SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		3 / 3 TRP A 224
ALA A 226
VAL A 228
 None
 0.97A 1av2C-5o82A:
undetectable
1av2D-5o82A:
undetectable		 1av2C-5o82A:
undetectable
1av2D-5o82A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		4 / 7 ARG A 464
TRP A 370
ARG A  31
ASN A 355
 None
 1.29A 1f9gA-5o82A:
undetectable		 1f9gA-5o82A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		3 / 3 TRP A 224
ALA A 226
VAL A 228
 None
 0.97A 1w5uA-5o82A:
undetectable
1w5uB-5o82A:
undetectable		 1w5uA-5o82A:
undetectable
1w5uB-5o82A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		3 / 3 THR A 220
PRO A 222
PRO A 219
 None
 0.88A 2d55C-5o82A:
undetectable		 2d55C-5o82A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		3 / 3 ALA A 226
VAL A 228
TRP A 224
 None
 0.94A 2izqA-5o82A:
undetectable
2izqB-5o82A:
undetectable		 2izqA-5o82A:
undetectable
2izqB-5o82A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		3 / 3 TRP A 224
ALA A 226
VAL A 228
 None
 0.98A 2izqC-5o82A:
undetectable
2izqD-5o82A:
undetectable		 2izqC-5o82A:
undetectable
2izqD-5o82A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		4 / 6 LEU A  61
ASN A 355
ILE A 374
PHE A 378
 None
 1.13A 2jn3A-5o82A:
0.8		 2jn3A-5o82A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		5 / 10 ILE A 121
VAL A 105
GLY A  82
VAL A 159
LEU A 138
 None
 1.16A 3elzC-5o82A:
1.6		 3elzC-5o82A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		3 / 3 TYR A  68
TYR A  34
GLY A 106
 None
 0.76A 3eteB-5o82A:
undetectable
3eteD-5o82A:
undetectable
3eteF-5o82A:
undetectable		 3eteB-5o82A:
13.08
3eteD-5o82A:
13.08
3eteF-5o82A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		5 / 12 VAL A 159
ILE A 165
HIS A  28
VAL A  33
TYR A  34
 None
 1.26A 3g8iA-5o82A:
undetectable		 3g8iA-5o82A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		4 / 8 PHE A 221
SER A 268
LEU A 262
ASP A 261
 None
 1.00A 3m0wE-5o82A:
undetectable
3m0wF-5o82A:
undetectable
3m0wG-5o82A:
undetectable
3m0wH-5o82A:
undetectable		 3m0wE-5o82A:
26.26
3m0wF-5o82A:
26.26
3m0wG-5o82A:
26.26
3m0wH-5o82A:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_A_ACTA601_0
(CHOLINE OXIDASE)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		4 / 5 ILE A 107
HIS A 163
VAL A 159
ASN A 108
 None
 1.36A 3nneA-5o82A:
0.0		 3nneA-5o82A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		4 / 6 ILE A 107
HIS A 163
VAL A 159
ASN A 108
 None
 1.22A 3nneG-5o82A:
undetectable		 3nneG-5o82A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		5 / 9 LEU A 229
GLY A 212
ASP A 175
GLY A 171
VAL A 228
 None
 0.95A 3u7sA-5o82A:
undetectable		 3u7sA-5o82A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		5 / 10 HIS A 242
TYR A 244
TRP A 296
ALA A 173
GLY A  70
 None
 1.29A 4rn6A-5o82A:
undetectable		 4rn6A-5o82A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		4 / 6 VAL A 228
LEU A 241
SER A 240
ILE A 345
 None
 1.02A 5jw1A-5o82A:
undetectable		 5jw1A-5o82A:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		4 / 6 HIS A 157
ASN A 103
VAL A  86
GLN A 104
 None
 1.11A 5xdhA-5o82A:
undetectable
5xdhC-5o82A:
undetectable		 5xdhA-5o82A:
18.07
5xdhC-5o82A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		4 / 6 GLN A 104
HIS A 157
ASN A 103
VAL A  86
 None
 1.06A 5xdhA-5o82A:
undetectable
5xdhC-5o82A:
undetectable		 5xdhA-5o82A:
18.07
5xdhC-5o82A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		5 / 11 ILE A 239
ALA A 232
TYR A 188
LEU A 170
GLY A 189
 None
 1.34A 6ieyA-5o82A:
undetectable
6ieyB-5o82A:
undetectable		 6ieyA-5o82A:
undetectable
6ieyB-5o82A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		4 / 6 TYR A 244
GLU A 292
ASP A 291
CYH A 169
 None
AHR  A 600 (-2.8A)
None
None
 1.49A 6mn5A-5o82A:
undetectable		 6mn5A-5o82A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5o82 INTRACELLULAR
EXO-ALPHA-(1->5)-L-A
RABINOFURANOSIDASE
(Chaetomium
thermophilum) 		4 / 6 TYR A 244
GLU A 292
ASP A 291
CYH A 169
 None
AHR  A 600 (-2.8A)
None
None
 1.44A 6mn5C-5o82A:
undetectable		 6mn5C-5o82A:
22.47