SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o3z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 GLY A   9
GLY A  10
GLY A  11
LEU A  34
ASP A  61
 None
 1.01A 1qzzA-5o3zA:
6.9		 1qzzA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 GLY A   9
GLY A  10
GLY A  11
LEU A  34
ASP A  61
 None
 0.98A 1xdsA-5o3zA:
7.3		 1xdsA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 GLY A   9
GLY A  10
GLY A  11
LEU A  34
ASP A  61
 None
 0.91A 1xdsB-5o3zA:
7.0		 1xdsB-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 10 SER A 108
ALA A 157
ALA A 156
SER A 155
TYR A 154
 None
 1.43A 2r2vC-5o3zA:
undetectable
2r2vF-5o3zA:
undetectable
2r2vG-5o3zA:
undetectable		 2r2vC-5o3zA:
undetectable
2r2vF-5o3zA:
undetectable
2r2vG-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_A_TMQA611_1
(DHFR-TS)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 11 ALA A  62
ILE A   8
ILE A 136
LEU A 168
THR A  63
 None
 1.07A 3clbA-5o3zA:
undetectable		 3clbA-5o3zA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_2
(HIV-1 PROTEASE)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 10 ASP A  33
VAL A  60
ILE A   8
GLY A 115
VAL A 114
 None
 1.03A 3oxvB-5o3zA:
undetectable		 3oxvB-5o3zA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 GLY A   9
ASP A  33
LEU A  34
ASN A  35
ASP A  61
 None
 0.70A 3q87B-5o3zA:
7.3		 3q87B-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 ASP A  83
ILE A 132
ASP A 130
ARG A 129
ASP A  76
 None
 1.31A 3topA-5o3zA:
undetectable		 3topA-5o3zA:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		4 / 5 GLY A   9
THR A  63
VAL A  60
ASP A  33
 None
 1.00A 4eohA-5o3zA:
5.3		 4eohA-5o3zA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 GLY A   9
GLY A  10
GLY A  11
LEU A  34
ALA A  62
 None
 0.77A 4htfA-5o3zA:
2.3		 4htfA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 GLY A   9
GLY A  11
LEU A  34
ASP A  61
ALA A  62
 None
 0.87A 4krhA-5o3zA:
2.9		 4krhA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 11 GLY A   9
GLY A  10
ASP A  33
LEU A  34
ASP A  61
 None
 0.76A 4pghA-5o3zA:
7.0		 4pghA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 GLY A   9
GLY A  11
LEU A  34
ALA A  62
THR A  63
 None
 0.69A 4uckA-5o3zA:
5.5		 4uckA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 GLY A   9
LEU A  34
ALA A  62
THR A  63
ALA A  89
 None
 0.92A 4uckA-5o3zA:
5.5		 4uckA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 GLY A  10
LEU A  34
ALA A  62
THR A  63
ALA A  89
 None
 0.89A 4uckA-5o3zA:
5.5		 4uckA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 GLY A  10
LEU A  34
ALA A  62
THR A  63
ALA A  89
 None
 0.87A 4uckB-5o3zA:
undetectable		 4uckB-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 VAL A 146
TYR A 154
ILE A  97
GLN A  99
HIS A 150
 None
 1.44A 4xucA-5o3zA:
8.1		 4xucA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 VAL A 146
TYR A 154
ILE A  97
GLN A  99
HIS A 150
 None
 1.41A 4xudA-5o3zA:
7.5		 4xudA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 VAL A 146
TYR A 154
ILE A  97
GLN A  99
HIS A 150
 None
 1.41A 4xueA-5o3zA:
8.1		 4xueA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 GLY A 115
GLN A 110
ILE A   8
VAL A  68
VAL A  60
 None
 1.00A 5dpdA-5o3zA:
3.2		 5dpdA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 TYR A 227
GLY A   9
ASP A  33
LEU A  34
VAL A 111
 None
 1.09A 5dpdB-5o3zA:
2.0		 5dpdB-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 12 ALA A  25
GLY A  21
GLU A  20
TYR A 227
PHE A  17
 None
 1.49A 5vlmF-5o3zA:
undetectable		 5vlmF-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 10 GLY A 115
VAL A   6
VAL A  60
ALA A  32
LEU A  85
 None
 0.99A 6czmA-5o3zA:
undetectable
6czmC-5o3zA:
undetectable		 6czmA-5o3zA:
undetectable
6czmC-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		4 / 6 ILE A 136
TYR A 116
LEU A 164
VAL A 179
 None
 1.16A 6f6jA-5o3zA:
undetectable		 6f6jA-5o3zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I5Z_D_SAMD401_0
(O-METHYLTRANSFERASE
1)		 5o3z SORBITOL-6-PHOSPHATE
DEHYDROGENASE
(Erwinia
amylovora) 		5 / 11 GLY A   9
GLY A  11
ASP A  33
LEU A  34
ASP A  61
 None
 0.86A 6i5zD-5o3zA:
6.8		 6i5zD-5o3zA:
undetectable