SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_Y_BEZY801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 BEZ-LEU-LEU)	5o7x	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11 (Saccharomyces cerevisiae)	5 / 5	PHE C 236 ILE C 247 GLY C 252 ILE C 240 LEU C 250	None	1.20A	5dzkd-5o7xC: undetectable 5dzkk-5o7xC: undetectable 5dzky-5o7xC: undetectable	5dzkd-5o7xC: 17.22 5dzkk-5o7xC: 16.60 5dzky-5o7xC: 1.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNA_A_ACTA307_0 (THIOREDOXIN REDUCTASE)	5o7x	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11 (Saccharomyces cerevisiae)	3 / 3	ARG C 17 LYS C 20 TYR C 187	None	1.37A	6gnaA-5o7xC: undetectable	6gnaA-5o7xC: 18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNB_A_ACTA307_0 (THIOREDOXIN REDUCTASE)	5o7x	RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11 (Saccharomyces cerevisiae)	3 / 3	ARG C 17 LYS C 20 TYR C 187	None	1.37A	6gnbA-5o7xC: undetectable	6gnbA-5o7xC: 18.73

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5DZK_Y_BEZY801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1;ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2;BEZ-LEU-LEU","5o7x","RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11","Saccharomyces cerevisiae",5,"PHE C 236;ILE C 247;GLY C 252;ILE C 240;LEU C 250","None","1.20A","5dzkd-5o7xC:undetectable;5dzkk-5o7xC:undetectable;5dzky-5o7xC:undetectable","5dzkd-5o7xC:17.22;5dzkk-5o7xC:16.60;5dzky-5o7xC:1.12"],["6GNA_A_ACTA307_0","THIOREDOXIN REDUCTASE","5o7x","RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11","Saccharomyces cerevisiae",3,"ARG C  17;LYS C  20;TYR C 187","None","1.37A","6gnaA-5o7xC:undetectable","6gnaA-5o7xC:18.73"],["6GNB_A_ACTA307_0","THIOREDOXIN REDUCTASE","5o7x","RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN11","Saccharomyces cerevisiae",3,"ARG C  17;LYS C  20;TYR C 187","None","1.37A","6gnbA-5o7xC:undetectable","6gnbA-5o7xC:18.73"]]