SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o8o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5o8o MITOCHONDRIAL IMPORT
RECEPTOR SUBUNIT
TOM40
(Neurospora
crassa) 		5 / 9 SER A 156
GLY A  42
ARG A 213
ALA A 182
GLY A 190
 None
 1.29A 1jb0A-5o8oA:
undetectable		 1jb0A-5o8oA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 5o8o MITOCHONDRIAL IMPORT
RECEPTOR SUBUNIT
TOM40
(Neurospora
crassa) 		4 / 6 TYR A 179
ASP A 154
PHE A  29
ARG A  33
 None
 1.16A 2a3bB-5o8oA:
undetectable		 2a3bB-5o8oA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 5o8o MITOCHONDRIAL IMPORT
RECEPTOR SUBUNIT
TOM40
(Neurospora
crassa) 		4 / 7 SER A 234
ASP A 248
SER A 222
VAL A 220
 None
 0.78A 2hdnE-5o8oA:
undetectable
2hdnF-5o8oA:
undetectable
2hdnH-5o8oA:
undetectable		 2hdnE-5o8oA:
10.64
2hdnF-5o8oA:
21.39
2hdnH-5o8oA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 5o8o MITOCHONDRIAL IMPORT
RECEPTOR SUBUNIT
TOM40
(Neurospora
crassa) 		4 / 7 SER A 222
VAL A 220
SER A 234
ASP A 248
 None
 0.78A 2hdnF-5o8oA:
undetectable
2hdnG-5o8oA:
undetectable
2hdnH-5o8oA:
undetectable		 2hdnF-5o8oA:
21.39
2hdnG-5o8oA:
10.64
2hdnH-5o8oA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 5o8o MITOCHONDRIAL IMPORT
RECEPTOR SUBUNIT
TOM40
(Neurospora
crassa) 		4 / 6 SER A 234
ASP A 248
SER A 222
VAL A 220
 None
 0.78A 2hdnI-5o8oA:
undetectable
2hdnJ-5o8oA:
undetectable
2hdnL-5o8oA:
undetectable		 2hdnI-5o8oA:
10.64
2hdnJ-5o8oA:
21.39
2hdnL-5o8oA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 5o8o MITOCHONDRIAL IMPORT
RECEPTOR SUBUNIT
TOM40
(Neurospora
crassa) 		4 / 6 SER A 222
VAL A 220
SER A 234
ASP A 248
 None
 0.86A 2hdnJ-5o8oA:
undetectable
2hdnK-5o8oA:
undetectable
2hdnL-5o8oA:
undetectable		 2hdnJ-5o8oA:
21.39
2hdnK-5o8oA:
10.64
2hdnL-5o8oA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 5o8o MITOCHONDRIAL IMPORT
RECEPTOR SUBUNIT
TOM40
(Neurospora
crassa) 		3 / 3 PHE A 155
PHE A  29
PHE A  26
 None
 0.76A 2od9A-5o8oA:
undetectable		 2od9A-5o8oA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 5o8o MITOCHONDRIAL IMPORT
RECEPTOR SUBUNIT
TOM40
(Neurospora
crassa) 		3 / 3 PHE A 155
PHE A  29
PHE A  26
 None
 0.76A 2qqgA-5o8oA:
undetectable		 2qqgA-5o8oA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5o8o MITOCHONDRIAL IMPORT
RECEPTOR SUBUNIT
TOM40
(Neurospora
crassa) 		5 / 9 SER A 156
GLY A  42
ARG A 213
ALA A 182
GLY A 190
 None
 1.30A 3pcqA-5o8oA:
undetectable		 3pcqA-5o8oA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5o8o MITOCHONDRIAL IMPORT
RECEPTOR SUBUNIT
TOM40
(Neurospora
crassa) 		4 / 4 PRO A  41
LEU A 151
ILE A 130
ARG A 128
 None
 1.23A 4f4dA-5o8oA:
undetectable		 4f4dA-5o8oA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DL9_A_ACTA214_0
(LYSOZYME C)		 5o8o MITOCHONDRIAL IMPORT
RECEPTOR SUBUNIT
TOM40
(Neurospora
crassa) 		4 / 5 GLU A 329
ASP A 332
VAL A  81
ALA A  72
 None
 1.12A 5dl9A-5o8oA:
undetectable		 5dl9A-5o8oA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5o8o MITOCHONDRIAL IMPORT
RECEPTOR SUBUNIT
TOM40
(Neurospora
crassa) 		5 / 9 SER A 156
GLY A  42
ARG A 213
ALA A 182
GLY A 190
 None
 1.30A 5l8rA-5o8oA:
undetectable		 5l8rA-5o8oA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 5o8o MITOCHONDRIAL IMPORT
RECEPTOR SUBUNIT
TOM40
(Neurospora
crassa) 		4 / 8 ASN A  40
PHE A 211
VAL A 220
TYR A 214
 None
 1.24A 6huoC-5o8oA:
undetectable
6huoD-5o8oA:
undetectable		 6huoC-5o8oA:
13.14
6huoD-5o8oA:
12.68