SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o6u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		4 / 8 SER F 166
ARG F 170
ALA F 140
LEU F 139
 None
 0.93A 2o01A-5o6uF:
undetectable		 2o01A-5o6uF:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		5 / 12 GLY F 137
ILE F 242
LEU F 223
MET F 232
TYR F 259
 None
 1.34A 3cs8A-5o6uF:
undetectable		 3cs8A-5o6uF:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		4 / 7 VAL F 126
PHE F 255
LEU F 219
ILE F 242
 None
 1.01A 3rfmA-5o6uF:
undetectable		 3rfmA-5o6uF:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		4 / 7 ASN C  25
LEU C  43
GLY C  48
TYR C  49
 None
 0.88A 4cp3A-5o6uC:
undetectable
4cp3B-5o6uC:
undetectable		 4cp3A-5o6uC:
19.35
4cp3B-5o6uC:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		4 / 6 ASN C 230
ASP C 188
THR C 236
VAL C 232
 None
 1.02A 4yoaA-5o6uC:
undetectable		 4yoaA-5o6uC:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		5 / 12 LEU C 210
VAL C 108
GLY C 114
ARG C 128
ILE C 185
 None
 1.09A 5b8hA-5o6uC:
undetectable
5b8hB-5o6uC:
undetectable		 5b8hA-5o6uC:
19.94
5b8hB-5o6uC:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_1
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		3 / 3 ASP C 188
GLU C 240
SER C 124
 None
 0.72A 5bw4B-5o6uC:
undetectable		 5bw4B-5o6uC:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		5 / 10 TYR F  81
VAL F 301
ILE F 299
LEU F  58
PHE F  82
 None
 0.93A 5hw8C-5o6uF:
undetectable
5hw8H-5o6uF:
undetectable		 5hw8C-5o6uF:
16.94
5hw8H-5o6uF:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		5 / 11 TYR F  81
VAL F 301
ILE F 299
ILE F 334
PHE F  82
 None
 1.12A 5hw8E-5o6uF:
undetectable		 5hw8E-5o6uF:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		5 / 12 TYR F  81
VAL F 301
ILE F 299
ILE F 334
PHE F  82
 None
 1.10A 5hw8B-5o6uF:
undetectable
5hw8F-5o6uF:
undetectable
5hw8G-5o6uF:
undetectable		 5hw8B-5o6uF:
16.94
5hw8F-5o6uF:
16.94
5hw8G-5o6uF:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		5 / 11 TYR F  81
VAL F 301
ILE F 299
ILE F 334
PHE F  82
 None
 1.02A 5hw8G-5o6uF:
undetectable		 5hw8G-5o6uF:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		5 / 12 LEU C  89
PRO C 131
SER C 130
ILE C 112
LEU C 247
 None
None
U  A  18 ( 4.6A)
None
None
 1.28A 5ljbA-5o6uC:
undetectable		 5ljbA-5o6uC:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		5 / 12 PRO C 131
SER C 130
ARG C 117
ILE C 112
LEU C 247
 None
U  A  18 ( 4.6A)
A  A  20 ( 3.4A)
None
None
 1.26A 5ljbA-5o6uC:
undetectable		 5ljbA-5o6uC:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		5 / 12 LEU C  89
PRO C 131
SER C 130
ILE C 112
LEU C 247
 None
None
U  A  18 ( 4.6A)
None
None
 1.27A 5ljcA-5o6uC:
undetectable		 5ljcA-5o6uC:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5o6u UNCHARACTERIZED
PROTEIN
(Shewanella
putrefaciens) 		6 / 12 LEU C 132
PRO C 131
SER C 130
ARG C 117
ILE C 112
LEU C 247
 None
None
U  A  18 ( 4.6A)
A  A  20 ( 3.4A)
None
None
 1.43A 5ljcA-5o6uC:
undetectable		 5ljcA-5o6uC:
18.59