SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 5o71 UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		5 / 12 LEU A 552
ALA A 455
ALA A 459
PRO A 537
GLU A 544
 None
 1.13A 3cwkA-5o71A:
undetectable		 3cwkA-5o71A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 5o71 UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		5 / 12 GLY A 234
LEU A 685
PHE A 229
LEU A 232
GLU A 679
 None
 0.84A 3kkzA-5o71A:
undetectable		 3kkzA-5o71A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 5o71 UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		3 / 3 ARG A 244
VAL A 169
THR A 235
 None
 0.77A 3ndtA-5o71A:
undetectable		 3ndtA-5o71A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5o71 UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		4 / 7 GLY A 301
GLY A 321
VAL A 296
MET A 319
 None
 0.86A 4c5nA-5o71A:
undetectable		 4c5nA-5o71A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5o71 UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		4 / 8 GLY A 301
GLY A 321
VAL A 296
MET A 319
 None
 0.88A 4c5nC-5o71A:
undetectable		 4c5nC-5o71A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 5o71 UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		5 / 11 LEU A 597
VAL A 598
PHE A 395
LEU A 593
SER A 186
 None
 0.94A 4zbqA-5o71A:
undetectable		 4zbqA-5o71A:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5o71 UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		3 / 3 ARG A 376
PHE A 372
LEU A 393
 None
 0.52A 5x1bC-5o71A:
1.3		 5x1bC-5o71A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 5o71 UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		4 / 8 GLY A 170
LEU A 171
GLN A 185
ALA A 610
 None
 0.52A 5xu8A-5o71A:
22.6		 5xu8A-5o71A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 5o71 UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Homo
sapiens) 		3 / 3 ARG A 445
PHE A 446
GLY A 440
 None
 0.47A 6fgdA-5o71A:
undetectable		 6fgdA-5o71A:
undetectable