SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o5a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 7 PHE A 675
GLY A 726
ILE A 700
VAL A 701
 None
 0.65A 1p2yA-5o5aA:
undetectable		 1p2yA-5o5aA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 5o5a PEREGRIN
(Homo
sapiens) 		3 / 3 LEU A 637
LEU A 630
MET A 739
 None
 0.75A 1ya3B-5o5aA:
undetectable		 1ya3B-5o5aA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 5 TYR A 687
ARG A 686
MET A 678
THR A 677
 None
 1.14A 2eimJ-5o5aA:
undetectable		 2eimJ-5o5aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 5 TYR A 687
ARG A 686
MET A 678
THR A 677
 None
 1.10A 2eimW-5o5aA:
undetectable		 2eimW-5o5aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 7 TYR A 687
ARG A 686
MET A 678
THR A 677
 None
 1.14A 2zxwN-5o5aA:
undetectable
2zxwW-5o5aA:
undetectable		 2zxwN-5o5aA:
undetectable
2zxwW-5o5aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 5 TYR A 687
ARG A 686
MET A 678
THR A 677
 None
 1.06A 3abkN-5o5aA:
undetectable
3abkW-5o5aA:
undetectable		 3abkN-5o5aA:
undetectable
3abkW-5o5aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 5 TYR A 687
ARG A 686
MET A 678
THR A 677
 None
 1.31A 3ag1J-5o5aA:
undetectable		 3ag1J-5o5aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 5 TYR A 687
ARG A 686
MET A 678
THR A 677
 None
 1.05A 3ag2J-5o5aA:
undetectable		 3ag2J-5o5aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 5 TYR A 687
ARG A 686
MET A 678
THR A 677
 None
 1.17A 3ag4J-5o5aA:
undetectable		 3ag4J-5o5aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 5 PHE A 675
GLY A 725
ILE A 700
VAL A 701
 None
 0.88A 3wrkA-5o5aA:
undetectable		 3wrkA-5o5aA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 6 VAL A 657
VAL A 662
TYR A 665
ASN A 708
 9LN  A 802 ( 4.1A)
None
None
9LN  A 802 (-3.2A)
 0.37A 5pbeA-5o5aA:
16.0		 5pbeA-5o5aA:
30.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W8A_A_SAMA300_0
(AUTOINDUCER SYNTHASE)		 5o5a PEREGRIN
(Homo
sapiens) 		5 / 12 LEU A 729
TYR A 687
MET A 678
PHE A 675
ILE A 700
 None
 1.43A 5w8aA-5o5aA:
undetectable		 5w8aA-5o5aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 5 TYR A 687
ARG A 686
MET A 678
THR A 677
 None
 1.36A 5w97J-5o5aA:
undetectable		 5w97J-5o5aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 5 TYR A 687
ARG A 686
MET A 678
THR A 677
 None
 1.28A 5wauJ-5o5aA:
undetectable		 5wauJ-5o5aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 5 TYR A 687
ARG A 686
MET A 678
THR A 677
 None
 1.23A 5x1bW-5o5aA:
undetectable		 5x1bW-5o5aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 6 TYR A 687
LEU A 644
GLU A 694
LEU A 729
 None
 1.18A 5xooA-5o5aA:
undetectable		 5xooA-5o5aA:
23.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 8 VAL A 657
CYH A 704
TYR A 707
ASN A 708
 9LN  A 802 ( 4.1A)
9LN  A 802 (-3.4A)
9LN  A 802 ( 4.7A)
9LN  A 802 (-3.2A)
 0.29A 5y1yA-5o5aA:
13.9		 5y1yA-5o5aA:
31.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5o5a PEREGRIN
(Homo
sapiens) 		4 / 5 TYR A 687
ARG A 686
MET A 678
THR A 677
 None
 1.28A 6nknJ-5o5aA:
undetectable		 6nknJ-5o5aA:
undetectable