SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 5o84 GLUTATHIONE
S-TRANSFERASE U23
(Arabidopsis
thaliana) 		4 / 4 ILE A  68
ASP A 154
LEU A 135
ARG A  96
 None
 1.46A 2a7qA-5o84A:
undetectable		 2a7qA-5o84A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 5o84 GLUTATHIONE
S-TRANSFERASE U23
(Arabidopsis
thaliana) 		3 / 3 ARG A  96
THR A 106
THR A  19
 None
 0.70A 3k2hB-5o84A:
undetectable		 3k2hB-5o84A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 5o84 GLUTATHIONE
S-TRANSFERASE U23
(Arabidopsis
thaliana) 		3 / 3 ALA A  22
VAL A  28
TRP A  78
 None
 0.84A 3l8lC-5o84A:
undetectable
3l8lD-5o84A:
undetectable		 3l8lC-5o84A:
7.08
3l8lD-5o84A:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5o84 GLUTATHIONE
S-TRANSFERASE U23
(Arabidopsis
thaliana) 		4 / 6 ARG A  18
PRO A  55
GLU A  66
SER A  67
 FMT  A 301 ( 4.8A)
FMT  A 301 (-4.4A)
FMT  A 301 (-4.2A)
FMT  A 301 (-2.6A)
 0.48A 3vlnA-5o84A:
22.9		 3vlnA-5o84A:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5o84 GLUTATHIONE
S-TRANSFERASE U23
(Arabidopsis
thaliana) 		4 / 6 LEU A   7
ILE A   5
LEU A  23
GLU A  24
 None
 0.91A 4w5nA-5o84A:
undetectable		 4w5nA-5o84A:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 5o84 GLUTATHIONE
S-TRANSFERASE U23
(Arabidopsis
thaliana) 		4 / 8 ARG A 213
VAL A 170
GLY A 218
LEU A 217
 None
 1.08A 5syjA-5o84A:
undetectable		 5syjA-5o84A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5o84 GLUTATHIONE
S-TRANSFERASE U23
(Arabidopsis
thaliana) 		4 / 5 PHE A 160
PHE A 157
LEU A 182
PHE A 179
 OMT  A  14 ( 3.8A)
None
None
None
 1.34A 5xdqC-5o84A:
undetectable
5xdqJ-5o84A:
undetectable		 5xdqC-5o84A:
17.56
5xdqJ-5o84A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 5o84 GLUTATHIONE
S-TRANSFERASE U23
(Arabidopsis
thaliana) 		4 / 7 TYR A  73
HIS A  59
LEU A  23
VAL A  28
 None
 1.20A 6g2pA-5o84A:
undetectable		 6g2pA-5o84A:
20.24