SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o75'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5o75 UBIQUITIN
CONJUGATION FACTOR
E4 B
(Homo
sapiens) 		4 / 8 LEU A1133
LEU A1118
THR A1138
LEU A1146
 None
 0.74A 4z90F-5o75A:
undetectable
4z90G-5o75A:
undetectable
4z90H-5o75A:
undetectable
4z90I-5o75A:
undetectable
4z90J-5o75A:
undetectable		 4z90F-5o75A:
12.04
4z90G-5o75A:
12.04
4z90H-5o75A:
12.04
4z90I-5o75A:
12.04
4z90J-5o75A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 5o75 UBIQUITIN
CONJUGATION FACTOR
E4 B
(Homo
sapiens) 		3 / 3 THR A1138
HIS A1132
ASN A1135
 None
 0.95A 5n4tA-5o75A:
undetectable		 5n4tA-5o75A:
16.16