SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o2j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_B_STIB4_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB
(Pseudomonas
stutzeri) 		4 / 6 LEU A 215
VAL A  45
ILE A  61
ARG A  25
 None
 1.09A 1opjB-5o2jA:
undetectable		 1opjB-5o2jA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_SAMB293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB
(Pseudomonas
stutzeri) 		5 / 12 TYR A  94
ALA A 159
ASP A 156
ILE A 251
TYR A  49
 2PO  A 301 (-4.9A)
None
None
None
2PO  A 301 (-4.7A)
 1.44A 1xvaB-5o2jA:
undetectable		 1xvaB-5o2jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB
(Pseudomonas
stutzeri) 		5 / 11 ASP A  48
LEU A  14
ASP A 121
ILE A  53
SER A  50
 None
 1.40A 3o94A-5o2jA:
undetectable		 3o94A-5o2jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB
(Pseudomonas
stutzeri) 		5 / 11 ASP A  48
LEU A  14
ASP A 121
ILE A  53
SER A  50
 None
 1.39A 3o94B-5o2jA:
undetectable		 3o94B-5o2jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB
(Pseudomonas
stutzeri) 		5 / 11 ASP A  48
LEU A  14
ASP A 121
ILE A  53
SER A  50
 None
 1.39A 3o94C-5o2jA:
undetectable		 3o94C-5o2jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB
(Pseudomonas
stutzeri) 		5 / 11 ASP A  48
LEU A  14
ASP A 121
ILE A  53
SER A  50
 None
 1.39A 3o94D-5o2jA:
undetectable		 3o94D-5o2jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB
(Pseudomonas
stutzeri) 		4 / 6 GLU A 214
ASP A   3
ASN A 210
ARG A 208
 None
 1.10A 4ntxA-5o2jA:
undetectable
4ntxC-5o2jA:
undetectable		 4ntxA-5o2jA:
13.38
4ntxC-5o2jA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB
(Pseudomonas
stutzeri) 		5 / 12 ALA A 169
GLY A 114
GLN A 149
GLY A 143
LEU A 135
 None
 1.04A 4uilH-5o2jA:
undetectable
4uilL-5o2jA:
undetectable		 4uilH-5o2jA:
undetectable
4uilL-5o2jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB
(Pseudomonas
stutzeri) 		3 / 3 GLU A  54
ALA A  55
PHE A  58
 None
 0.13A 4v1fA-5o2jA:
undetectable		 4v1fA-5o2jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB
(Pseudomonas
stutzeri) 		3 / 3 GLU A  54
ALA A  55
PHE A  58
 None
 0.11A 4v1fC-5o2jA:
undetectable		 4v1fC-5o2jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB
(Pseudomonas
stutzeri) 		4 / 7 GLY A 153
PHE A 151
SER A 127
ASP A 121
 None
None
2PO  A 301 ( 4.7A)
None
 1.11A 5n5dB-5o2jA:
2.6		 5n5dB-5o2jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB
(Pseudomonas
stutzeri) 		4 / 8 PHE A 177
LEU A 172
ILE A 186
VAL A 191
 None
 0.83A 5nujA-5o2jA:
undetectable		 5nujA-5o2jA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB
(Pseudomonas
stutzeri) 		4 / 5 TYR A  94
GLN A 202
GLY A 255
ILE A 130
 2PO  A 301 (-4.9A)
None
None
None
 1.31A 6debB-5o2jA:
undetectable		 6debB-5o2jA:
20.00