SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o5s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G70_B_SAMB2002_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	5o5s	RNASE ADAPTER PROTEIN RAPZ (Escherichia coli)	5 / 12	LEU A 209 ASP A 202 ALA A 262 PHE A 164 VAL A 255	None	1.37A	2g70B-5o5sA: undetectable	2g70B-5o5sA: 17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A25_A_SAMA279_0 (UNCHARACTERIZED PROTEIN PH0793)	5o5s	RNASE ADAPTER PROTEIN RAPZ (Escherichia coli)	5 / 12	PHE A 167 ILE A 245 ASP A 178 THR A 242 PHE A 169	None	1.33A	3a25A-5o5sA: undetectable	3a25A-5o5sA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ARR_A_PNXA607_1 (CHITINASE A)	5o5s	RNASE ADAPTER PROTEIN RAPZ (Escherichia coli)	4 / 7	SER A 166 HIS A 276 THR A 199 LEU A 201	None	1.20A	3arrA-5o5sA: undetectable	3arrA-5o5sA: 12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AXD_A_RBVA502_2 (ADENOSYLHOMOCYSTEINA SE)	5o5s	RNASE ADAPTER PROTEIN RAPZ (Escherichia coli)	3 / 3	THR A 222 HIS A 252 LEU A 209	None MLI A 301 (-3.7A) None	0.68A	5axdA-5o5sA: undetectable	5axdA-5o5sA: 15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IEO_A_VDYA206_1 (CDL2.3A)	5o5s	RNASE ADAPTER PROTEIN RAPZ (Escherichia coli)	5 / 12	LEU A 261 PHE A 265 LEU A 233 LEU A 160 PHE A 164	None	1.32A	5ieoA-5o5sA: undetectable	5ieoA-5o5sA: 22.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2G70_B_SAMB2002_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","5o5s","RNASE ADAPTER PROTEIN RAPZ","Escherichia coli",5,"LEU A 209;ASP A 202;ALA A 262;PHE A 164;VAL A 255","None","1.37A","2g70B-5o5sA:undetectable","2g70B-5o5sA:17.89"],["3A25_A_SAMA279_0","UNCHARACTERIZED PROTEIN PH0793","5o5s","RNASE ADAPTER PROTEIN RAPZ","Escherichia coli",5,"PHE A 167;ILE A 245;ASP A 178;THR A 242;PHE A 169","None","1.33A","3a25A-5o5sA:undetectable","3a25A-5o5sA:16.67"],["3ARR_A_PNXA607_1","CHITINASE A","5o5s","RNASE ADAPTER PROTEIN RAPZ","Escherichia coli",4,"SER A 166;HIS A 276;THR A 199;LEU A 201","None","1.20A","3arrA-5o5sA:undetectable","3arrA-5o5sA:12.61"],["5AXD_A_RBVA502_2","ADENOSYLHOMOCYSTEINASE","5o5s","RNASE ADAPTER PROTEIN RAPZ","Escherichia coli",3,"THR A 222;HIS A 252;LEU A 209","None;MLI A 301 (-3.7A);None","0.68A","5axdA-5o5sA:undetectable","5axdA-5o5sA:15.35"],["5IEO_A_VDYA206_1","CDL2.3A","5o5s","RNASE ADAPTER PROTEIN RAPZ","Escherichia coli",5,"LEU A 261;PHE A 265;LEU A 233;LEU A 160;PHE A 164","None","1.32A","5ieoA-5o5sA:undetectable","5ieoA-5o5sA:22.52"]]