SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		4 / 8 TRP A 255
SER A 123
ASN A 119
GLN A 259
 None
 1.14A 1ig3A-5o9hA:
undetectable
1ig3B-5o9hA:
undetectable		 1ig3A-5o9hA:
14.78
1ig3B-5o9hA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		4 / 6 VAL A 248
PHE A 211
PRO A 214
THR A 217
 OLA  A 417 ( 4.9A)
None
9P2  A 401 (-3.8A)
9P2  A 401 (-3.9A)
 1.46A 2q6oB-5o9hA:
undetectable		 2q6oB-5o9hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		5 / 12 SER A 283
ALA A  40
ILE A  96
LEU A  92
LEU A  89
 None
 0.96A 3adsB-5o9hA:
undetectable		 3adsB-5o9hA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		4 / 8 TYR A 181
LYS A 185
PRO A 103
PHE A 104
 None
 1.45A 3bjwD-5o9hA:
undetectable		 3bjwD-5o9hA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		5 / 12 ALA A  66
LEU A 127
LEU A 126
ALA A  72
TYR A 300
 OLA  A 407 ( 4.3A)
None
None
None
None
 1.06A 4lg1A-5o9hA:
undetectable		 4lg1A-5o9hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		3 / 3 ARG A 148
GLU A 326
ARG A 134
 TLA  A 402 (-3.2A)
TLA  A 402 (-3.6A)
None
 0.66A 4mwvA-5o9hA:
undetectable		 4mwvA-5o9hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		6 / 12 ILE A 130
LEU A 323
ALA A  72
TRP A  74
ILE A 299
TYR A 222
 None
None
None
None
OLA  A 414 ( 4.2A)
None
 1.46A 4psyA-5o9hA:
undetectable		 4psyA-5o9hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		5 / 12 LEU A 323
GLY A 304
ALA A 303
ILE A 299
VAL A 247
 None
None
OLA  A 414 ( 4.3A)
OLA  A 414 ( 4.2A)
None
 0.91A 4xdrA-5o9hA:
undetectable		 4xdrA-5o9hA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		5 / 11 SER A 283
ALA A  40
ILE A  96
LEU A  92
LEU A  89
 None
 1.03A 4xumB-5o9hA:
undetectable		 4xumB-5o9hA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		4 / 5 LEU A 323
TYR A 300
ALA A  79
ASN A  55
 None
 1.16A 4y03B-5o9hA:
undetectable		 4y03B-5o9hA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		4 / 8 PHE A 251
GLY A 210
LEU A 167
LEU A 163
 None
None
None
9P2  A 401 (-4.7A)
 0.88A 5hs1A-5o9hA:
undetectable		 5hs1A-5o9hA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		5 / 12 VAL A  58
LEU A 127
ALA A  79
THR A 129
ARG A 134
 None
None
None
9P2  A 401 (-4.4A)
None
 1.22A 5nd3B-5o9hA:
undetectable		 5nd3B-5o9hA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		4 / 7 LEU A 166
TRP A 161
ALA A 122
LEU A 126
 None
 1.05A 5nwvA-5o9hA:
undetectable		 5nwvA-5o9hA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		5 / 10 ILE A 124
TRP A 154
ILE A  70
ALA A 153
ALA A 158
 9P2  A 401 (-4.4A)
None
TLA  A 402 (-3.3A)
OLA  A 404 ( 4.0A)
OLA  A 416 (-3.5A)
 1.43A 5zjiB-5o9hA:
2.1		 5zjiB-5o9hA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		5 / 12 VAL A  59
VAL A 248
ASN A 292
ASN A 296
TYR A 300
 None
OLA  A 417 ( 4.9A)
None
None
None
 1.49A 6h7lA-5o9hA:
20.7		 6h7lA-5o9hA:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_B_PQNB2002_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1
(Homo
sapiens) 		5 / 9 TRP A 161
ILE A  70
ALA A 153
LEU A 156
ALA A 160
 None
TLA  A 402 (-3.3A)
OLA  A 404 ( 4.0A)
9P2  A 401 (-3.9A)
9P2  A 401 ( 3.9A)
 1.46A 6hqbB-5o9hA:
1.2		 6hqbB-5o9hA:
22.35