SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o4u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 5o4u FLAGELLIN
(Pyrococcus
furiosus) 		5 / 12 GLY A 166
GLY A 168
VAL A 171
ASN A  98
TYR A  70
 None
 1.24A 4f84A-5o4uA:
undetectable		 4f84A-5o4uA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5o4u FLAGELLIN
(Pyrococcus
furiosus) 		5 / 12 ILE A 176
LEU A  96
PHE A 172
GLY A 173
GLY A 175
 None
 1.18A 5l6eA-5o4uA:
undetectable		 5l6eA-5o4uA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5o4u FLAGELLIN
(Pyrococcus
furiosus) 		5 / 12 VAL A  71
LEU A 105
LEU A  96
THR A 132
GLY A 168
 None
 1.17A 6b0lB-5o4uA:
undetectable		 6b0lB-5o4uA:
19.34