SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5o9j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 5o9j TRANSCRIPTION
INITIATION FACTOR
IIB,TRANSCRIPTION
INITIATION FACTOR
IIB
(Methanocaldococc
us
jannaschii) 		4 / 7 VAL A 177
VAL A  89
TYR A   4
ARG A 130
 None
 1.29A 1t46A-5o9jA:
undetectable		 1t46A-5o9jA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 5o9j TRANSCRIPTION
INITIATION FACTOR
IIB,TRANSCRIPTION
INITIATION FACTOR
IIB
(Methanocaldococc
us
jannaschii) 		5 / 12 ALA A 171
GLY A 174
GLY A 175
ASP A   3
LEU A 161
 None
 1.08A 3m6vA-5o9jA:
undetectable		 3m6vA-5o9jA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 5o9j TRANSCRIPTION
INITIATION FACTOR
IIB,TRANSCRIPTION
INITIATION FACTOR
IIB
(Methanocaldococc
us
jannaschii) 		5 / 12 ALA A 171
GLY A 174
GLY A 175
ASP A   3
LEU A 161
 None
 1.05A 3m6vB-5o9jA:
undetectable		 3m6vB-5o9jA:
15.67