SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		4 / 4 ARG A  25
ALA A  24
ALA A  15
GLU A  50
 None
 1.10A 1e7bA-5o30A:
undetectable		 1e7bA-5o30A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		4 / 5 ARG A  25
ALA A  24
ALA A  15
GLU A  50
 None
 1.14A 1e7cA-5o30A:
undetectable		 1e7cA-5o30A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		3 / 3 MET A 231
LEU A 234
SER A 235
 None
 0.38A 1ee2A-5o30A:
undetectable		 1ee2A-5o30A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		4 / 7 LEU A 136
VAL A 188
GLY A 145
GLY A 143
 None
 0.71A 2wd9A-5o30A:
2.9		 2wd9A-5o30A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		4 / 8 LEU A 136
VAL A 188
GLY A 145
GLY A 143
 None
 0.70A 2wd9B-5o30A:
3.1		 2wd9B-5o30A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		5 / 8 GLY A 155
ASN A 173
VAL A 179
SER A 152
THR A 101
 None
 1.09A 2yoeB-5o30A:
undetectable
2yoeC-5o30A:
undetectable		 2yoeB-5o30A:
19.62
2yoeC-5o30A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		5 / 12 PHE A 256
ALA A 239
ILE A  12
ALA A  15
GLU A  49
 None
 1.07A 3nxuA-5o30A:
undetectable		 3nxuA-5o30A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		5 / 12 LEU A 132
GLY A 131
ASN A  80
ILE A 175
ALA A 172
 None
 1.07A 3uwlD-5o30A:
undetectable		 3uwlD-5o30A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		4 / 8 GLY A 194
THR A 195
THR A 154
ARG A 169
 None
 0.92A 4k87A-5o30A:
3.1		 4k87A-5o30A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		4 / 5 VAL A 148
LEU A  23
VAL A  19
PHE A 150
 None
 1.03A 4lb0B-5o30A:
undetectable		 4lb0B-5o30A:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		5 / 9 ALA A 172
ILE A 104
VAL A 105
GLY A 166
VAL A 120
 None
 1.13A 4r20B-5o30A:
undetectable		 4r20B-5o30A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		4 / 4 LEU A  11
ILE A  69
HIS A  37
VAL A  35
 None
 1.24A 4xyzA-5o30A:
undetectable		 4xyzA-5o30A:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA203_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		5 / 9 TYR A 165
GLY A 166
GLY A 167
VAL A 120
ASN A 124
 None
 1.23A 5f8yA-5o30A:
undetectable		 5f8yA-5o30A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		5 / 9 TYR A 165
GLY A 166
GLY A 167
VAL A 120
ASN A 124
 None
 1.23A 5f8yB-5o30A:
undetectable		 5f8yB-5o30A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		5 / 12 GLY A 261
ASP A 159
GLY A 166
SER A 152
PHE A 253
 None
 1.10A 5vooA-5o30A:
3.1		 5vooA-5o30A:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		5 / 12 GLY A 261
ASP A 159
GLY A 166
SER A 152
PHE A 253
 None
 1.08A 5vooB-5o30A:
undetectable		 5vooB-5o30A:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		5 / 12 GLY A 261
ASP A 159
GLY A 166
SER A 152
PHE A 253
 None
 1.10A 5vooC-5o30A:
undetectable		 5vooC-5o30A:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		4 / 6 PHE A 253
GLY A 194
THR A 151
TYR A 165
 None
 1.13A 6ag0A-5o30A:
undetectable		 6ag0A-5o30A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		4 / 6 PHE A 253
GLY A 194
THR A 151
TYR A 165
 None
 1.14A 6ag0C-5o30A:
undetectable		 6ag0C-5o30A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		4 / 7 ILE A 219
GLN A 222
VAL A 223
TRP A 260
 None
 0.80A 6cduC-5o30A:
undetectable
6cduD-5o30A:
undetectable		 6cduC-5o30A:
21.94
6cduD-5o30A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		4 / 8 ILE A 219
GLN A 222
TRP A 260
THR A 195
 None
 0.96A 6cduG-5o30A:
undetectable
6cduH-5o30A:
undetectable		 6cduG-5o30A:
21.94
6cduH-5o30A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		4 / 8 ILE A 219
GLN A 222
VAL A 223
TRP A 260
 None
 0.57A 6cduG-5o30A:
undetectable
6cduH-5o30A:
undetectable		 6cduG-5o30A:
21.94
6cduH-5o30A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 5o30 PUTATIVE
OXIDOREDUCTASE
(Ilumatobacter
coccineus) 		4 / 4 VAL A  48
GLY A  41
ASP A  42
ASP A  53
 None
 1.12A 6cjkC-5o30A:
undetectable		 6cjkC-5o30A:
20.69