SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o6t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_B_DVAB35_0
(UBIQUITIN)		 5o6t POLYUBIQUITIN-B
(Homo
sapiens) 		4 / 6 GLN C  31
GLU C  34
ILE C  36
PRO C  37
 None
 0.48A 2fcnA-5o6tC:
12.2
2fcnB-5o6tC:
12.1		 2fcnA-5o6tC:
72.15
2fcnB-5o6tC:
72.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 5o6t E3 UBIQUITIN-PROTEIN
LIGASE XIAP
(Homo
sapiens) 		4 / 5 ILE A 460
LYS A 472
GLU A 476
PHE A 490
 None
 1.18A 4ac9C-5o6tA:
undetectable		 4ac9C-5o6tA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5o6t E3 UBIQUITIN-PROTEIN
LIGASE XIAP
(Homo
sapiens) 		4 / 5 ILE A 460
LYS A 472
GLU A 476
PHE A 490
 None
 1.13A 4acaC-5o6tA:
undetectable		 4acaC-5o6tA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5o6t E3 UBIQUITIN-PROTEIN
LIGASE XIAP
(Homo
sapiens) 		4 / 5 ILE A 460
LYS A 472
GLU A 476
PHE A 490
 None
 1.09A 4acbC-5o6tA:
undetectable		 4acbC-5o6tA:
8.26