SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o98'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FPQ_A_SAMA1699_0
(ISOLIQUIRITIGENIN
2'-O-METHYLTRANSFERA
SE)		 5o98 ALCOHOL
DEHYDROGENASE 1
(Catharanthus
roseus) 		5 / 10 GLY A  21
ASN A  17
LEU A  28
VAL A  35
ALA A  95
 None
NAP  A 501 (-3.0A)
None
None
NAP  A 501 (-3.4A)
 1.25A 1fpqA-5o98A:
6.3		 1fpqA-5o98A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 5o98 ALCOHOL
DEHYDROGENASE 1
(Catharanthus
roseus) 		4 / 7 SER A  30
ILE A  90
ILE A  33
LYS A   9
 None
 1.00A 1sbrB-5o98A:
undetectable		 1sbrB-5o98A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5o98 ALCOHOL
DEHYDROGENASE 1
(Catharanthus
roseus) 		5 / 12 GLY A  15
ARG A  40
ASP A  67
ASN A  94
ALA A  95
 NAP  A 501 (-3.6A)
NAP  A 501 (-3.2A)
NAP  A 501 (-3.4A)
NAP  A 501 (-3.3A)
NAP  A 501 (-3.4A)
 1.03A 2bm9E-5o98A:
4.9		 2bm9E-5o98A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 5o98 ALCOHOL
DEHYDROGENASE 1
(Catharanthus
roseus) 		4 / 8 ILE A 165
ASN A 139
SER A 226
SER A 167
 NAP  A 501 (-4.4A)
None
None
NAP  A 501 ( 4.3A)
 1.16A 2zw9B-5o98A:
5.5		 2zw9B-5o98A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 5o98 ALCOHOL
DEHYDROGENASE 1
(Catharanthus
roseus) 		3 / 3 LEU A 280
VAL A  92
ARG A 161
 None
 0.85A 3b0wB-5o98A:
undetectable		 3b0wB-5o98A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 5o98 ALCOHOL
DEHYDROGENASE 1
(Catharanthus
roseus) 		6 / 12 GLY A  96
ALA A  95
VAL A  13
GLY A  19
THR A  24
PRO A 274
 NAP  A 501 (-3.8A)
NAP  A 501 (-3.4A)
None
NAP  A 501 (-3.4A)
None
None
 1.48A 3el5B-5o98A:
undetectable		 3el5B-5o98A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5o98 ALCOHOL
DEHYDROGENASE 1
(Catharanthus
roseus) 		5 / 12 THR A 147
THR A 146
THR A 143
ILE A 246
LEU A  66
 None
 1.37A 3gwxB-5o98A:
undetectable		 3gwxB-5o98A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5o98 ALCOHOL
DEHYDROGENASE 1
(Catharanthus
roseus) 		4 / 4 ASP A  47
GLY A  45
LYS A  43
GLU A  42
 None
 1.35A 3hznD-5o98A:
undetectable		 3hznD-5o98A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 5o98 ALCOHOL
DEHYDROGENASE 1
(Catharanthus
roseus) 		3 / 3 THR A 128
LYS A  18
GLU A 130
 None
NAP  A 501 (-3.9A)
None
 0.80A 3ijdB-5o98A:
undetectable		 3ijdB-5o98A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5o98 ALCOHOL
DEHYDROGENASE 1
(Catharanthus
roseus) 		4 / 5 LEU A 151
PRO A 152
LEU A 154
ILE A 162
 None
 0.88A 4klrA-5o98A:
2.7		 4klrA-5o98A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 5o98 ALCOHOL
DEHYDROGENASE 1
(Catharanthus
roseus) 		5 / 11 GLY A  45
VAL A  35
LEU A  57
LEU A  28
PHE A  22
 None
 0.98A 4zmeA-5o98A:
undetectable		 4zmeA-5o98A:
16.32