SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o67'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 5o67 FAPF
(Pseudomonas
sp.
UK4) 		3 / 3 ARG B 199
VAL B 206
THR B 234
 None
 0.81A 2nmzA-5o67B:
undetectable		 2nmzA-5o67B:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 5o67 FAPF
(Pseudomonas
sp.
UK4) 		3 / 3 ARG B 199
VAL B 206
THR B 234
 None
 0.80A 3k4vD-5o67B:
undetectable		 3k4vD-5o67B:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 5o67 FAPF
(Pseudomonas
sp.
UK4) 		5 / 12 ASN B  97
ALA B 374
ALA B 375
PHE B 110
LEU B 379
 None
 1.03A 3p2kC-5o67B:
undetectable		 3p2kC-5o67B:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5o67 FAPF
(Pseudomonas
sp.
UK4) 		5 / 12 PHE B 102
GLY B 104
GLY B 101
SER B 100
SER B 334
 None
 1.24A 3sueD-5o67B:
undetectable		 3sueD-5o67B:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1224_0
(THAUMATIN-LIKE
PROTEIN)		 5o67 FAPF
(Pseudomonas
sp.
UK4) 		4 / 5 SER B 196
GLU B 176
THR B 178
ASP B 148
 None
LDA  B 502 ( 4.9A)
None
LDA  B 502 (-4.1A)
 1.09A 3zs3A-5o67B:
undetectable		 3zs3A-5o67B:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 5o67 FAPF
(Pseudomonas
sp.
UK4) 		3 / 3 VAL B 274
TYR B  96
ALA B  99
 None
 0.54A 4ybnA-5o67B:
undetectable		 4ybnA-5o67B:
22.51