SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o5d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_1
(EXOGLUCANASE 1)
5o5d GLUCANASE
(Trichoderma
atroviride)
12 / 12 ALA A 143
TYR A 145
TYR A 171
ASP A 173
SER A 174
GLN A 175
GLU A 212
ASP A 214
GLU A 217
THR A 246
ARG A 251
ASP A 369
BTB  A 604 (-3.5A)
BTB  A 604 (-3.8A)
None
BTB  A 604 (-3.7A)
BTB  A 604 (-3.4A)
BTB  A 604 (-3.8A)
BTB  A 604 (-2.7A)
BTB  A 604 ( 3.4A)
BTB  A 604 ( 3.0A)
None
None
None
0.52A 1dy4A-5o5dA:
68.9
1dy4A-5o5dA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_2
(EXOGLUCANASE 1)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 5 HIS A 228
TRP A 367
ALA A 372
TRP A 376
GOL  A 608 (-4.0A)
GOL  A 607 ( 3.5A)
None
BTB  A 604 (-4.9A)
0.35A 1dy4A-5o5dA:
68.9
1dy4A-5o5dA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_F_CCSF47_0
(GLUTATHIONE
S-TRANSFERASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 5 THR A   5
LEU A  73
GLY A  75
TYR A 167
None
PCA  A   1 ( 4.6A)
None
None
1.30A 1gtiF-5o5dA:
undetectable
1gtiF-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)
5o5d GLUCANASE
(Trichoderma
atroviride)
5 / 10 PRO A 382
THR A 389
PRO A 390
GLY A 391
GLY A 339
None
None
GOL  A 609 ( 4.8A)
GOL  A 609 (-4.0A)
None
0.92A 1h4oA-5o5dA:
undetectable
1h4oB-5o5dA:
undetectable
1h4oA-5o5dA:
undetectable
1h4oB-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 8 PRO A 382
THR A 389
PRO A 390
GLY A 391
None
None
GOL  A 609 ( 4.8A)
GOL  A 609 (-4.0A)
0.84A 1h4oB-5o5dA:
undetectable
1h4oB-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 8 PRO A 382
THR A 389
PRO A 390
GLY A 391
None
None
GOL  A 609 ( 4.8A)
GOL  A 609 (-4.0A)
0.83A 1h4oG-5o5dA:
undetectable
1h4oG-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 8 PRO A 382
THR A 389
PRO A 390
GLY A 391
None
None
GOL  A 609 ( 4.8A)
GOL  A 609 (-4.0A)
0.86A 1oc3A-5o5dA:
undetectable
1oc3A-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
3 / 3 GLU A 217
ASN A 141
TRP A 376
BTB  A 604 ( 3.0A)
BTB  A 604 (-3.7A)
BTB  A 604 (-4.9A)
1.28A 1r15D-5o5dA:
undetectable
1r15D-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
3 / 3 GLU A 217
ASN A 141
TRP A 376
BTB  A 604 ( 3.0A)
BTB  A 604 (-3.7A)
BTB  A 604 (-4.9A)
1.26A 1r15E-5o5dA:
undetectable
1r15E-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
3 / 3 GLU A 217
ASN A 141
TRP A 376
BTB  A 604 ( 3.0A)
BTB  A 604 (-3.7A)
BTB  A 604 (-4.9A)
1.27A 1r15F-5o5dA:
undetectable
1r15F-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 6 PHE A 418
VAL A 416
LEU A 136
PHE A 129
None
1.02A 1wrlB-5o5dA:
undetectable
1wrlB-5o5dA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)
5o5d GLUCANASE
(Trichoderma
atroviride)
3 / 3 GLY A 168
ARG A  39
TYR A 109
None
0.81A 2opxA-5o5dA:
undetectable
2opxA-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
5 / 12 GLY A 207
ASP A 173
VAL A 363
GLY A 170
SER A 184
None
BTB  A 604 (-3.7A)
None
None
None
1.05A 3k13A-5o5dA:
undetectable
3k13A-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
5 / 12 GLY A 207
ASP A 173
VAL A 363
GLY A 170
SER A 184
None
BTB  A 604 (-3.7A)
None
None
None
1.08A 3k13B-5o5dA:
undetectable
3k13B-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
5 / 12 GLY A 207
ASP A 173
VAL A 363
GLY A 170
SER A 184
None
BTB  A 604 (-3.7A)
None
None
None
1.07A 3k13C-5o5dA:
undetectable
3k13C-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
3 / 3 TYR A 158
GLY A 154
ASP A 152
None
0.59A 3ou6C-5o5dA:
undetectable
3ou6C-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 6 GLN A 312
TYR A 303
GLN A 305
ILE A 288
None
0.65A 3peoG-5o5dA:
undetectable
3peoG-5o5dA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 5 TYR A 266
THR A 272
PHE A 273
LEU A 268
CL  A 611 (-4.7A)
None
None
GOL  A 609 (-4.4A)
1.35A 3qelC-5o5dA:
undetectable
3qelC-5o5dA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 8 ASP A 214
GLY A 260
GLU A 217
ARG A 251
BTB  A 604 ( 3.4A)
None
BTB  A 604 ( 3.0A)
None
1.00A 3s3nA-5o5dA:
undetectable
3s3nA-5o5dA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 8 TYR A 145
LEU A 377
MET A 374
TRP A 376
BTB  A 604 (-3.8A)
None
None
BTB  A 604 (-4.9A)
1.04A 3uzzB-5o5dA:
undetectable
3uzzB-5o5dA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 4 LEU A 136
GLY A 142
MET A 374
PHE A  95
None
1.46A 3vaqB-5o5dA:
undetectable
3vaqB-5o5dA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
5 / 11 GLY A 170
ALA A 165
GLY A 153
MET A 149
VAL A 361
None
1.33A 4c5lA-5o5dA:
undetectable
4c5lA-5o5dA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
5 / 10 GLY A 170
ALA A 165
GLY A 153
MET A 149
VAL A 361
None
1.31A 4c5lD-5o5dA:
undetectable
4c5lD-5o5dA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IPM_A_ACTA503_0
(GH7 FAMILY PROTEIN)
5o5d GLUCANASE
(Trichoderma
atroviride)
9 / 9 ASN A 141
ALA A 143
TYR A 145
TYR A 171
ASP A 173
GLU A 212
ASP A 214
GLU A 217
TRP A 367
BTB  A 604 (-3.7A)
BTB  A 604 (-3.5A)
BTB  A 604 (-3.8A)
None
BTB  A 604 (-3.7A)
BTB  A 604 (-2.7A)
BTB  A 604 ( 3.4A)
BTB  A 604 ( 3.0A)
GOL  A 607 ( 3.5A)
0.50A 4ipmA-5o5dA:
61.9
4ipmA-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
3 / 3 SER A 342
ASP A 259
GLN A 175
None
None
BTB  A 604 (-3.8A)
0.80A 4oltA-5o5dA:
undetectable
4oltB-5o5dA:
undetectable
4oltA-5o5dA:
15.90
4oltB-5o5dA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 5 TYR A 171
SER A 365
ASP A 214
ASP A 262
None
BTB  A 604 ( 4.9A)
BTB  A 604 ( 3.4A)
GOL  A 608 (-4.6A)
1.05A 4qtuB-5o5dA:
undetectable
4qtuB-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
3 / 3 GLN A 175
SER A 342
ASP A 259
BTB  A 604 (-3.8A)
None
None
0.76A 4qwpA-5o5dA:
undetectable
4qwpB-5o5dA:
undetectable
4qwpA-5o5dA:
15.90
4qwpB-5o5dA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)
5o5d GLUCANASE
(Trichoderma
atroviride)
5 / 12 ILE A 421
VAL A 290
VAL A 291
LEU A 362
THR A 429
None
1.22A 5bykA-5o5dA:
undetectable
5bykA-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)
5o5d GLUCANASE
(Trichoderma
atroviride)
5 / 11 GLN A 186
ASP A 150
TYR A 171
PRO A 177
LEU A 180
None
1.20A 5jh7B-5o5dA:
undetectable
5jh7B-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)
5o5d GLUCANASE
(Trichoderma
atroviride)
5 / 11 GLN A 186
ASP A 150
TYR A 171
PRO A 177
LEU A 180
None
1.16A 5jh7D-5o5dA:
undetectable
5jh7D-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 8 GLY A 245
GLN A 335
ASP A 257
ASP A 173
None
None
None
BTB  A 604 (-3.7A)
1.04A 5vlmB-5o5dA:
undetectable
5vlmB-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 7 GLY A 244
GLN A 335
ASP A 257
ASP A 173
None
None
None
BTB  A 604 (-3.7A)
1.10A 5vlmE-5o5dA:
undetectable
5vlmE-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)
5o5d GLUCANASE
(Trichoderma
atroviride)
4 / 7 GLY A 245
GLN A 335
ASP A 257
ASP A 173
None
None
None
BTB  A 604 (-3.7A)
1.16A 5vlmE-5o5dA:
undetectable
5vlmE-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)
5o5d GLUCANASE
(Trichoderma
atroviride)
5 / 12 ALA A 112
GLY A  30
LYS A  31
GLY A 153
ASP A 114
None
1.12A 5wwsB-5o5dA:
undetectable
5wwsB-5o5dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H0G_B_Y70B502_0
(PROTEIN CEREBLON
ZINC FINGER PROTEIN
692)
5o5d GLUCANASE
(Trichoderma
atroviride)
5 / 11 ASN A 188
HIS A 206
GLU A 190
TRP A 192
GLN A 186
None
NI  A 603 ( 3.1A)
BTB  A 605 ( 4.7A)
None
None
1.44A 6h0gB-5o5dA:
0.0
6h0gC-5o5dA:
undetectable
6h0gB-5o5dA:
17.98
6h0gC-5o5dA:
18.18