SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5oac'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 5oac MAJOR CAPSID PROTEIN
(unidentified
phage) 		5 / 12 ILE A  21
LEU A  71
ILE A 121
LEU A 129
TYR A 108
 None
 1.19A 1jolA-5oacA:
undetectable		 1jolA-5oacA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 5oac MAJOR CAPSID PROTEIN
(unidentified
phage) 		3 / 3 ASP A  52
PHE A  25
VAL A  56
 None
 0.75A 1kijB-5oacA:
undetectable		 1kijB-5oacA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 5oac MAJOR CAPSID PROTEIN
(unidentified
phage) 		3 / 3 GLU A 297
LYS A 291
VAL A 293
 None
 0.90A 1l2iA-5oacA:
undetectable		 1l2iA-5oacA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5oac MAJOR CAPSID PROTEIN
(unidentified
phage) 		4 / 6 LEU A 181
LEU A 184
GLY A 185
ILE A 256
 None
 0.91A 1mt1G-5oacA:
undetectable
1mt1J-5oacA:
undetectable		 1mt1G-5oacA:
12.77
1mt1J-5oacA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5oac MAJOR CAPSID PROTEIN
(unidentified
phage) 		4 / 6 ALA A 119
ILE A 165
PRO A 166
GLU A 162
 None
 1.23A 1oniB-5oacA:
undetectable
1oniC-5oacA:
undetectable		 1oniB-5oacA:
19.02
1oniC-5oacA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 5oac MAJOR CAPSID PROTEIN
(unidentified
phage) 		4 / 6 LEU A 212
ILE A 254
ARG A 279
ILE A 191
 None
 0.60A 2q8hA-5oacA:
undetectable		 2q8hA-5oacA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5oac MAJOR CAPSID PROTEIN
(unidentified
phage) 		4 / 8 ILE A 256
LEU A 181
LEU A 184
GLY A 185
 None
 0.87A 2qqdB-5oacA:
undetectable
2qqdC-5oacA:
undetectable		 2qqdB-5oacA:
16.50
2qqdC-5oacA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 5oac MAJOR CAPSID PROTEIN
(unidentified
phage) 		4 / 8 THR A 115
PRO A 118
GLY A  20
SER A 156
 None
 1.07A 3tzfB-5oacA:
undetectable		 3tzfB-5oacA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 5oac MAJOR CAPSID PROTEIN
(unidentified
phage) 		4 / 6 PHE A  50
LYS A  40
GLY A  38
ALA A  36
 None
 0.99A 4yshB-5oacA:
undetectable		 4yshB-5oacA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5oac MAJOR CAPSID PROTEIN
(unidentified
phage) 		5 / 5 ILE A   3
LYS A  59
ILE A  58
HIS A  57
VAL A  56
 None
 1.07A 5jmnA-5oacA:
1.2		 5jmnA-5oacA:
14.61