SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o99'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 5o99 SH3 AND MULTIPLE
ANKYRIN REPEAT
DOMAINS PROTEIN 3
(Rattus
norvegicus) 		5 / 12 PHE B 519
ALA B 521
VAL B 524
GLY B 510
GLU B 509
 None
 1.12A 3c6gB-5o99B:
undetectable		 3c6gB-5o99B:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5o99 SH3 AND MULTIPLE
ANKYRIN REPEAT
DOMAINS PROTEIN 3
(Rattus
norvegicus) 		4 / 5 THR B 516
GLY B 514
GLU B 495
HIS B 492
 None
 1.16A 5c0oH-5o99B:
undetectable		 5c0oH-5o99B:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 5o99 SH3 AND MULTIPLE
ANKYRIN REPEAT
DOMAINS PROTEIN 3
(Rattus
norvegicus) 		5 / 12 ALA B 521
GLU B 495
ILE B 489
TRP B 518
VAL B 499
 None
 1.41A 5vlmE-5o99B:
undetectable		 5vlmE-5o99B:
18.31