SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o7g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		5 / 10 GLY A  37
PHE A  38
SER A 114
MET A 115
HIS A 284
 None
 0.77A 1a8uA-5o7gA:
23.7		 1a8uA-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		5 / 10 GLY A  37
PHE A  38
SER A 114
MET A 115
HIS A 284
 None
 0.77A 1a8uB-5o7gA:
23.7		 1a8uB-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		4 / 8 HIS A  64
GLY A  39
GLY A  68
ASP A  62
 None
 0.82A 1aegA-5o7gA:
undetectable		 1aegA-5o7gA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 ALA A  71
VAL A  65
TRP A  80
 None
 0.89A 1av2A-5o7gA:
undetectable
1av2B-5o7gA:
undetectable		 1av2A-5o7gA:
undetectable
1av2B-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		5 / 12 GLY A  56
ALA A  55
ILE A  49
ILE A 300
ILE A 301
 None
 0.84A 1hshC-5o7gA:
undetectable		 1hshC-5o7gA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I1E_A_DM2A3001_1
(BOTULINUM NEUROTOXIN
TYPE B)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		5 / 9 GLY A 112
HIS A 287
ARG A 293
CYH A 137
SER A 114
 None
 1.50A 1i1eA-5o7gA:
0.3		 1i1eA-5o7gA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		4 / 7 GLU A  40
PHE A 143
MET A 118
ALA A 120
 None
 1.34A 1linA-5o7gA:
undetectable		 1linA-5o7gA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 VAL A 278
ALA A 247
HIS A 284
 None
 0.79A 1q23L-5o7gA:
undetectable		 1q23L-5o7gA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 VAL A 278
ALA A 247
HIS A 284
 None
 0.73A 1q23J-5o7gA:
undetectable		 1q23J-5o7gA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 ALA A  71
VAL A  65
TRP A  80
 None
 0.87A 1w5uA-5o7gA:
undetectable
1w5uB-5o7gA:
undetectable		 1w5uA-5o7gA:
undetectable
1w5uB-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 TRP A  80
ALA A  71
VAL A  65
 None
 0.94A 1w5uA-5o7gA:
undetectable
1w5uB-5o7gA:
undetectable		 1w5uA-5o7gA:
undetectable
1w5uB-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 TRP A  80
ALA A  71
VAL A  65
 None
 0.82A 2izqC-5o7gA:
undetectable
2izqD-5o7gA:
undetectable		 2izqC-5o7gA:
undetectable
2izqD-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		4 / 8 ASP A 204
GLU A  40
HIS A  41
HIS A 287
 None
 0.72A 2q0iA-5o7gA:
undetectable		 2q0iA-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		4 / 9 ILE A 243
ARG A 121
ALA A 125
VAL A 237
 None
 1.02A 2vufB-5o7gA:
undetectable		 2vufB-5o7gA:
7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ201_1
(PROTEIN S100-A4)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		4 / 8 PHE A  38
PHE A 221
GLY A  78
PHE A 143
 None
 1.11A 3ko0B-5o7gA:
undetectable
3ko0J-5o7gA:
undetectable		 3ko0B-5o7gA:
19.23
3ko0J-5o7gA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 TRP A  80
ALA A  71
VAL A  65
 None
 0.93A 3l8lA-5o7gA:
undetectable
3l8lB-5o7gA:
undetectable		 3l8lA-5o7gA:
undetectable
3l8lB-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 TRP A  80
ALA A  71
VAL A  65
 None
 0.86A 3l8lC-5o7gA:
undetectable
3l8lD-5o7gA:
undetectable		 3l8lC-5o7gA:
undetectable
3l8lD-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		5 / 11 GLY A  56
ALA A  55
ILE A  49
ILE A 300
ILE A 301
 None
 0.82A 3s45B-5o7gA:
undetectable		 3s45B-5o7gA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		5 / 12 VAL A 253
HIS A 284
ASP A 251
GLY A  37
SER A 114
 None
 0.95A 3sufB-5o7gA:
undetectable		 3sufB-5o7gA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		4 / 5 PHE A 221
PHE A 143
ALA A 146
LEU A 218
 None
 1.19A 3t3zC-5o7gA:
undetectable		 3t3zC-5o7gA:
9.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		4 / 6 HIS A  41
GLU A 285
ASP A 189
ASP A 204
 None
 1.05A 3vywA-5o7gA:
undetectable		 3vywA-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 ARG A 121
THR A 231
TRP A 266
 None
 1.28A 4d7hA-5o7gA:
undetectable		 4d7hA-5o7gA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		5 / 11 TYR A 279
GLY A 138
SER A 117
TYR A  45
GLY A  37
 None
 1.39A 4ey7B-5o7gA:
17.0		 4ey7B-5o7gA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 ASP A  63
ARG A  43
ASP A  73
 None
 0.89A 4fp9D-5o7gA:
undetectable		 4fp9D-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 ARG A 121
THR A 231
TRP A 266
 None
 1.26A 4ug5A-5o7gA:
undetectable		 4ug5A-5o7gA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 ASP A 166
ASN A 214
PHE A 221
 None
 0.75A 5dsgB-5o7gA:
undetectable		 5dsgB-5o7gA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		5 / 12 SER A 114
PHE A 143
LEU A 173
PRO A 252
ARG A 283
 None
 1.36A 5hnxB-5o7gA:
undetectable		 5hnxB-5o7gA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		4 / 4 LEU A 150
MET A 225
ILE A 157
LEU A 218
 None
 1.40A 5nfpA-5o7gA:
undetectable		 5nfpA-5o7gA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		4 / 6 ARG A  26
ARG A  29
PHE A  57
ILE A  31
 None
 1.07A 5vceA-5o7gA:
undetectable		 5vceA-5o7gA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W8A_A_SAMA300_0
(AUTOINDUCER SYNTHASE)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		5 / 12 TRP A 176
MET A 225
VAL A 222
SER A 140
GLU A 172
 None
 1.47A 5w8aA-5o7gA:
1.1		 5w8aA-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 MET A 177
ASP A 251
ARG A  44
 None
 0.94A 5z6jA-5o7gA:
undetectable		 5z6jA-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		3 / 3 MET A 177
ASP A 251
ARG A  44
 None
 1.21A 5z6kA-5o7gA:
0.6		 5z6kA-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		5 / 12 LEU A 134
GLY A 133
GLN A  33
VAL A  99
ILE A  31
 None
 1.05A 6bxmA-5o7gA:
2.0		 6bxmA-5o7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5o7g ALPHA/BETA HYDROLASE
FAMILY PROTEIN
(Bacillus
coagulans) 		5 / 12 LEU A 134
GLY A 133
GLN A  33
VAL A  99
ILE A  31
 None
 1.05A 6bxnB-5o7gA:
2.0		 6bxnB-5o7gA:
undetectable