SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ob5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR)	5ob5	FAB HEAVY CHAIN (Homo sapiens)	4 / 6	TRP H 36 MET H 81 MET H 70 LEU H 83	None	1.47A	2oz7A-5ob5H: undetectable	2oz7A-5ob5H: 18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YLQ_A_TESA1921_1 (ANDROGEN RECEPTOR)	5ob5	C-X-C MOTIF CHEMOKINE 2 (Homo sapiens)	5 / 11	LEU A 44 ASN A 22 LEU A 20 MET A 58 VAL A 59	None	1.42A	2ylqA-5ob5A: undetectable	2ylqA-5ob5A: 15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HUO_A_PNNA302_0 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	5ob5	FAB HEAVY CHAIN (Homo sapiens)	4 / 6	LEU H 195 GLY H 196 ALA H 131 PRO H 132	None	0.53A	3huoA-5ob5H: undetectable	3huoA-5ob5H: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FU8_A_ACTA304_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	5ob5	FAB HEAVY CHAIN (Homo sapiens)	3 / 3	ARG H 98 HIS H 108 TYR H 32	SO4 H 304 (-3.0A) SO4 H 303 ( 3.7A) None	0.99A	4fu8A-5ob5H: undetectable	4fu8A-5ob5H: 20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FU9_A_ACTA312_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	5ob5	FAB HEAVY CHAIN (Homo sapiens)	3 / 3	ARG H 98 HIS H 108 TYR H 32	SO4 H 304 (-3.0A) SO4 H 303 ( 3.7A) None	1.00A	4fu9A-5ob5H: undetectable	4fu9A-5ob5H: 20.91

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OZ7_A_CA4A1_2","ANDROGEN RECEPTOR","5ob5","FAB HEAVY CHAIN","Homo sapiens",4,"TRP H  36;MET H  81;MET H  70;LEU H  83","None","1.47A","2oz7A-5ob5H:undetectable","2oz7A-5ob5H:18.92"],["2YLQ_A_TESA1921_1","ANDROGEN RECEPTOR","5ob5","C-X-C MOTIF CHEMOKINE 2","Homo sapiens",5,"LEU A  44;ASN A  22;LEU A  20;MET A  58;VAL A  59","None","1.42A","2ylqA-5ob5A:undetectable","2ylqA-5ob5A:15.38"],["3HUO_A_PNNA302_0","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","5ob5","FAB HEAVY CHAIN","Homo sapiens",4,"LEU H 195;GLY H 196;ALA H 131;PRO H 132","None","0.53A","3huoA-5ob5H:undetectable","3huoA-5ob5H:21.71"],["4FU8_A_ACTA304_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","5ob5","FAB HEAVY CHAIN","Homo sapiens",3,"ARG H  98;HIS H 108;TYR H  32","SO4 H 304 (-3.0A);SO4 H 303 ( 3.7A);None","0.99A","4fu8A-5ob5H:undetectable","4fu8A-5ob5H:20.91"],["4FU9_A_ACTA312_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","5ob5","FAB HEAVY CHAIN","Homo sapiens",3,"ARG H  98;HIS H 108;TYR H  32","SO4 H 304 (-3.0A);SO4 H 303 ( 3.7A);None","1.00A","4fu9A-5ob5H:undetectable","4fu9A-5ob5H:20.91"]]