SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o63'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)		 5o63 RESTRICTION
ENDONUCLEASE UBALAI
(unidentified) 		5 / 12 ARG A 158
ILE A 148
GLY A 145
ALA A 141
LEU A 108
 None
 1.03A 1r9oA-5o63A:
undetectable		 1r9oA-5o63A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 5o63 RESTRICTION
ENDONUCLEASE UBALAI
(unidentified) 		4 / 7 ARG A 107
ASN A  32
THR A  93
GLY A  36
 None
 0.92A 2f6dA-5o63A:
undetectable		 2f6dA-5o63A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5o63 RESTRICTION
ENDONUCLEASE UBALAI
(unidentified) 		5 / 10 VAL A 156
ALA A 147
ILE A 148
LEU A 154
PHE A 144
 None
 1.24A 3fl9A-5o63A:
undetectable		 3fl9A-5o63A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5o63 RESTRICTION
ENDONUCLEASE UBALAI
(unidentified) 		5 / 11 ALA A   8
VAL A  12
ILE A 160
LEU A 112
ALA A  22
 None
 1.11A 3kw2A-5o63A:
undetectable		 3kw2A-5o63A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5o63 RESTRICTION
ENDONUCLEASE UBALAI
(unidentified) 		5 / 12 PHE A 140
PHE A  49
GLY A 122
ALA A 114
ILE A 160
 None
 1.33A 3ld6B-5o63A:
undetectable		 3ld6B-5o63A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_A_ACTA404_0
(PROTON-GATED ION
CHANNEL)		 5o63 RESTRICTION
ENDONUCLEASE UBALAI
(unidentified) 		4 / 4 LEU A  11
ILE A 110
ARG A 135
TYR A   7
 None
 1.42A 4zzbA-5o63A:
undetectable		 4zzbA-5o63A:
19.94