SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5obw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 6 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.13A 1c8lA-5obwA:
undetectable		 1c8lA-5obwA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 6 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.09A 1gfzA-5obwA:
undetectable		 1gfzA-5obwA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 6 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.10A 1l5qA-5obwA:
undetectable		 1l5qA-5obwA:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 6 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.08A 1l5qB-5obwA:
undetectable		 1l5qB-5obwA:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 6 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.05A 1l7xA-5obwA:
undetectable		 1l7xA-5obwA:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 6 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.08A 1l7xB-5obwA:
undetectable		 1l7xB-5obwA:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 GLY A 208
GLY A 180
GLY A 181
LEU A 206
ASN A 213
 ADP  A 402 (-3.3A)
ADP  A 402 (-3.5A)
None
None
None
 0.85A 1qzzA-5obwA:
undetectable		 1qzzA-5obwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 LEU A 332
VAL A 333
SER A 335
VAL A 185
LEU A 187
 None
 1.24A 1rk3A-5obwA:
undetectable		 1rk3A-5obwA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 LEU A 103
LEU A 106
ALA A 110
LEU A  31
ILE A 123
 None
 1.06A 1s9pA-5obwA:
undetectable		 1s9pA-5obwA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 LEU A 103
LEU A 106
ALA A 110
LEU A  31
ILE A 123
 None
 1.06A 1s9pD-5obwA:
undetectable		 1s9pD-5obwA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 GLY A 208
GLY A 180
GLY A 181
LEU A 206
ASN A 213
 ADP  A 402 (-3.3A)
ADP  A 402 (-3.5A)
None
None
None
 0.93A 1xdsA-5obwA:
undetectable		 1xdsA-5obwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 GLY A 208
GLY A 180
GLY A 181
LEU A 206
ASN A 213
 ADP  A 402 (-3.3A)
ADP  A 402 (-3.5A)
None
None
None
 0.89A 1xdsB-5obwA:
undetectable		 1xdsB-5obwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 8 THR A 267
VAL A 274
VAL A 276
ALA A 224
 None
 1.13A 2ij7C-5obwA:
undetectable		 2ij7C-5obwA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		3 / 3 TYR A 128
GLU A 133
ASN A  79
 GOL  A 412 ( 3.9A)
GOL  A 410 ( 4.9A)
None
 1.01A 2y7hC-5obwA:
undetectable		 2y7hC-5obwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 5 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.14A 3bcrA-5obwA:
2.2		 3bcrA-5obwA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 6 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.11A 3dd1A-5obwA:
undetectable		 3dd1A-5obwA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 6 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.08A 3dd1B-5obwA:
undetectable		 3dd1B-5obwA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 6 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.09A 3ddsA-5obwA:
undetectable		 3ddsA-5obwA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 6 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.07A 3ddsB-5obwA:
undetectable		 3ddsB-5obwA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 6 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.11A 3ddwA-5obwA:
undetectable		 3ddwA-5obwA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 6 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.09A 3ddwB-5obwA:
undetectable		 3ddwB-5obwA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.94A 3uboB-5obwA:
undetectable		 3uboB-5obwA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 LEU A 332
VAL A 333
SER A 335
VAL A 185
LEU A 187
 None
 1.28A 3vt3A-5obwA:
undetectable		 3vt3A-5obwA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 LEU A 332
VAL A 333
SER A 335
VAL A 185
LEU A 187
 None
 1.27A 3vt7A-5obwA:
undetectable		 3vt7A-5obwA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 1.00A 4e3aA-5obwA:
undetectable		 4e3aA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.97A 4jksA-5obwA:
undetectable		 4jksA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.96A 4jksB-5obwA:
undetectable		 4jksB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.96A 4jkuA-5obwA:
undetectable		 4jkuA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.97A 4jkuB-5obwA:
undetectable		 4jkuB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4k8cA-5obwA:
undetectable		 4k8cA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4k8cB-5obwA:
undetectable		 4k8cB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.97A 4k8kA-5obwA:
undetectable		 4k8kA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.96A 4k8kB-5obwA:
undetectable		 4k8kB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4k8pA-5obwA:
undetectable		 4k8pA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.99A 4k8pB-5obwA:
undetectable		 4k8pB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4k8tA-5obwA:
undetectable		 4k8tA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 1.00A 4k8tB-5obwA:
undetectable		 4k8tB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.97A 4k93A-5obwA:
undetectable		 4k93A-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.97A 4k93B-5obwA:
undetectable		 4k93B-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4k9cA-5obwA:
undetectable		 4k9cA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.97A 4k9cB-5obwA:
undetectable		 4k9cB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.99A 4k9iA-5obwA:
undetectable		 4k9iA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 1.00A 4k9iB-5obwA:
undetectable		 4k9iB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.97A 4kadA-5obwA:
undetectable		 4kadA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4kadB-5obwA:
undetectable		 4kadB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4kahA-5obwA:
undetectable		 4kahA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4kahB-5obwA:
undetectable		 4kahB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4kalA-5obwA:
undetectable		 4kalA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4kalB-5obwA:
undetectable		 4kalB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.97A 4kanA-5obwA:
undetectable		 4kanA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.97A 4kanB-5obwA:
undetectable		 4kanB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 1.00A 4kbeA-5obwA:
undetectable		 4kbeA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.99A 4kbeB-5obwA:
undetectable		 4kbeB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.97A 4lbgA-5obwA:
undetectable		 4lbgA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.97A 4lbgB-5obwA:
undetectable		 4lbgB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.99A 4lbxA-5obwA:
undetectable		 4lbxA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.99A 4lbxB-5obwA:
undetectable		 4lbxB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4lc4A-5obwA:
undetectable		 4lc4A-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4lc4B-5obwA:
undetectable		 4lc4B-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4lcaA-5obwA:
undetectable		 4lcaA-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 ASN A 204
GLY A 180
GLY A 181
SER A  70
ASP A 210
 GOL  A 410 ( 3.9A)
ADP  A 402 (-3.5A)
None
None
None
 0.98A 4lcaB-5obwA:
undetectable		 4lcaB-5obwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 LEU A  13
ASP A 349
VAL A 352
GLY A 179
PRO A 126
 None
None
None
ADP  A 402 (-3.3A)
PO4  A 403 ( 4.2A)
 1.01A 4njuA-5obwA:
undetectable		 4njuA-5obwA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		5 / 12 LEU A  13
ASP A 349
VAL A 352
GLY A 179
PRO A 126
 None
None
None
ADP  A 402 (-3.3A)
PO4  A 403 ( 4.2A)
 1.03A 4njuC-5obwA:
undetectable		 4njuC-5obwA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 7 GLU A 154
THR A  15
GLY A  14
THR A  16
 PO4  A 403 (-2.9A)
GOL  A 410 (-2.9A)
PO4  A 403 ( 3.2A)
ADP  A 402 (-3.8A)
 0.98A 4qwpB-5obwA:
undetectable		 4qwpB-5obwA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		6 / 10 GLY A 179
GLY A 208
LYS A 250
SER A 254
GLY A 322
SER A 323
 ADP  A 402 (-3.3A)
ADP  A 402 (-3.3A)
ADP  A 402 (-2.9A)
ADP  A 402 (-2.7A)
ADP  A 402 (-3.2A)
ADP  A 402 (-3.6A)
 1.06A 5aqfA-5obwA:
46.9		 5aqfA-5obwA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		6 / 10 GLY A 179
LYS A 250
SER A 254
GLY A 322
SER A 323
ARG A 325
 ADP  A 402 (-3.3A)
ADP  A 402 (-2.9A)
ADP  A 402 (-2.7A)
ADP  A 402 (-3.2A)
ADP  A 402 (-3.6A)
None
 1.12A 5aqfA-5obwA:
46.9		 5aqfA-5obwA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		7 / 10 GLY A 180
GLY A 208
GLU A 247
LYS A 250
SER A 254
GLY A 322
SER A 323
 ADP  A 402 (-3.5A)
ADP  A 402 (-3.3A)
ADP  A 402 (-3.6A)
ADP  A 402 (-2.9A)
ADP  A 402 (-2.7A)
ADP  A 402 (-3.2A)
ADP  A 402 (-3.6A)
 0.56A 5aqfA-5obwA:
46.9		 5aqfA-5obwA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		6 / 10 GLY A 179
GLY A 208
LYS A 250
SER A 254
GLY A 322
SER A 323
 ADP  A 402 (-3.3A)
ADP  A 402 (-3.3A)
ADP  A 402 (-2.9A)
ADP  A 402 (-2.7A)
ADP  A 402 (-3.2A)
ADP  A 402 (-3.6A)
 1.06A 5aqfC-5obwA:
46.7		 5aqfC-5obwA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		6 / 10 GLY A 179
LYS A 250
SER A 254
GLY A 322
SER A 323
ARG A 325
 ADP  A 402 (-3.3A)
ADP  A 402 (-2.9A)
ADP  A 402 (-2.7A)
ADP  A 402 (-3.2A)
ADP  A 402 (-3.6A)
None
 1.14A 5aqfC-5obwA:
46.7		 5aqfC-5obwA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		7 / 10 GLY A 180
GLY A 208
GLU A 247
LYS A 250
SER A 254
GLY A 322
SER A 323
 ADP  A 402 (-3.5A)
ADP  A 402 (-3.3A)
ADP  A 402 (-3.6A)
ADP  A 402 (-2.9A)
ADP  A 402 (-2.7A)
ADP  A 402 (-3.2A)
ADP  A 402 (-3.6A)
 0.55A 5aqfC-5obwA:
46.7		 5aqfC-5obwA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		7 / 10 GLY A 179
GLY A 208
LYS A 250
SER A 254
GLY A 322
SER A 323
ARG A 325
 ADP  A 402 (-3.3A)
ADP  A 402 (-3.3A)
ADP  A 402 (-2.9A)
ADP  A 402 (-2.7A)
ADP  A 402 (-3.2A)
ADP  A 402 (-3.6A)
None
 1.12A 5aqyA-5obwA:
18.0		 5aqyA-5obwA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		7 / 10 GLY A 180
GLY A 208
GLU A 247
LYS A 250
SER A 254
GLY A 322
SER A 323
 ADP  A 402 (-3.5A)
ADP  A 402 (-3.3A)
ADP  A 402 (-3.6A)
ADP  A 402 (-2.9A)
ADP  A 402 (-2.7A)
ADP  A 402 (-3.2A)
ADP  A 402 (-3.6A)
 0.57A 5aqyA-5obwA:
18.0		 5aqyA-5obwA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_ACTA305_0
(CARBONIC ANHYDRASE 4)		 5obw CHAPERONE PROTEIN
DNAK
(Mycoplasma
genitalium) 		4 / 4 GLN A 359
VAL A 122
GLU A 149
ILE A   8
 None
 1.46A 5jncA-5obwA:
undetectable		 5jncA-5obwA:
undetectable