SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5obn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5obn RNA-BINDING PROTEIN
40
(Homo
sapiens) 		5 / 12 GLY A 488
GLY A 397
VAL A 497
VAL A 409
PHE A 410
 None
 0.91A 2zulA-5obnA:
undetectable		 2zulA-5obnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5obn RNA-BINDING PROTEIN
40
(Homo
sapiens) 		5 / 12 GLY A 488
GLY A 397
VAL A 497
VAL A 409
PHE A 410
 None
 0.87A 3dmfA-5obnA:
undetectable		 3dmfA-5obnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 5obn RNA-BINDING PROTEIN
40
(Homo
sapiens) 		5 / 12 GLY A 488
GLY A 397
VAL A 497
VAL A 409
PHE A 410
 None
 0.87A 3dmhA-5obnA:
undetectable		 3dmhA-5obnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 5obn RNA-BINDING PROTEIN
40
(Homo
sapiens) 		3 / 3 GLU A 512
GLU A 476
ASN A 475
 None
 0.89A 3lp9B-5obnA:
undetectable
3lp9D-5obnA:
undetectable		 3lp9B-5obnA:
14.81
3lp9D-5obnA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 5obn RNA-BINDING PROTEIN
40
(Homo
sapiens) 		4 / 6 LEU A 459
LEU A 436
ILE A 439
MET A 496
 None
 0.84A 4do3B-5obnA:
undetectable		 4do3B-5obnA:
8.81