROGLOBIN","Mus musculus",4,"GLY A 110;GLY A 138;MET A  69;PHE A  28","None","0.97A","3ko0M-5o27A:undetectable;3ko0P-5o27A:undetectable","3ko0M-5o27A:18.37;3ko0P-5o27A:18.37"],["3TBG_A_RTZA1_1","CYTOCHROME P450 2D6","5o27","NEUROGLOBIN","Mus musculus",5,"LEU A  38;PHE A  42;GLY A 110;LEU A 113;PHE A 106","HEM A 201 ( 4.7A);HEM A 201 (-3.8A);None; XE A 206 ( 4.5A); XE A 211 (-4.3A)","1.19A","3tbgA-5o27A:undetectable","3tbgA-5o27A:14.82"],["3TBG_C_RTZC1_1","CYTOCHROME P450 2D6","5o27","NEUROGLOBIN","Mus musculus",5,"LEU A  38;PHE A  42;GLY A 110;LEU A 113;PHE A 106","HEM A 201 ( 4.7A);HEM A 201 (-3.8A);None; XE A 206 ( 4.5A); XE A 211 (-4.3A)","1.21A","3tbgC-5o27A:undetectable","3tbgC-5o27A:14.82"],["6FOS_B_PQNB2002_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A2","5o27","NEUROGLOBIN","Mus musculus",4,"MET A 144;TRP A 140;ALA A  75;LEU A  85","None; XE A 205 (-4.4A); XE A 205 ( 4.5A);None","1.15A","6fosB-5o27A:undetectable","6fosB-5o27A:16.89"]]