SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o34'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1U18_A_HSMA401_1 (NITROPHORIN 1)	5o34	ENOYL-COA HYDRATASE CARB HOMOLOGUE (Streptomyces cattleya)	4 / 4	ASP A 217 LEU A 220 LEU A 215 LEU A 219	None	1.27A	1u18A-5o34A: undetectable	1u18A-5o34A: 17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OPX_A_DXCA1002_0 (ALDEHYDE DEHYDROGENASE A)	5o34	ENOYL-COA HYDRATASE CARB HOMOLOGUE (Streptomyces cattleya)	3 / 3	GLY A 98 ARG A 101 TYR A 96	None	0.74A	2opxA-5o34A: undetectable	2opxA-5o34A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K37_A_BCZA468_1 (NEURAMINIDASE)	5o34	ENOYL-COA HYDRATASE CARB HOMOLOGUE (Streptomyces cattleya)	3 / 3	ASP A 127 ARG A 71 ARG A 82	None	1.05A	3k37A-5o34A: undetectable	3k37A-5o34A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7X_B_SASB804_2 (SEPIAPTERIN REDUCTASE)	5o34	ENOYL-COA HYDRATASE CARB HOMOLOGUE (Streptomyces cattleya)	3 / 3	LEU A 159 MET A 189 ASP A 207	None	0.81A	4j7xB-5o34A: undetectable	4j7xB-5o34A: 14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FSA_A_X2NA590_1 (CYP51 VARIANT1)	5o34	ENOYL-COA HYDRATASE CARB HOMOLOGUE (Streptomyces cattleya)	5 / 12	ALA A 86 LEU A 95 ILE A 146 PHE A 60 GLY A 154	None	1.14A	5fsaA-5o34A: undetectable	5fsaA-5o34A: 11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XOO_B_ADNB503_1 (GLYCOSAMINOGLYCAN XYLOSYLKINASE)	5o34	ENOYL-COA HYDRATASE CARB HOMOLOGUE (Streptomyces cattleya)	4 / 5	LEU A 229 VAL A 224 GLU A 222 LEU A 165	None	0.85A	5xooB-5o34A: undetectable	5xooB-5o34A: 24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YW0_A_ACTA410_0 (UNCHARACTERIZED PROTEIN KDOO)	5o34	ENOYL-COA HYDRATASE CARB HOMOLOGUE (Streptomyces cattleya)	4 / 4	GLY A 166 LEU A 165 VAL A 224 GLU A 222	None	1.22A	5yw0A-5o34A: undetectable	5yw0A-5o34A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EF6_A_ACTA405_0 (AMINOGLYCOSIDE PHOSPHOTRANSFERASE)	5o34	ENOYL-COA HYDRATASE CARB HOMOLOGUE (Streptomyces cattleya)	4 / 6	PRO A 141 GLN A 249 ARG A 252 ILE A 138	None	1.38A	6ef6A-5o34A: undetectable	6ef6A-5o34A: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1U18_A_HSMA401_1","NITROPHORIN 1","5o34","ENOYL-COA HYDRATASE CARB HOMOLOGUE","Streptomyces cattleya",4,"ASP A 217;LEU A 220;LEU A 215;LEU A 219","None","1.27A","1u18A-5o34A:undetectable","1u18A-5o34A:17.58"],["2OPX_A_DXCA1002_0","ALDEHYDE DEHYDROGENASE A","5o34","ENOYL-COA HYDRATASE CARB HOMOLOGUE","Streptomyces cattleya",3,"GLY A  98;ARG A 101;TYR A  96","None","0.74A","2opxA-5o34A:undetectable","2opxA-5o34A:undetectable"],["3K37_A_BCZA468_1","NEURAMINIDASE","5o34","ENOYL-COA HYDRATASE CARB HOMOLOGUE","Streptomyces cattleya",3,"ASP A 127;ARG A  71;ARG A  82","None","1.05A","3k37A-5o34A:undetectable","3k37A-5o34A:undetectable"],["4J7X_B_SASB804_2","SEPIAPTERIN REDUCTASE","5o34","ENOYL-COA HYDRATASE CARB HOMOLOGUE","Streptomyces cattleya",3,"LEU A 159;MET A 189;ASP A 207","None","0.81A","4j7xB-5o34A:undetectable","4j7xB-5o34A:14.89"],["5FSA_A_X2NA590_1","CYP51 VARIANT1","5o34","ENOYL-COA HYDRATASE CARB HOMOLOGUE","Streptomyces cattleya",5,"ALA A  86;LEU A  95;ILE A 146;PHE A  60;GLY A 154","None","1.14A","5fsaA-5o34A:undetectable","5fsaA-5o34A:11.54"],["5XOO_B_ADNB503_1","GLYCOSAMINOGLYCAN XYLOSYLKINASE","5o34","ENOYL-COA HYDRATASE CARB HOMOLOGUE","Streptomyces cattleya",4,"LEU A 229;VAL A 224;GLU A 222;LEU A 165","None","0.85A","5xooB-5o34A:undetectable","5xooB-5o34A:24.72"],["5YW0_A_ACTA410_0","UNCHARACTERIZED PROTEIN KDOO","5o34","ENOYL-COA HYDRATASE CARB HOMOLOGUE","Streptomyces cattleya",4,"GLY A 166;LEU A 165;VAL A 224;GLU A 222","None","1.22A","5yw0A-5o34A:undetectable","5yw0A-5o34A:undetectable"],["6EF6_A_ACTA405_0","AMINOGLYCOSIDE PHOSPHOTRANSFERASE","5o34","ENOYL-COA HYDRATASE CARB HOMOLOGUE","Streptomyces cattleya",4,"PRO A 141;GLN A 249;ARG A 252;ILE A 138","None","1.38A","6ef6A-5o34A:undetectable","6ef6A-5o34A:undetectable"]]