SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o64'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 5o64 REACTION CENTER
PROTEIN H CHAIN
(Blastochloris
viridis) 		3 / 3 VAL H  28
VAL H  23
TRP H  25
 None
 0.96A 1w5uC-5o64H:
undetectable
1w5uD-5o64H:
undetectable		 1w5uC-5o64H:
6.40
1w5uD-5o64H:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 5o64 REACTION CENTER
PROTEIN H CHAIN
(Blastochloris
viridis) 		3 / 3 VAL H  23
TRP H  25
VAL H  28
 None
 0.82A 2izqA-5o64H:
undetectable
2izqB-5o64H:
undetectable		 2izqA-5o64H:
6.40
2izqB-5o64H:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 5o64 REACTION CENTER
PROTEIN H CHAIN
(Blastochloris
viridis) 		5 / 10 TYR H 179
ILE H 145
ASP H 151
VAL H 150
LEU H 198
 None
 1.29A 3ay0A-5o64H:
undetectable		 3ay0A-5o64H:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 5o64 REACTION CENTER
PROTEIN H CHAIN
(Blastochloris
viridis) 		3 / 3 VAL H  28
VAL H  23
TRP H  25
 None
 0.91A 3l8lA-5o64H:
undetectable
3l8lB-5o64H:
undetectable		 3l8lA-5o64H:
6.40
3l8lB-5o64H:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 5o64 REACTION CENTER
PROTEIN H CHAIN
(Blastochloris
viridis) 		3 / 3 VAL H  28
VAL H  23
TRP H  25
 None
 0.96A 3l8lC-5o64H:
undetectable
3l8lD-5o64H:
undetectable		 3l8lC-5o64H:
6.40
3l8lD-5o64H:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5o64 REACTION CENTER
PROTEIN H CHAIN
(Blastochloris
viridis) 		5 / 7 GLU H 234
ILE H 230
GLU H 235
HIS H  72
VAL H  76
 None
 1.29A 4a97A-5o64H:
undetectable		 4a97A-5o64H:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5o64 REACTION CENTER
PROTEIN H CHAIN
(Blastochloris
viridis) 		5 / 12 GLU H 234
ILE H 230
GLU H 235
HIS H  72
VAL H  76
 None
 1.20A 4a97B-5o64H:
undetectable
4a97C-5o64H:
undetectable		 4a97B-5o64H:
20.75
4a97C-5o64H:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5o64 REACTION CENTER
PROTEIN H CHAIN
(Blastochloris
viridis) 		5 / 7 GLU H 234
ILE H 230
GLU H 235
HIS H  72
VAL H  76
 None
 1.20A 4a97D-5o64H:
undetectable		 4a97D-5o64H:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 5o64 REACTION CENTER
PROTEIN H CHAIN
(Blastochloris
viridis) 		3 / 3 PRO H 114
TYR H 248
GLY H 245
 None
 0.70A 4g2zA-5o64H:
undetectable		 4g2zA-5o64H:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5o64 REACTION CENTER
PROTEIN H CHAIN
(Blastochloris
viridis) 		4 / 6 GLN H 229
VAL H 135
ALA H 140
THR H 141
 None
 1.01A 6cduB-5o64H:
undetectable
6cduC-5o64H:
undetectable		 6cduB-5o64H:
22.12
6cduC-5o64H:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 5o64 REACTION CENTER
PROTEIN H CHAIN
(Blastochloris
viridis) 		4 / 4 LEU H 183
ASP H 151
PRO H 152
ARG H 153
 None
 1.13A 6fgdA-5o64H:
undetectable		 6fgdA-5o64H:
19.29