SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o9e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
(Chaetomium
thermophilum) 		4 / 8 PHE A 103
ILE A 107
HIS A 143
LEU A 167
 None
 0.69A 1fslB-5o9eA:
undetectable		 1fslB-5o9eA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
(Chaetomium
thermophilum) 		4 / 7 PHE A 212
PHE A 111
HIS A 241
VAL A 239
 None
 0.94A 1lh6A-5o9eA:
undetectable		 1lh6A-5o9eA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
PROTEIN
(Chaetomium
thermophilum) 		6 / 12 LEU A 200
GLU B 505
LEU B 502
ILE A 268
GLY B 518
LEU B 517
 None
 1.22A 1qknA-5o9eA:
undetectable		 1qknA-5o9eA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
PROTEIN
(Chaetomium
thermophilum) 		6 / 12 LEU A 200
THR A 198
LEU B 502
ILE A 268
GLY B 518
LEU B 517
 None
 1.49A 1qknA-5o9eA:
undetectable		 1qknA-5o9eA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
(Chaetomium
thermophilum) 		3 / 3 ASP A  75
TYR A  77
LYS A 209
 None
 1.19A 2othA-5o9eA:
undetectable		 2othA-5o9eA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
(Chaetomium
thermophilum) 		5 / 12 LEU A 167
PHE A 230
ILE A 207
ILE A 154
LEU A 191
 None
 1.34A 3w67D-5o9eA:
undetectable		 3w67D-5o9eA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
(Chaetomium
thermophilum) 		4 / 6 ILE A 107
LEU A 142
ARG A 260
THR A 262
 None
 1.18A 3wg7A-5o9eA:
undetectable
3wg7J-5o9eA:
undetectable		 3wg7A-5o9eA:
16.12
3wg7J-5o9eA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
PROTEIN
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 7 ILE B 541
ARG A 240
ARG A 260
GLU B 535
 None
 0.89A 4zzbC-5o9eB:
undetectable
4zzbD-5o9eB:
undetectable		 4zzbC-5o9eB:
16.51
4zzbD-5o9eB:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
PROTEIN
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 ILE B 541
ARG A 240
ARG A 260
GLU B 535
 None
 0.99A 4zzcA-5o9eB:
undetectable
4zzcB-5o9eB:
undetectable		 4zzcA-5o9eB:
16.51
4zzcB-5o9eB:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
PROTEIN
(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		4 / 6 ILE B 541
ARG A 240
ARG A 260
GLU B 535
 None
 0.96A 4zzcB-5o9eB:
undetectable
4zzcC-5o9eB:
undetectable		 4zzcB-5o9eB:
16.51
4zzcC-5o9eB:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
(Chaetomium
thermophilum) 		4 / 7 ALA A 151
THR A 150
GLU A 144
HIS A 143
 None
 1.06A 5ecnA-5o9eA:
undetectable		 5ecnA-5o9eA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
(Chaetomium
thermophilum) 		4 / 7 THR A  91
LEU A 141
ILE A 152
THR A 153
 None
 0.94A 5zsfA-5o9eA:
undetectable
5zsfB-5o9eA:
undetectable		 5zsfA-5o9eA:
19.54
5zsfB-5o9eA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 5o9e PUTATIVE U3 SMALL
NUCLEOLAR
RIBONUCLEOPROTEIN
(Chaetomium
thermophilum) 		5 / 10 LEU A 167
PRO A 259
GLU A 256
PHE A 111
VAL A  90
 None
 0.97A 6b89B-5o9eA:
undetectable		 6b89B-5o9eA:
19.10