SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
3 / 3 TRP A  44
ALA A  47
VAL A 141
None
0.97A 1bdwA-5o6vA:
undetectable
1bdwB-5o6vA:
undetectable
1bdwA-5o6vA:
undetectable
1bdwB-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
5 / 9 ILE A 137
LEU A  45
VAL A 192
GLY A 191
LEU A 283
None
1.18A 1e7bA-5o6vA:
undetectable
1e7bA-5o6vA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
4 / 4 THR A 172
LEU A 184
VAL A 292
LEU A  23
None
1.05A 1fbmB-5o6vA:
undetectable
1fbmB-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)
5o6v ENVELOPE PROTEIN
SMALL ENVELOPE
PROTEIN M

(Tick-borne
encephalitis
virus;
Tick-borne
encephalitis
virus)
5 / 12 GLY A 468
ALA A 483
LEU A 482
LEU D  52
MET A 476
None
1.16A 1i9gA-5o6vA:
undetectable
1i9gA-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
4 / 6 HIS A 282
THR A 140
TYR A 139
HIS A 275
None
1.50A 2eimA-5o6vA:
2.0
2eimC-5o6vA:
undetectable
2eimA-5o6vA:
undetectable
2eimC-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5o6v FAB 19/1786 - HEAVY
CHAIN

(Mus
musculus)
4 / 5 TYR H  95
MET H  93
THR H 114
LEU H 115
None
1.44A 2eimJ-5o6vH:
undetectable
2eimJ-5o6vH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5o6v FAB 19/1786 - HEAVY
CHAIN

(Mus
musculus)
4 / 5 TYR H  95
MET H  93
THR H 114
LEU H 115
None
1.44A 2eimW-5o6vH:
undetectable
2eimW-5o6vH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
3 / 3 SER A 397
HIS A 323
ASP A  10
None
0.55A 2wa2B-5o6vA:
undetectable
2wa2B-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)
5o6v FAB 19/1786 - HEAVY
CHAIN

(Mus
musculus)
4 / 5 TYR H  95
MET H  93
THR H 114
LEU H 115
None
1.42A 3ag2J-5o6vH:
undetectable
3ag2J-5o6vH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)
5o6v FAB 19/1786 - HEAVY
CHAIN

(Mus
musculus)
4 / 5 TYR H  95
MET H  93
THR H 114
LEU H 115
None
1.43A 3ag4J-5o6vH:
undetectable
3ag4J-5o6vH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
5 / 12 GLY A 417
ALA A 420
ASP A 422
GLY A 191
VAL A 192
None
0.71A 3cyxB-5o6vA:
undetectable
3cyxB-5o6vA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
5 / 12 THR A 359
VAL A 385
ALA A 355
THR A 313
ILE A 364
None
1.25A 3dl9B-5o6vA:
undetectable
3dl9B-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)
5o6v FAB 19/1786 - HEAVY
CHAIN

(Mus
musculus)
3 / 3 SER H 168
SER H 167
HIS H 171
None
0.78A 3mzeA-5o6vH:
undetectable
3mzeA-5o6vH:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)
5o6v FAB 19/1786 - HEAVY
CHAIN

(Mus
musculus)
3 / 3 SER H 185
SER H 186
HIS H 206
None
0.81A 3mzeA-5o6vH:
undetectable
3mzeA-5o6vH:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
5 / 9 GLY A 417
ALA A 420
ASP A 422
GLY A 191
VAL A 192
None
0.80A 3oxvA-5o6vA:
undetectable
3oxvA-5o6vA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
5 / 9 GLY A 417
ALA A 420
ASP A 422
GLY A 191
VAL A 192
None
0.88A 3oxvC-5o6vA:
undetectable
3oxvC-5o6vA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
5 / 10 GLY A 417
ALA A 420
ASP A 422
GLY A 191
VAL A 192
None
0.80A 3oxwA-5o6vA:
undetectable
3oxwA-5o6vA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
5 / 10 GLY A 417
ALA A 420
ASP A 422
GLY A 191
VAL A 192
None
0.75A 3oxwC-5o6vA:
undetectable
3oxwC-5o6vA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)
5o6v ENVELOPE PROTEIN
SMALL ENVELOPE
PROTEIN M

(Tick-borne
encephalitis
virus)
4 / 5 PHE A 449
ALA D  45
THR D  48
LEU A 460
None
1.21A 3t3zC-5o6vA:
undetectable
3t3zC-5o6vA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)
5o6v ENVELOPE PROTEIN
SMALL ENVELOPE
PROTEIN M

(Tick-borne
encephalitis
virus)
5 / 11 THR D  53
VAL D  49
LEU A 460
VAL A 462
PHE A 449
None
1.39A 3tbgA-5o6vD:
undetectable
3tbgA-5o6vD:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC2_1
(CYTOCHROME P450 2D6)
5o6v ENVELOPE PROTEIN
SMALL ENVELOPE
PROTEIN M

(Tick-borne
encephalitis
virus)
5 / 10 THR D  53
VAL D  49
LEU A 460
VAL A 462
PHE A 449
None
1.41A 3tbgC-5o6vD:
undetectable
3tbgC-5o6vD:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
4 / 5 HIS A 146
SER A  40
THR A  34
ASP A  46
None
0.97A 3tm4A-5o6vA:
undetectable
3tm4A-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
4 / 5 HIS A 146
SER A  40
THR A  34
ASP A  46
None
0.99A 3tm4B-5o6vA:
undetectable
3tm4B-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
5 / 12 GLY A 177
TYR A 304
ASN A 366
GLU A 365
ASN A 367
None
1.32A 4pb1A-5o6vA:
undetectable
4pb1A-5o6vA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_A_SAMA401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
5 / 11 GLY A 369
GLY A 148
THR A 359
ASP A 149
ILE A 364
None
1.10A 4pghA-5o6vA:
undetectable
4pghA-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_D_SAMD401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
5 / 12 GLY A 369
GLY A 148
THR A 359
ASP A 149
ILE A 364
None
1.11A 4pghD-5o6vA:
undetectable
4pghD-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
5 / 12 SER A   1
ASP A  42
ILE A 358
SER A 321
THR A  32
None
1.32A 4uroD-5o6vA:
undetectable
4uroD-5o6vA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
4 / 7 ARG A 160
ASP A  42
THR A 325
GLU A 373
None
1.01A 5btdA-5o6vA:
undetectable
5btdC-5o6vA:
undetectable
5btdD-5o6vA:
undetectable
5btdA-5o6vA:
10.41
5btdC-5o6vA:
10.41
5btdD-5o6vA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
4 / 7 ARG A 160
ASP A  42
THR A 325
GLU A 373
None
1.01A 5btfA-5o6vA:
undetectable
5btfC-5o6vA:
undetectable
5btfD-5o6vA:
undetectable
5btfA-5o6vA:
10.41
5btfC-5o6vA:
10.41
5btfD-5o6vA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
4 / 8 SER A  40
THR A  34
THR A  32
PRO A 362
None
1.13A 5jhdE-5o6vA:
4.3
5jhdG-5o6vA:
4.1
5jhdE-5o6vA:
undetectable
5jhdG-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
4 / 7 GLY A 417
ALA A 420
ASP A 422
GLY A 191
None
0.66A 5kqyB-5o6vA:
undetectable
5kqyB-5o6vA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
4 / 8 THR A  32
SER A   1
THR A 325
SER A 321
None
0.93A 5l4eA-5o6vA:
undetectable
5l4eB-5o6vA:
2.8
5l4eC-5o6vA:
undetectable
5l4eD-5o6vA:
undetectable
5l4eE-5o6vA:
undetectable
5l4eA-5o6vA:
14.18
5l4eB-5o6vA:
14.18
5l4eC-5o6vA:
14.18
5l4eD-5o6vA:
14.18
5l4eE-5o6vA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
4 / 8 THR A 325
SER A 321
THR A  32
SER A   1
None
0.93A 5l4eA-5o6vA:
undetectable
5l4eB-5o6vA:
2.8
5l4eC-5o6vA:
undetectable
5l4eD-5o6vA:
undetectable
5l4eE-5o6vA:
undetectable
5l4eA-5o6vA:
14.18
5l4eB-5o6vA:
14.18
5l4eC-5o6vA:
14.18
5l4eD-5o6vA:
14.18
5l4eE-5o6vA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
3 / 3 VAL A 198
VAL A 131
GLN A  55
None
0.64A 5qgnA-5o6vA:
undetectable
5qgnA-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
3 / 3 VAL A 198
VAL A 131
GLN A  55
None
0.67A 5qh5A-5o6vA:
undetectable
5qh5A-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
3 / 3 VAL A 198
VAL A 131
GLN A  55
None
0.67A 5qhhA-5o6vA:
undetectable
5qhhA-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5o6v FAB 19/1786 - HEAVY
CHAIN

(Mus
musculus)
4 / 5 TYR H  95
MET H  93
THR H 114
LEU H 115
None
1.42A 5z86J-5o6vH:
undetectable
5z86J-5o6vH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
4 / 4 LEU A 194
ASP A 133
GLN A  50
VAL A  43
None
1.45A 6bzoF-5o6vA:
undetectable
6bzoF-5o6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
5 / 12 ILE A 358
SER A   1
PHE A  11
ASP A  42
ASP A  10
None
1.38A 6dwnB-5o6vA:
undetectable
6dwnB-5o6vA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
5o6v ENVELOPE PROTEIN
(Tick-borne
encephalitis
virus)
4 / 6 TRP A 235
ALA A 238
LEU A 241
ALA A  63
None
1.09A 6fosB-5o6vA:
undetectable
6fosB-5o6vA:
16.25