SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 8 GLN C 266
ASN C 267
TYR C 286
LEU C 303
 None
 1.05A 1hk3A-5o9cC:
undetectable		 1hk3A-5o9cC:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 8 SER C  28
SER C 341
ASN C 327
LYS C 325
 None
 1.25A 1hwiB-5o9cC:
undetectable		 1hwiB-5o9cC:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 6 ARG C 133
ASP C  90
THR C 131
ASP C 100
 None
 0.93A 2j2pE-5o9cC:
undetectable
2j2pF-5o9cC:
undetectable		 2j2pE-5o9cC:
19.49
2j2pF-5o9cC:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		3 / 3 THR C 201
LYS C 212
GLU C 203
 None
 0.96A 3ijdB-5o9cC:
undetectable		 3ijdB-5o9cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 4 GLY C  54
TYR C  53
GLY C  80
ASP C  90
 None
 0.66A 3kl3A-5o9cC:
undetectable		 3kl3A-5o9cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		3 / 3 TYR C  95
LEU C  81
LYS C  82
 None
 0.78A 3sueD-5o9cC:
undetectable		 3sueD-5o9cC:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		5 / 12 GLY C 233
GLN C 246
GLU C 269
ALA C 244
TYR C 242
 None
 1.32A 3t7sC-5o9cC:
undetectable		 3t7sC-5o9cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 6 ASP C 106
GLY C 112
ASP C 114
THR C 115
 None
 0.97A 3vqrA-5o9cC:
undetectable		 3vqrA-5o9cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 5 ASP C 106
GLY C 112
ASP C 114
THR C 115
 None
 0.99A 3vqrB-5o9cC:
undetectable		 3vqrB-5o9cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 8 LYS C  16
TYR C  35
ARG C  75
ARG C 125
 None
 0.88A 4kr4C-5o9cC:
37.2		 4kr4C-5o9cC:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 8 LYS C  16
TYR C  35
ASP C 106
ARG C 125
 None
 0.76A 4kr4C-5o9cC:
37.2		 4kr4C-5o9cC:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR8_C_DM1C401_1
(OUTER MEMBRANE
PROTEIN F)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		5 / 10 LYS C  16
TYR C  35
ARG C  75
TYR C  95
ARG C 125
 None
 0.79A 4kr8C-5o9cC:
39.0		 4kr8C-5o9cC:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 5 GLY C 215
TYR C 297
TYR C 218
GLY C 219
 None
 1.03A 5ayfA-5o9cC:
0.2		 5ayfA-5o9cC:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		5 / 10 ALA C 244
THR C 245
GLU C 269
ALA C 191
GLY C 192
 None
 0.90A 5lf3H-5o9cC:
undetectable
5lf3I-5o9cC:
undetectable		 5lf3H-5o9cC:
13.68
5lf3I-5o9cC:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		5 / 10 ALA C 244
THR C 245
GLU C 269
ALA C 191
GLY C 192
 None
 0.92A 5lf3V-5o9cC:
undetectable
5lf3W-5o9cC:
undetectable		 5lf3V-5o9cC:
13.68
5lf3W-5o9cC:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		5 / 11 ALA C 244
THR C 245
GLU C 269
ALA C 191
GLY C 192
 None
 0.93A 5lf7H-5o9cC:
undetectable
5lf7I-5o9cC:
undetectable		 5lf7H-5o9cC:
undetectable
5lf7I-5o9cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		5 / 11 ALA C 244
THR C 245
GLU C 269
ALA C 191
GLY C 192
 None
 0.93A 5lf7V-5o9cC:
undetectable
5lf7W-5o9cC:
undetectable		 5lf7V-5o9cC:
undetectable
5lf7W-5o9cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 4 SER C 180
ALA C 194
GLN C 123
THR C 102
 None
 1.46A 5n0rA-5o9cC:
undetectable		 5n0rA-5o9cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 4 SER C 180
ALA C 194
GLN C 123
THR C 102
 None
 1.45A 5n0sA-5o9cC:
undetectable		 5n0sA-5o9cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 4 SER C 180
ALA C 194
GLN C 123
THR C 102
 None
 1.45A 5n0wA-5o9cC:
undetectable		 5n0wA-5o9cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 4 SER C 180
ALA C 194
GLN C 123
THR C 102
 None
 1.48A 5n0xA-5o9cC:
undetectable		 5n0xA-5o9cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		3 / 3 VAL C 129
ALA C 126
GLN C 149
 None
 0.62A 6gb9A-5o9cC:
undetectable		 6gb9A-5o9cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 8 ASP C 225
HIS C 226
ASP C 161
GLU C 160
 None
 1.21A 6mn4A-5o9cC:
undetectable		 6mn4A-5o9cC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5o9c OSMOPORIN OMP36
(Klebsiella
aerogenes) 		4 / 8 ASP C 225
HIS C 226
ASP C 202
GLU C 160
 None
 1.22A 6mn4C-5o9cC:
undetectable		 6mn4C-5o9cC:
undetectable